trilostane [Supplementary Concept]

inhibits conversion of pregnenolone to progesterone; adrenal blocking agent used in treatment of Cushing's syndrome

Date introduced: January 1, 1975

MeSH Unique ID: C009954

Registry Number: L0FPV48Q5R

Heading Mapped to:

• Dihydrotestosterone/analogs and derivatives

Entry Terms:

• 4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile
• Modrenal
• WIN 24,540

Previous Indexing:

• ANDROSTANES (75-80)
• ANDROSTANOLS (80-82)
• NITRILES (75-82)

Pharmacologic Action:

• Abortifacient Agents, Steroidal
• Antineoplastic Agents
• Enzyme Inhibitors