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Osteoarthritis of hip(OS5)

MedGen UID:
14530
Concept ID:
C0029410
Disease or Syndrome
Synonyms: OS5; OSTEOARTHRITIS SUSCEPTIBILITY 5; Osteoarthritis, Hip
SNOMED CT: Degenerative joint disease of hip (239872002); OA - Osteoarthritis of hip (239872002); Osteoarthritis of hip (239872002)
 
Gene (location): GDF5 (20q11.22)
OMIM®: 612400

Definition

Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGOsteoarthritis of hip

Recent clinical studies

Etiology

Conaghan PG, O'Brien CM, Wilson M, Schofield JP
Osteoarthritis Cartilage 2011 Aug;19(8):930-8. Epub 2011 Apr 6 doi: 10.1016/j.joca.2011.03.011. [Epub ahead of print] PMID: 21477658
van Ittersum MW, Bieleman HJ, Reneman MF, Oosterveld FG, Groothoff JW, van der Schans CP
J Occup Rehabil 2009 Sep;19(3):238-44. Epub 2009 May 15 doi: 10.1007/s10926-009-9179-y. [Epub ahead of print] PMID: 19444597
Heuts PH, de Bie R, Drietelaar M, Aretz K, Hopman-Rock M, Bastiaenen CH, Metsemakers JF, van Weel C, van Schayck O
J Rheumatol 2005 Mar;32(3):543-9. PMID: 15742451
van Baar ME, Dekker J, Oostendorp RA, Bijl D, Voorn TB, Bijlsma JW
Ann Rheum Dis 2001 Dec;60(12):1123-30. PMID: 11709454Free PMC Article
Björkenheim JM, Helland J, Peltonen J
J Int Med Res 1985;13(5):263-9. PMID: 3902531

Diagnosis

Lechner M, Steirer I, Brinkhaus B, Chen Y, Krist-Dungl C, Koschier A, Gantschacher M, Neumann K, Zauner-Dungl A
J Altern Complement Med 2011 Jun;17(6):539-47. doi: 10.1089/acm.2010.0602. PMID: 21649520
Kinds MB, Welsing PM, Vignon EP, Bijlsma JW, Viergever MA, Marijnissen AC, Lafeber FP
Osteoarthritis Cartilage 2011 Jul;19(7):768-78. Epub 2011 Jan 31 doi: 10.1016/j.joca.2011.01.015. [Epub ahead of print] PMID: 21281726
van Ittersum MW, Bieleman HJ, Reneman MF, Oosterveld FG, Groothoff JW, van der Schans CP
J Occup Rehabil 2009 Sep;19(3):238-44. Epub 2009 May 15 doi: 10.1007/s10926-009-9179-y. [Epub ahead of print] PMID: 19444597
Bijl D, Dekker J, van Baar ME, Oostendorp RA, Lemmens AM, Bijlsma JW, Voorn TB
Scand J Rheumatol 1998;27(5):347-51. PMID: 9808397
Murtagh J
Aust Fam Physician 1990 Mar;19(3):389. PMID: 2334341

Therapy

Conaghan PG, O'Brien CM, Wilson M, Schofield JP
Osteoarthritis Cartilage 2011 Aug;19(8):930-8. Epub 2011 Apr 6 doi: 10.1016/j.joca.2011.03.011. [Epub ahead of print] PMID: 21477658
Wandel S, Jüni P, Tendal B, Nüesch E, Villiger PM, Welton NJ, Reichenbach S, Trelle S
BMJ 2010 Sep 16;341:c4675. PMID: 20847017Free PMC Article
Heuts PH, de Bie R, Drietelaar M, Aretz K, Hopman-Rock M, Bastiaenen CH, Metsemakers JF, van Weel C, van Schayck O
J Rheumatol 2005 Mar;32(3):543-9. PMID: 15742451
van Baar ME, Dekker J, Oostendorp RA, Bijl D, Voorn TB, Bijlsma JW
Ann Rheum Dis 2001 Dec;60(12):1123-30. PMID: 11709454Free PMC Article
Björkenheim JM, Helland J, Peltonen J
J Int Med Res 1985;13(5):263-9. PMID: 3902531

Prognosis

Jansen MJ, Hendriks EJ, Oostendorp RA, Dekker J, De Bie RA
Eur J Phys Rehabil Med 2010 Sep;46(3):337-45. Epub 2010 May 6 [Epub ahead of print] PMID: 20926999
Schencking M, Otto A, Deutsch T, Sandholzer H
BMC Musculoskelet Disord 2009 Aug 19;10:104. doi: 10.1186/1471-2474-10-104. [Epub ahead of print] PMID: 19689824Free PMC Article
Marumo K, Sato Y, Suzuki H, Kurosaka D
J Orthop Sci 2006 Mar;11(2):154-8. doi: 10.1007/s00776-005-0989-2. PMID: 16568387
van Baar ME, Dekker J, Oostendorp RA, Bijl D, Voorn TB, Bijlsma JW
Ann Rheum Dis 2001 Dec;60(12):1123-30. PMID: 11709454Free PMC Article

Clinical prediction guides

Conaghan PG, O'Brien CM, Wilson M, Schofield JP
Osteoarthritis Cartilage 2011 Aug;19(8):930-8. Epub 2011 Apr 6 doi: 10.1016/j.joca.2011.03.011. [Epub ahead of print] PMID: 21477658
van Ittersum MW, Bieleman HJ, Reneman MF, Oosterveld FG, Groothoff JW, van der Schans CP
J Occup Rehabil 2009 Sep;19(3):238-44. Epub 2009 May 15 doi: 10.1007/s10926-009-9179-y. [Epub ahead of print] PMID: 19444597
Rossignol M, Leclerc A, Allaert FA, Rozenberg S, Valat JP, Avouac B, Coste P, Litvak E, Hilliquin P
Occup Environ Med 2005 Nov;62(11):772-7. doi: 10.1136/oem.2005.020057. PMID: 16234403Free PMC Article
Heuts PH, de Bie R, Drietelaar M, Aretz K, Hopman-Rock M, Bastiaenen CH, Metsemakers JF, van Weel C, van Schayck O
J Rheumatol 2005 Mar;32(3):543-9. PMID: 15742451
van Baar ME, Dekker J, Oostendorp RA, Bijl D, Voorn TB, Bijlsma JW
Ann Rheum Dis 2001 Dec;60(12):1123-30. PMID: 11709454Free PMC Article

Recent systematic reviews

Kinds MB, Welsing PM, Vignon EP, Bijlsma JW, Viergever MA, Marijnissen AC, Lafeber FP
Osteoarthritis Cartilage 2011 Jul;19(7):768-78. Epub 2011 Jan 31 doi: 10.1016/j.joca.2011.01.015. [Epub ahead of print] PMID: 21281726
Wandel S, Jüni P, Tendal B, Nüesch E, Villiger PM, Welton NJ, Reichenbach S, Trelle S
BMJ 2010 Sep 16;341:c4675. PMID: 20847017Free PMC Article

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