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Increased bone mineral density

MedGen UID:
451275
Concept ID:
CN116733
Finding
Synonyms: Increased bone density; Osteosclerosis; Osteosclerosis of bones
 

Definition

An abnormal increase of bone mineral density, that is, of the amount of matter per cubic centimeter of bones which is often refered to as osteosclerosis. Osteosclerosis can be detected on radiological examination as an increased whiteness (density) of affected bones. [from HPO]

Recent clinical studies

Etiology

Hagino H, Yoshida S, Hashimoto J, Matsunaga M, Tobinai M, Nakamura T
Calcif Tissue Int 2014 Dec;95(6):557-63. Epub 2014 Nov 7 doi: 10.1007/s00223-014-9927-7. [Epub ahead of print] PMID: 25377907Free PMC Article
Heise V, Galli-Lysak I, Villiger PM, Aeberli D
J Musculoskelet Neuronal Interact 2014 Jun;14(2):189-94. PMID: 24879022
Gogakos A, Logan JG, Waung JA, Bassett JH, Glüer CC, Reid DM, Felsenberg D, Roux C, Eastell R, Williams GR
Eur J Endocrinol 2014 Apr;170(4):637-44. Epub 2014 Mar 13 doi: 10.1530/EJE-13-1009. PMID: 24480136
Sohn S, Yoon JW, Chung CK
J Clin Densitom 2014 Jan-Mar;17(1):195-9. Epub 2013 May 30 doi: 10.1016/j.jocd.2013.04.005. [Epub ahead of print] PMID: 23726874
Sohn S, Chung CK
Calcif Tissue Int 2013 Jan;92(1):28-34. Epub 2012 Oct 27 doi: 10.1007/s00223-012-9662-x. [Epub ahead of print] PMID: 23104450

Diagnosis

Sohn S, Yoon JW, Chung CK
J Clin Densitom 2014 Jan-Mar;17(1):195-9. Epub 2013 May 30 doi: 10.1016/j.jocd.2013.04.005. [Epub ahead of print] PMID: 23726874
Lowitz T, Museyko O, Bousson V, Laouisset L, Kalender WA, Laredo JD, Engelke K
Osteoarthritis Cartilage 2013 Jul;21(7):957-64. Epub 2013 Apr 18 doi: 10.1016/j.joca.2013.04.006. [Epub ahead of print] PMID: 23602981
Wada K, Harada D, Michigami T, Tachikawa K, Nakano Y, Kashiwagi H, Yamashita S, Sano T, Seino Y
J Pediatr Endocrinol Metab 2013;26(5-6):575-7. doi: 10.1515/jpem-2013-0007. PMID: 23412864
Sohn S, Chung CK
Calcif Tissue Int 2013 Jan;92(1):28-34. Epub 2012 Oct 27 doi: 10.1007/s00223-012-9662-x. [Epub ahead of print] PMID: 23104450
Rivera M, Humeres P, González P
Clin Nucl Med 1999 Jan;24(1):51-3. PMID: 9890494

Therapy

Hagino H, Yoshida S, Hashimoto J, Matsunaga M, Tobinai M, Nakamura T
Calcif Tissue Int 2014 Dec;95(6):557-63. Epub 2014 Nov 7 doi: 10.1007/s00223-014-9927-7. [Epub ahead of print] PMID: 25377907Free PMC Article
Di Martino A, Franceschi F, Papalia R, Marini M, Prossomariti G, Maffulli N, Denaro V
Surgeon 2012 Feb;10(1):20-4. Epub 2011 Feb 9 doi: 10.1016/j.surge.2011.01.001. [Epub ahead of print] PMID: 22233553
Bradbury LA, Barlow S, Geoghegan F, Hannon RA, Stuckey SL, Wass JA, Russell RG, Brown MA, Duncan EL
Osteoporos Int 2012 Jan;23(1):285-94. Epub 2011 Jul 8 doi: 10.1007/s00198-011-1658-2. [Epub ahead of print] PMID: 21739105
Pullerits R, d'Elia HF, Tarkowski A, Carlsten H
Rheumatology (Oxford) 2009 Jul;48(7):785-90. Epub 2009 May 4 doi: 10.1093/rheumatology/kep079. [Epub ahead of print] PMID: 19416946
Rejnmark L, Vestergaard P, Hermann AP, Brot C, Eiken P, Mosekilde L
Calcif Tissue Int 2008 Jan;82(1):1-11. Epub 2008 Jan 4 doi: 10.1007/s00223-007-9087-0. [Epub ahead of print] PMID: 18175033

Prognosis

Hagino H, Yoshida S, Hashimoto J, Matsunaga M, Tobinai M, Nakamura T
Calcif Tissue Int 2014 Dec;95(6):557-63. Epub 2014 Nov 7 doi: 10.1007/s00223-014-9927-7. [Epub ahead of print] PMID: 25377907Free PMC Article
Di Martino A, Franceschi F, Papalia R, Marini M, Prossomariti G, Maffulli N, Denaro V
Surgeon 2012 Feb;10(1):20-4. Epub 2011 Feb 9 doi: 10.1016/j.surge.2011.01.001. [Epub ahead of print] PMID: 22233553
Bradbury LA, Barlow S, Geoghegan F, Hannon RA, Stuckey SL, Wass JA, Russell RG, Brown MA, Duncan EL
Osteoporos Int 2012 Jan;23(1):285-94. Epub 2011 Jul 8 doi: 10.1007/s00198-011-1658-2. [Epub ahead of print] PMID: 21739105
Rejnmark L, Vestergaard P, Hermann AP, Brot C, Eiken P, Mosekilde L
Calcif Tissue Int 2008 Jan;82(1):1-11. Epub 2008 Jan 4 doi: 10.1007/s00223-007-9087-0. [Epub ahead of print] PMID: 18175033
Sigurdsson G, Franzson L
J Intern Med 2001 Jul;250(1):51-6. PMID: 11454142

Clinical prediction guides

Hagino H, Yoshida S, Hashimoto J, Matsunaga M, Tobinai M, Nakamura T
Calcif Tissue Int 2014 Dec;95(6):557-63. Epub 2014 Nov 7 doi: 10.1007/s00223-014-9927-7. [Epub ahead of print] PMID: 25377907Free PMC Article
Heise V, Galli-Lysak I, Villiger PM, Aeberli D
J Musculoskelet Neuronal Interact 2014 Jun;14(2):189-94. PMID: 24879022
Sohn S, Yoon JW, Chung CK
J Clin Densitom 2014 Jan-Mar;17(1):195-9. Epub 2013 May 30 doi: 10.1016/j.jocd.2013.04.005. [Epub ahead of print] PMID: 23726874
Lowitz T, Museyko O, Bousson V, Laouisset L, Kalender WA, Laredo JD, Engelke K
Osteoarthritis Cartilage 2013 Jul;21(7):957-64. Epub 2013 Apr 18 doi: 10.1016/j.joca.2013.04.006. [Epub ahead of print] PMID: 23602981
Sohn S, Chung CK
Calcif Tissue Int 2013 Jan;92(1):28-34. Epub 2012 Oct 27 doi: 10.1007/s00223-012-9662-x. [Epub ahead of print] PMID: 23104450

Recent systematic reviews

Pinzone MR, Moreno S, Cacopardo B, Nunnari G
AIDS Rev 2014 Oct-Dec;16(4):213-22. PMID: 25300622
Gorter EA, Hamdy NA, Appelman-Dijkstra NM, Schipper IB
Bone 2014 Jul;64:288-97. Epub 2014 May 2 doi: 10.1016/j.bone.2014.04.026. [Epub ahead of print] PMID: 24792958
Konstantinidis I, Papageorgiou SN, Kyrgidis A, Tzellos TG, Kouvelas D
Rev Recent Clin Trials 2013 Mar;8(1):48-60. PMID: 23016823
Bradbury LA, Barlow S, Geoghegan F, Hannon RA, Stuckey SL, Wass JA, Russell RG, Brown MA, Duncan EL
Osteoporos Int 2012 Jan;23(1):285-94. Epub 2011 Jul 8 doi: 10.1007/s00198-011-1658-2. [Epub ahead of print] PMID: 21739105
Jugdaohsingh R, O'Connell MA, Sripanyakorn S, Powell JJ
Proc Nutr Soc 2006 Aug;65(3):291-310. PMID: 16923313

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