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Hereditary palmoplantar keratoderma

MedGen UID:
44017
Concept ID:
C0022596
Disease or Syndrome
Synonyms: Keratoderma; Palmoplantar keratoderma
 

Definition

Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis). [from MeSH]

Recent clinical studies

Etiology

Goldberg I, Sprecher E, Schwartz ME, Gaitini D
Dermatology 2013;226(4):365-70. Epub 2013 Jul 9 doi: 10.1159/000351321. [Epub ahead of print] PMID: 24030314
Ogunbiyi SO, Deguara J, Moss C, Burnand KG
Lymphology 2009 Jun;42(2):85-7. PMID: 19725273
Nielsen PG
Acta Derm Venereol Suppl (Stockh) 1994;188:1-60. PMID: 9868488
Hamm H, Happle R, Butterfass T, Traupe H
Dermatologica 1988;177(3):138-45. PMID: 2971584
Nielsen PG
Dermatologica 1985;171(5):305-7. PMID: 2416605

Diagnosis

Goldberg I, Sprecher E, Schwartz ME, Gaitini D
Dermatology 2013;226(4):365-70. Epub 2013 Jul 9 doi: 10.1159/000351321. [Epub ahead of print] PMID: 24030314
Ebtisam E
Dermatol Nurs 2009 Nov-Dec;21(6):351-3. PMID: 20102020
Adams SP
Can Fam Physician 1997 Jul;43:1219, 1225. PMID: 9241457Free PMC Article
Hamm H, Happle R, Butterfass T, Traupe H
Dermatologica 1988;177(3):138-45. PMID: 2971584
Gamborg Nielsen P
Dermatologica 1984;168(6):293-5. PMID: 6235137

Therapy

Sehgal VN, Sardana K, Sharma S, Raut D
Skinmed 2004 Nov-Dec;3(6):323-30; quiz 331-2. PMID: 15538081
Sehgal VN, Kumar S, Narayan S
Int J Dermatol 2001 Feb;40(2):130-2. PMID: 11328395
Kragballe K, Steijlen PM, Ibsen HH, van de Kerkhof PC, Esmann J, Sorensen LH, Axelsen MB
Arch Dermatol 1995 May;131(5):556-60. PMID: 7741542
Fritsch P, Hönigsmann H, Jaschke E
Br J Dermatol 1978 Nov;99(5):561-8. PMID: 152116

Prognosis

Ogunbiyi SO, Deguara J, Moss C, Burnand KG
Lymphology 2009 Jun;42(2):85-7. PMID: 19725273
Nakajima K, Nakano H, Takiyoshi N, Rokunohe A, Ikenaga S, Aizu T, Kaneko T, Mitsuhashi Y, Sawamura D
Dermatology 2008;217(1):58-62. Epub 2008 Apr 9 doi: 10.1159/000124340. [Epub ahead of print] PMID: 18401176
Sehgal VN, Sardana K, Sharma S, Raut D
Skinmed 2004 Nov-Dec;3(6):323-30; quiz 331-2. PMID: 15538081
Wong ML, Tay JS
J Singapore Paediatr Soc 1991;33(1-2):45-8. PMID: 1784110

Clinical prediction guides

Miljković J, Kansky A
Acta Dermatovenerol Alp Pannonica Adriat 2009 Sep;18(3):114-6. PMID: 19784524
Mozzillo N, Nunziata CA, Caracò C, Fazioli F, Botti G; Melanoma Cooperative Group
J Surg Oncol 2003 Dec;84(4):229-33. doi: 10.1002/jso.10317. PMID: 14756434
Stanimirović A, Kansky A, Basta-Juzbasić A, Skerlev M, Beck T
J Am Acad Dermatol 1993 Sep;29(3):435-7. PMID: 8349860
Gamborg Nielsen P
Clin Genet 1985 Nov;28(5):361-6. PMID: 2935332
Tezuka T
Dermatologica 1984;169(3):138-45. PMID: 6207058

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