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Schizophrenia 3(SCZD3)

MedGen UID:
324936
Concept ID:
C1838069
Disease or Syndrome
Synonyms: SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 6-RELATED; SCZD3
 
OMIM®: 600511

Clinical features

Schizophrenia
MedGen UID:
48574
Concept ID:
C0036341
Mental or Behavioral Dysfunction
Schizophrenia is a psychosis, a disorder of thought and sense of self. Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. There is no characteristic pathology, such as neurofibrillary tangles in Alzheimer disease (104300). Schizophrenia is a common disorder with a lifetime prevalence of approximately 1%. It is highly heritable but the genetics are complex. This may not be a single entity. Reviews In a review of schizophrenia, van Os and Kapur (2009) noted that in Japan the term schizophrenia was abandoned and the illness is now called integration-dysregulation syndrome.

Recent clinical studies

Etiology

Julie G, Hamdan FF, Rouleau GA
J Vis Exp 2011 Jun 15;(52) doi: 10.3791/2534. PMID: 21712793Free PMC Article

Prognosis

Julie G, Hamdan FF, Rouleau GA
J Vis Exp 2011 Jun 15;(52) doi: 10.3791/2534. PMID: 21712793Free PMC Article

Clinical prediction guides

Julie G, Hamdan FF, Rouleau GA
J Vis Exp 2011 Jun 15;(52) doi: 10.3791/2534. PMID: 21712793Free PMC Article
Austin J, Hoogendoorn B, Buckland P, Speight G, Cardno A, Bowen T, Williams N, Spurlock G, Sanders R, Jones L, Murphy K, McCarthy G, McGuffin P, Owen MJ, O'Donovan MC
Mol Psychiatry 2000 Mar;5(2):208-12. PMID: 10822351

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