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Results: 1 to 20 of 63

1.

Cellular Blue Nevus

A blue nevus characterized by a multinodular cellular infiltrate with a dumb-bell architecture occupying the reticular dermis. The cellular infiltrate often extends into the subcutaneous tissue. The cellular infiltrate is composed of spindle-shaped melanocytes with pale cytoplasm alternating with bundles of pigmented spindle-shaped melanocytes. In occasional cases an increased mitotic activity, focal necrosis, and nuclear pleomorphism may be seen. Such cases with atypical features may have an uncertain malignant potential. [from NCI]

MedGen UID:
137764
Concept ID:
C0334448
Neoplastic Process
2.

Nevus

Moles are growths on the skin. They happen when cells in the skin, called melanocytes, grow in a cluster with tissue surrounding them. Moles are very common. Most people have between 10 and 40 moles. A person may develop new moles from time to time, usually until about age 40. Moles are usually pink, tan or brown. They can be flat or raised. They are usually round or oval and no larger than a pencil eraser. About one out of every ten people has at least one unusual (or atypical) mole that looks different from an ordinary mole. The medical term for these unusual moles is dysplastic nevi. They may be more likely than ordinary moles to develop into melanoma, a type of skin cancer. Because of this, you should have a healthcare professional check your moles if they look unusual, grow larger, change in color or outline, or in any other way. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
45074
Concept ID:
C0027960
Neoplastic Process
3.

Blue nevus

MedGen UID:
452034
Concept ID:
CN117704
Finding
4.

Nevus

A nevus is a type of hamartoma that is a circumscribed stable malformation of the skin. [from HPO]

MedGen UID:
425158
Concept ID:
CN003400
Finding
5.

atypia morphology

The condition of being irregular or not conforming to type. [from NCI]

MedGen UID:
152855
Concept ID:
C0741302
Finding
6.

Nevus, Blue

Usually a benign tumor, that commonly presents as a solitary blue nodule with spindled MELANOCYTES covered by smooth SKIN. Several variants have been identified, one variant being malignant. The blue color is caused by large, densely packed melanocytes deep in the DERMIS of the nevus. In CHILDREN, they usually occur on the BUTTOCKS and LUMBOSACRAL REGION and are referred to as cellular blue nevi. Malignant blue nevi are more commonly found on the SCALP. [from MeSH]

MedGen UID:
104930
Concept ID:
C0206736
Neoplastic Process
7.

Recurrence (disease attribute)

The return of a sign, symptom, or disease after a remission. [from MeSH]

MedGen UID:
416712
Concept ID:
C2825055
Pathologic Function
8.

Necrosis

A permanent cessation of all vital functions of a tissue. [GOC:dph] [from GO]

MedGen UID:
10199
Concept ID:
C0027540
Pathologic Function
9.

Malignant melanoma

A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [from MeSH]

MedGen UID:
9944
Concept ID:
C0025202
Neoplastic Process
10.

Aneuploidy

The chromosomal constitution of cells which deviate from the normal by the addition or subtraction of CHROMOSOMES, chromosome pairs, or chromosome fragments. In a normally diploid cell (DIPLOIDY) the loss of a chromosome pair is termed nullisomy (symbol: 2N-2), the loss of a single chromosome is MONOSOMY (symbol: 2N-1), the addition of a chromosome pair is tetrasomy (symbol: 2N+2), the addition of a single chromosome is TRISOMY (symbol: 2N+1). [from MeSH]

MedGen UID:
294
Concept ID:
C0002938
Cell or Molecular Dysfunction
11.

Alive

MedGen UID:
749206
Concept ID:
C2584946
Finding
12.

Dead

MedGen UID:
736056
Concept ID:
C1546956
Finding
13.

Melanoma

The presence of a `melanoma` (MPATH:359), a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea). [from HPO]

MedGen UID:
505377
Concept ID:
CN002586
Finding
14.

History of previous events

The aggregate of past events; the continuum of events occurring in succession leading from the past to the present; a record or narrative description of past events. [from NCI]

MedGen UID:
389153
Concept ID:
C2004062
Finding
15.

Staining (finding)

MedGen UID:
352872
Concept ID:
C1704680
Finding
16.

Nuclear Pleomorphism

Having nuclei with various distinct forms. [from NCI]

MedGen UID:
273607
Concept ID:
C1518437
Finding
17.

Hyperchromatism

A morphologic finding referring to the presence of darkly stained nuclei due to abundance of DNA on hematoxylin-eosin stained sections. It is suggestive of malignancy. [from NCI]

MedGen UID:
137708
Concept ID:
C0333910
Cell or Molecular Dysfunction
18.

Cytologic atypia

MedGen UID:
90720
Concept ID:
C0333865
Cell or Molecular Dysfunction
19.

History of

A record of a patient's background regarding health and the occurrence of disease events of the individual. In addition, personal medical history may be a variable in epidemiologic studies. [from NCI]

MedGen UID:
82657
Concept ID:
C0262926
Finding
20.

Neoplasm Metastasis

The spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a "metastatic tumor" or a "metastasis." The metastatic tumor contains cells that are like those in the original (primary) tumor. [from NCI]

MedGen UID:
45032
Concept ID:
C0027627
Neoplastic Process

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