Display Settings:

Format
Items per page

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 1 to 20 of 26

1.

Dopamine

A monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1 adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output. [from NCI]

MedGen UID:
41644
Concept ID:
C0013030
Pharmacologic Substance
2.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system. . It is important to get plenty of calcium in the foods you eat. Foods rich in calcium include dairy products such as milk, cheese and yogurt, and leafy, green vegetables. The exact amount of calcium you need depends on your age and other factors. Growing children and teenagers need more calcium than young adults. Older women need plenty of calcium to prevent osteoporosis. People who do not eat enough high-calcium foods should take a calcium supplement. NIH: National Institutes of Health Office of Dietary Supplements.  [from MedlinePlus]

MedGen UID:
710
Concept ID:
C0006675
Pharmacologic Substance
3.

Amphetamine

a powerful central nerve system stimulant [from CHV]

MedGen UID:
266
Concept ID:
C0002658
Pharmacologic Substance
4.

MK-801

MedGen UID:
167242
Concept ID:
C0813872
Pharmacologic Substance
5.

Phosphorylation

A process in which a phosphate group is added to a molecule, such as a sugar or a protein. [from NCI]

MedGen UID:
10742
Concept ID:
C0031715
Molecular Function
6.

Forskolin

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive ionotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland. [from MeSH]

MedGen UID:
8901
Concept ID:
C0016601
Pharmacologic Substance
7.

Cocaine

Cocaine is a powerful drug that stimulates the brain. People who use it can form a strong addiction. They may have to use more and more of the drug to get high. It's sold on the street as a fine, white powder. There are two forms of cocaine: hydrochloride salt and freebase. The salt dissolves in water. People can take it in a vein or in the nose. The freebase form can be smoked. Crack is the street name of a smokable form of cocaine. . No matter how cocaine is taken, it is dangerous. Some of the most common serious problems include : - Heart problems, including heart attacks . - Respiratory effects, including respiratory failure . - Nervous system problems, including strokes . - Digestive problems . Any of these can be fatal. Using cocaine with alcohol is a common cause of drug-related death. . NIH: National Institute on Drug Abuse.  [from MedlinePlus]

MedGen UID:
3135
Concept ID:
C0009170
Pharmacologic Substance
8.

Cyclic adenosine monophosphate

An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. (MeSH) [from NCI]

MedGen UID:
1328
Concept ID:
C0001455
Pharmacologic Substance
9.

NMDA receptor antagonist

MedGen UID:
671129
Concept ID:
C0598695
Pharmacologic Substance
10.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
11.

Chronic

A disease or condition that persists or progresses over a long period of time. [from NCI]

MedGen UID:
104657
Concept ID:
C0205191
12.

Centramina

MedGen UID:
257401
Concept ID:
C1448393
Pharmacologic Substance
13.

Thyramine

MedGen UID:
149069
Concept ID:
C0729148
Pharmacologic Substance
14.

Mydrial

MedGen UID:
147560
Concept ID:
C0729147
Pharmacologic Substance
15.

Fenamine

MedGen UID:
147559
Concept ID:
C0729146
Pharmacologic Substance
16.

Intropin

MedGen UID:
147406
Concept ID:
C0721081
Pharmacologic Substance
17.

Dizocilpine Maleate

A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects. [from MeSH]

MedGen UID:
37173
Concept ID:
C0079246
Pharmacologic Substance
18.

Dizocilpine

10,11-dihydro-5-methyldibenzocyclohepten -5,10-imine; PCP analog, anticonvulsant, and excitatory aminoacid antagonist that acts on the calcium channel site of NMDA receptors; USP lists as a neuroprotectant. [from CRISP]

MedGen UID:
37172
Concept ID:
C0079245
Pharmacologic Substance
19.

Phenethylamine

MedGen UID:
20111
Concept ID:
C0070559
Pharmacologic Substance
20.

Phenethylamines

A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed) [from MeSH]

MedGen UID:
10698
Concept ID:
C0031399
Pharmacologic Substance

Display Settings:

Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...