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Results: 1 to 20 of 28

1.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Pharmacologic Substance
2.

Unable

MedGen UID:
721425
Concept ID:
C1299582
Finding
3.

Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570) [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
4.

Failing to produce an effect from some foregoing stimulus or agent. [from NCI]

MedGen UID:
116026
Concept ID:
C0237284
5.

Viral infections of the central nervous system

Viral infections of the brain, spinal cord, meninges, or perimeningeal spaces. [from MeSH]

MedGen UID:
91141
Concept ID:
C0348165
Disease or Syndrome
6.

Mononegavirales Infections

Infections with viruses of the order MONONEGAVIRALES. The concept includes FILOVIRIDAE INFECTIONS; PARAMYXOVIRIDAE INFECTIONS; and RHABDOVIRIDAE INFECTIONS. [from MeSH]

MedGen UID:
67005
Concept ID:
C0242916
Disease or Syndrome
7.

Disease due to Alphavirus

Virus diseases caused by members of the ALPHAVIRUS genus of the family TOGAVIRIDAE. [from MeSH]

MedGen UID:
64650
Concept ID:
C0206752
Disease or Syndrome
8.

Infections, Arenavirus

MedGen UID:
64426
Concept ID:
C0205671
Disease or Syndrome
9.

Disease due to Rhabdoviridae

Virus diseases caused by RHABDOVIRIDAE. Important infections include RABIES; EPHEMERAL FEVER; and vesicular stomatitis. [from MeSH]

MedGen UID:
60221
Concept ID:
C0206751
Disease or Syndrome
10.

Viral disease

disease produced by viruses. [from CRISP]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
11.

Viral meningitis

Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3) [from MeSH]

MedGen UID:
44355
Concept ID:
C0025297
Disease or Syndrome
12.

Lymphocytic Choriomeningitis

A form of meningitis caused by LYMPHOCYTIC CHORIOMENINGITIS VIRUS. MICE and other rodents serve as the natural hosts, and infection in humans usually occurs through inhalation or ingestion of infectious particles. Clinical manifestations include an influenza-like syndrome followed by stiff neck, alterations of mentation, ATAXIA, and incontinence. Maternal infections may result in fetal malformations and injury, including neonatal HYDROCEPHALUS, aqueductal stenosis, CHORIORETINITIS, and MICROCEPHALY. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3) [from MeSH]

MedGen UID:
44220
Concept ID:
C0024266
Disease or Syndrome
13.

Immunoglobulins

there are two types of polypeptide chains responsible for the biological and immunological properties of the different immunoglobulins, the heavy chain and the light chain; they are linked by covalent and non-covalent forces to give a four-chain Y-shaped structure based on pairs of identical heavy and light chains; each chain consists of a variable region and a constant region which are coded for by different genes; some immunoglobulin classes occur as polymers of this basic monomer. [from CRISP]

MedGen UID:
43841
Concept ID:
C0021027
Pharmacologic Substance
14.

Disease due to Togaviridae

Virus diseases caused by the TOGAVIRIDAE. [from MeSH]

MedGen UID:
21575
Concept ID:
C0040361
Disease or Syndrome
15.

Pachymeningitis

MedGen UID:
14570
Concept ID:
C0030167
Disease or Syndrome
16.

RNA Virus Infections

MedGen UID:
11250
Concept ID:
C0035690
Disease or Syndrome
17.

Interferon Type I

Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA). [from MeSH]

MedGen UID:
9509
Concept ID:
C0021743
Pharmacologic Substance
18.

Immune status

Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances. [from MeSH]

MedGen UID:
9426
Concept ID:
C0020964
Finding
19.

Immunity, Innate

The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS. [from MeSH]

MedGen UID:
7024
Concept ID:
C0020969
Pathologic Function
20.

Meningitis

Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6) [from MeSH]

MedGen UID:
6298
Concept ID:
C0025289
Disease or Syndrome

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