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Results: 4

1.

orlistat

A reversible active-site inhibitor of gastrointestinal lipases. Orlistat forms a covalent bond with the active serine site in gastric and pancreatic lipases, thereby inhibiting their activity and preventing dietary fat from being hydrolyzed and absorbed. (NCI04) [from NCI]

MedGen UID:
23289
Concept ID:
C0076275
Pharmacologic Substance
2.

Lipase

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3. [from MeSH]

MedGen UID:
9778
Concept ID:
C0023764
Pharmacologic Substance
3.

lipase inhibitor

MedGen UID:
692699
Concept ID:
C1268854
Pharmacologic Substance
4.

Gastrointestinal Lipase Inhibitor

An agent that inhibits lipases expressed by gastric and pancreatic epithelial cells. Typically, a gastrointestinal lipase inhibitor binds to lipases, blocks their activities and results in a diminished digestion and absorption of dietary fat. (NCI04) [from NCI]

MedGen UID:
275952
Concept ID:
C1517459
Pharmacologic Substance

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