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Results: 8

1.

Warfarin

A synthetic anticoagulant. Warfarin appears to inhibit the regeneration of vitamin K1 epoxide and so the synthesis of vitamin K dependent clotting factors, which include Factors II, VII, IX and X, and the anticoagulant proteins C and S. This inhibition results in a sequential depression of Factors VII, IX, X and II activities. Vitamin K is an essential cofactor for the post ribosomal synthesis of the vitamin K dependent clotting factors. The vitamin promotes the biosynthesis of gamma-carboxyglutamic acid residues in these proteins which are essential for biological activity. [from NCI]

MedGen UID:
22695
Concept ID:
C0043031
Pharmacologic Substance
2.

Diflunisal

A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN. [from MeSH]

MedGen UID:
8396
Concept ID:
C0012228
Pharmacologic Substance
3.

Apo-Diflunisal

MedGen UID:
293908
Concept ID:
C1569312
Pharmacologic Substance
4.

Nu-Diflunisal

MedGen UID:
292206
Concept ID:
C1569311
Pharmacologic Substance
5.

Novo-Diflunisal

MedGen UID:
292205
Concept ID:
C1569310
Pharmacologic Substance
6.

MedGen UID:
147216
Concept ID:
C0701140
7.

MedGen UID:
146967
Concept ID:
C0699201
8.

Protein binding capacity

MedGen UID:
700018
Concept ID:
C1276857
Molecular Function

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