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Results: 5

1.

Hydroxyzine hydrochloride

The hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05) [from NCI]

MedGen UID:
109004
Concept ID:
C0600110
Pharmacologic Substance
2.

Droperidol

A butyrophenone with anti-emetic, sedative and anti-anxiety properties. Although the exact mechanism through which droperidol exerts its effects is unknown, droperidol may block dopamine receptors in the chemoreceptor trigger zone (CTZ), which may lead to its anti-emetic effect. This agent may also bind to postsynaptic gamma-aminobutyric acid (GABA) receptors in the central nervous system (CNS), which increases the inhibitory effect of GABA and leads to sedative and anti-anxiety activities. [from NCI]

MedGen UID:
41657
Concept ID:
C0013136
Pharmacologic Substance
3.

Hydroxyzine

A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative. [from MeSH]

MedGen UID:
9353
Concept ID:
C0020404
Pharmacologic Substance
4.

Diazepam

antianxiety drug [from CHV]

MedGen UID:
3803
Concept ID:
C0012010
Pharmacologic Substance
5.

Diazepam

MedGen UID:
449998
Concept ID:
CN077523
Pharmacologic Substance

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