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Results: 4

1.

sorafenib

A synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. [from NCI]

MedGen UID:
273831
Concept ID:
C1516119
Pharmacologic Substance
2.

Cholangiocarcinoma

A rare type of cancer that develops in cells that line the bile ducts in the liver. Cancer that forms where the right and left ducts meet is called Klatskin tumor. [from NCI]

MedGen UID:
60210
Concept ID:
C0206698
Neoplastic Process
3.

Cholangiocarcinoma

Cholangiocarcinoma (CCA) is a biliary tract cancer (BTC, see this term) originating in the epithelium of the biliary tree, either intra or extra hepatic. [from ORDO]

MedGen UID:
798721
Concept ID:
CN205583
Neoplastic Process
4.

Visual Suppression

MedGen UID:
526147
Concept ID:
C0221103
Pathologic Function

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