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Takotsubo cardiomyopathy
Transient left ventricular apical ballooning syndrome or takotsubo cardiomyopathy is characterized by transient regional systolic dysfunction involving the left ventricular apex and/or mid-ventricle in the absence of obstructive coronary disease on coronary angiography. Patients present with an abrupt onset of angina-like chest pain, and have diffuse T-wave inversion, sometimes preceded by ST-segment elevation, and mild cardiac enzyme elevation. [from HPO]
Progressive multifocal leukoencephalopathy
A progressive demyelination within the central nervous system associated with reactivation of a latent JC virus infection. [from NCI]
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