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Results: 3

1.

Insulin resistance

Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. [from MeSH]

MedGen UID:
43904
Concept ID:
C0021655
Pathologic Function
2.

Insulin

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). [from MeSH]

MedGen UID:
5827
Concept ID:
C0021641
Pharmacologic Substance
3.

Insulin resistance

`Increased resistance` (PATO:0001650) towards `insulin` (PRO:000009054), that is, diminished effectiveness of insulin in reducing blood glucose levels. [from HPO]

MedGen UID:
504630
Concept ID:
CN000801
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