Format

Send to:

Choose Destination

Links from PubMed

Influenza

MedGen UID:
9466
Concept ID:
C0021400
Disease or Syndrome
Synonyms: Flu, Human; Grippe; Human Flu; Human Influenza; Human Influenzas; Influenza in Human; Influenza in Humans; Influenza, Human; Influenzas; Influenzas, Human
SNOMED CT: Influenza (6142004); Flu (6142004); Grippe (6142004)
 
Gene (location): IFITM3 (11p15.5)
OMIM®: 614680

Definition

Flu is a respiratory infection caused by a number of viruses. The viruses pass through the air and enter your body through your nose or mouth. Between 5% and 20% of people in the U.S. get the flu each year. The flu can be serious or even deadly for elderly people, newborn babies, and people with certain chronic illnesses. Symptoms of the flu come on suddenly and are worse than those of the common cold. They may include . -Body or muscle aches. -Chills . -Cough . -Fever . -Headache . -Sore throat . Is it a cold or the flu? Colds rarely cause a fever or headaches. Flu almost never causes an upset stomach. And stomach flu isn't really flu at all, but gastroenteritis. Most people with the flu recover on their own without medical care. People with mild cases of the flu should stay home and avoid contact with others, except to get medical care. If you get the flu, your health care provider may prescribe medicine to help your body fight the infection and lessen symptoms. . The main way to keep from getting the flu is to get a yearly flu vaccine. Good hygiene, including hand washing, can also help. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

Recent clinical studies

Etiology

Caini S, Andrade W, Badur S, Balmaseda A, Barakat A, Bella A, Bimohuen A, Brammer L, Bresee J, Bruno A, Castillo L, Ciblak MA, Clara AW, Cohen C, Cutter J, Daouda C, de Lozano C, De Mora D, Dorji K, Emukule GO, Fasce RA, Feng L, Ferreira de Almeida WA, Guiomar R, Heraud JM, Holubka O, Huang QS, Kadjo HA, Kiyanbekova L, Kosasih H, Kusznierz G, Lara J, Li M, Lopez L, Mai Hoang PV, Pessanha Henriques CM, Matute ML, Mironenko A, Moreno B, Mott JA, Njouom R, Nurhayati, Ospanova A, Owen R, Pebody R, Pennington K, Puzelli S, Quynh Le MT, Razanajatovo NH, Rodrigues A, Rudi JM, Tzer Pin Lin R, Venter M, Vernet MA, Wangchuk S, Yang J, Yu H, Zambon M, Schellevis F, Paget J; Global Influenza B Study
PLoS One 2016;11(3):e0152310. Epub 2016 Mar 31 doi: 10.1371/journal.pone.0152310. PMID: 27031105Free PMC Article
Lafond KE, Nair H, Rasooly MH, Valente F, Booy R, Rahman M, Kitsutani P, Yu H, Guzman G, Coulibaly D, Armero J, Jima D, Howie SR, Ampofo W, Mena R, Chadha M, Sampurno OD, Emukule GO, Nurmatov Z, Corwin A, Heraud JM, Noyola DE, Cojocaru R, Nymadawa P, Barakat A, Adedeji A, von Horoch M, Olveda R, Nyatanyi T, Venter M, Mmbaga V, Chittaganpitch M, Nguyen TH, Theo A, Whaley M, Azziz-Baumgartner E, Bresee J, Campbell H, Widdowson MA; Global Respiratory Hospitalizations—Influenza Proportion Positive (GRIPP) Working Group
PLoS Med 2016 Mar;13(3):e1001977. Epub 2016 Mar 24 doi: 10.1371/journal.pmed.1001977. PMID: 27011229Free PMC Article
Furuse Y, Odagiri T, Tamaki R, Kamigaki T, Otomaru H, Opinion J, Santo A, Dolina-Lacaba D, Daya E, Okamoto M, Saito-Obata M, Inobaya M, Tan A, Tallo V, Lupisan S, Suzuki A, Oshitani H
Virology 2016 May;492:21-4. Epub 2016 Feb 18 doi: 10.1016/j.virol.2016.02.001. [Epub ahead of print] PMID: 26896931
Barr IG, Vijaykrishna D, Sullivan SG
Euro Surveill 2016;21(4) doi: 10.2807/1560-7917.ES.2016.21.4.30118. PMID: 26848118
Benedetti E, Daniels RS, Pontoriero A, Russo M, Avaro M, Czech A, Campos A, Periolo N, Gregory V, McCauley JW, Baumeister EG
Epidemiol Infect 2016 Mar;144(4):751-67. Epub 2015 Sep 8 doi: 10.1017/S0950268815001806. [Epub ahead of print] PMID: 26345289Free PMC Article

Diagnosis

Lee YJ, Jang YH, Kim P, Lee YH, Lee YJ, Byun YH, Lee KH, Kim K, Seong BL
Virology 2016 Apr;491:1-9. Epub 2016 Feb 9 doi: 10.1016/j.virol.2016.01.022. [Epub ahead of print] PMID: 26874012
Campe H, Heinzinger S, Hartberger C, Sing A
Epidemiol Infect 2016 Apr;144(5):1045-51. Epub 2015 Sep 21 doi: 10.1017/S0950268815002228. [Epub ahead of print] PMID: 26388141
van Asten L, Bijkerk P, Fanoy E, van Ginkel A, Suijkerbuijk A, van der Hoek W, Meijer A, Vennema H
Influenza Other Respir Viruses 2016 Jan;10(1):14-26. doi: 10.1111/irv.12348. PMID: 26369646Free PMC Article
Benedetti E, Daniels RS, Pontoriero A, Russo M, Avaro M, Czech A, Campos A, Periolo N, Gregory V, McCauley JW, Baumeister EG
Epidemiol Infect 2016 Mar;144(4):751-67. Epub 2015 Sep 8 doi: 10.1017/S0950268815001806. [Epub ahead of print] PMID: 26345289Free PMC Article
Li-Kim-Moy J, Booy R
Influenza Other Respir Viruses 2016 Jan;10(1):9-13. doi: 10.1111/irv.12337. PMID: 26258888Free PMC Article

Therapy

Lee YJ, Jang YH, Kim P, Lee YH, Lee YJ, Byun YH, Lee KH, Kim K, Seong BL
Virology 2016 Apr;491:1-9. Epub 2016 Feb 9 doi: 10.1016/j.virol.2016.01.022. [Epub ahead of print] PMID: 26874012
Omer SB, Phadke VK, Bednarczyk RA, Chamberlain AT, Brosseau JL, Orenstein WA
J Infect Dis 2016 Apr 15;213(8):1216-23. Epub 2015 Oct 28 doi: 10.1093/infdis/jiv457. [Epub ahead of print] PMID: 26516141Free PMC Article
Savic M, Dembinski JL, Kim Y, Tunheim G, Cox RJ, Oftung F, Peters B, Mjaaland S
Immunology 2016 Feb;147(2):165-77. Epub 2015 Dec 8 doi: 10.1111/imm.12548. [Epub ahead of print] PMID: 26489873Free PMC Article
Wijnans L, Voordouw B
Influenza Other Respir Viruses 2016 Jan;10(1):2-8. doi: 10.1111/irv.12351. PMID: 26439108Free PMC Article
Li-Kim-Moy J, Booy R
Influenza Other Respir Viruses 2016 Jan;10(1):9-13. doi: 10.1111/irv.12337. PMID: 26258888Free PMC Article

Prognosis

Neher RA, Bedford T, Daniels RS, Russell CA, Shraiman BI
Proc Natl Acad Sci U S A 2016 Mar 22;113(12):E1701-9. Epub 2016 Mar 7 doi: 10.1073/pnas.1525578113. [Epub ahead of print] PMID: 26951657Free PMC Article
Viboud C, Simonsen L, Fuentes R, Flores J, Miller MA, Chowell G
J Infect Dis 2016 Mar 1;213(5):738-45. doi: 10.1093/infdis/jiv534. PMID: 26908781Free PMC Article
Savic M, Dembinski JL, Kim Y, Tunheim G, Cox RJ, Oftung F, Peters B, Mjaaland S
Immunology 2016 Feb;147(2):165-77. Epub 2015 Dec 8 doi: 10.1111/imm.12548. [Epub ahead of print] PMID: 26489873Free PMC Article
Campe H, Heinzinger S, Hartberger C, Sing A
Epidemiol Infect 2016 Apr;144(5):1045-51. Epub 2015 Sep 21 doi: 10.1017/S0950268815002228. [Epub ahead of print] PMID: 26388141
Taylor G, Abdesselam K, Pelude L, Fernandes R, Mitchell R, McGeer A, Frenette C, Suh KN, Wong A, Katz K, Wilkinson K, Mersereau T, Gravel D; Canadian Nosocomial Infection Surveillance Program (CNISP)
Epidemiol Infect 2016 Mar;144(4):741-50. Epub 2015 Sep 18 doi: 10.1017/S0950268815002113. [Epub ahead of print] PMID: 26384310Free PMC Article

Clinical prediction guides

Caini S, Andrade W, Badur S, Balmaseda A, Barakat A, Bella A, Bimohuen A, Brammer L, Bresee J, Bruno A, Castillo L, Ciblak MA, Clara AW, Cohen C, Cutter J, Daouda C, de Lozano C, De Mora D, Dorji K, Emukule GO, Fasce RA, Feng L, Ferreira de Almeida WA, Guiomar R, Heraud JM, Holubka O, Huang QS, Kadjo HA, Kiyanbekova L, Kosasih H, Kusznierz G, Lara J, Li M, Lopez L, Mai Hoang PV, Pessanha Henriques CM, Matute ML, Mironenko A, Moreno B, Mott JA, Njouom R, Nurhayati, Ospanova A, Owen R, Pebody R, Pennington K, Puzelli S, Quynh Le MT, Razanajatovo NH, Rodrigues A, Rudi JM, Tzer Pin Lin R, Venter M, Vernet MA, Wangchuk S, Yang J, Yu H, Zambon M, Schellevis F, Paget J; Global Influenza B Study
PLoS One 2016;11(3):e0152310. Epub 2016 Mar 31 doi: 10.1371/journal.pone.0152310. PMID: 27031105Free PMC Article
Schulert GS, Zhang M, Fall N, Husami A, Kissell D, Hanosh A, Zhang K, Davis K, Jentzen JM, Napolitano L, Siddiqui J, Smith LB, Harms PW, Grom AA, Cron RQ
J Infect Dis 2016 Apr 1;213(7):1180-8. Epub 2015 Nov 23 doi: 10.1093/infdis/jiv550. [Epub ahead of print] PMID: 26597256Free PMC Article
Ohmit SE, Petrie JG, Malosh RE, Johnson E, Truscon R, Aaron B, Martens C, Cheng C, Fry AM, Monto AS
J Infect Dis 2016 Apr 15;213(8):1229-36. Epub 2015 Nov 23 doi: 10.1093/infdis/jiv563. [Epub ahead of print] PMID: 26597255Free PMC Article
Savic M, Dembinski JL, Kim Y, Tunheim G, Cox RJ, Oftung F, Peters B, Mjaaland S
Immunology 2016 Feb;147(2):165-77. Epub 2015 Dec 8 doi: 10.1111/imm.12548. [Epub ahead of print] PMID: 26489873Free PMC Article
Caini S, Huang QS, Ciblak MA, Kusznierz G, Owen R, Wangchuk S, Henriques CM, Njouom R, Fasce RA, Yu H, Feng L, Zambon M, Clara AW, Kosasih H, Puzelli S, Kadjo HA, Emukule G, Heraud JM, Ang LW, Venter M, Mironenko A, Brammer L, Mai le TQ, Schellevis F, Plotkin S, Paget J; Global Influenza B Study
Influenza Other Respir Viruses 2015 Aug;9 Suppl 1:3-12. doi: 10.1111/irv.12319. PMID: 26256290Free PMC Article

Recent systematic reviews

Thomas RE, Jefferson T, Lasserson TJ
Cochrane Database Syst Rev 2016 Jun 2;(6):CD005187. doi: 10.1002/14651858.CD005187.pub5. PMID: 27251461
Lafond KE, Nair H, Rasooly MH, Valente F, Booy R, Rahman M, Kitsutani P, Yu H, Guzman G, Coulibaly D, Armero J, Jima D, Howie SR, Ampofo W, Mena R, Chadha M, Sampurno OD, Emukule GO, Nurmatov Z, Corwin A, Heraud JM, Noyola DE, Cojocaru R, Nymadawa P, Barakat A, Adedeji A, von Horoch M, Olveda R, Nyatanyi T, Venter M, Mmbaga V, Chittaganpitch M, Nguyen TH, Theo A, Whaley M, Azziz-Baumgartner E, Bresee J, Campbell H, Widdowson MA; Global Respiratory Hospitalizations—Influenza Proportion Positive (GRIPP) Working Group
PLoS Med 2016 Mar;13(3):e1001977. Epub 2016 Mar 24 doi: 10.1371/journal.pmed.1001977. PMID: 27011229Free PMC Article
Rodrigo C, Leonardi-Bee J, Nguyen-Van-Tam J, Lim WS
Cochrane Database Syst Rev 2016 Mar 7;3:CD010406. doi: 10.1002/14651858.CD010406.pub2. PMID: 26950335
Jackson ML, Bellamy A, Wolff M, Hill H, Jackson LA
Epidemiol Infect 2016 Mar;144(4):768-71. Epub 2015 Sep 2 doi: 10.1017/S0950268815002058. [Epub ahead of print] PMID: 26330204Free PMC Article
Xuan Y, Wang LN, Li W, Zi HR, Guo Y, Yan WJ, Chen XB, Wei PM
Epidemiol Infect 2015 Oct;143(14):2975-84. Epub 2015 Mar 17 doi: 10.1017/S0950268815000278. [Epub ahead of print] PMID: 25778715

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Medical Encyclopedia

    Diseases & Conditions:

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...