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Dengue

MedGen UID:
3721
Concept ID:
C0011311
Disease or Syndrome
Synonyms: Break Bone Fever; Break-Bone Fever; Breakbone Fever; Classical Dengue; Classical Dengue Fever; Classical Dengue Fevers; Classical Dengues; Dengue Fever; Dengue Fever, Classical; Dengue Fevers, Classical; Dengue, Classical; Dengues, Classical; Fever, Break-Bone; Fever, Breakbone; Fever, Dengue
SNOMED CT: Dengue (38362002); Dengue fever (38362002); Breakbone fever (38362002)
 
Orphanet: ORPHA99828

Definition

Dengue is an infection caused by a virus. You can get it if an infected mosquito bites you. Dengue does not spread from person to person. It is common in warm, wet areas of the world. Outbreaks occur in the rainy season. Dengue is rare in the United States. . Symptoms include a high fever, headaches, joint and muscle pain, vomiting, and a rash. In some cases, dengue turns into dengue hemorrhagic fever, which causes bleeding from your nose, gums, or under your skin. It can also become dengue shock syndrome, which causes massive bleeding and shock. These forms of dengue are life-threatening. There is no specific treatment. Most people with dengue recover within 2 weeks. Until then, drinking lots of fluids, resting and taking non-aspirin fever-reducing medicines might help. People with the more severe forms of dengue usually need to go to the hospital and get fluids. To lower your risk when traveling in dengue-prone countries . - Wear insect repellent with DEET . - Wear clothes that cover your arms, legs and feet . - Close unscreened doors and windows . NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGDengue

Recent clinical studies

Etiology

Dinu S, Pănculescu-Gătej IR, Florescu SA, Popescu CP, Sîrbu A, Oprişan G, Bădescu D, Franco L, Ceianu CS
Travel Med Infect Dis 2015 Jan-Feb;13(1):69-73. Epub 2014 Nov 13 doi: 10.1016/j.tmaid.2014.11.001. [Epub ahead of print] PMID: 25468524
Alagarasu K, Bachal RV, Memane RS, Shah PS, Cecilia D
Immunobiology 2015 Jan;220(1):164-8. doi: 10.1016/j.imbio.2014.09.020. PMID: 25446400
Corbett KS, Katzelnick L, Tissera H, Amerasinghe A, de Silva AD, de Silva AM
J Infect Dis 2015 Feb 15;211(4):590-9. Epub 2014 Oct 21 doi: 10.1093/infdis/jiu481. [Epub ahead of print] PMID: 25336728Free PMC Article
Liao CM, Huang TL, Cheng YH, Chen WY, Hsieh NH, Chen SC, Chio CP
Epidemiol Infect 2015 Apr;143(5):1059-72. Epub 2014 Jul 10 doi: 10.1017/S0950268814001745. [Epub ahead of print] PMID: 25007831
Chien LC, Yu HL
Environ Int 2014 Dec;73:46-56. Epub 2014 Jul 31 doi: 10.1016/j.envint.2014.06.018. [Epub ahead of print] PMID: 25084561

Diagnosis

Edillo FE, Halasa YA, Largo FM, Erasmo JN, Amoin NB, Alera MT, Yoon IK, Alcantara AC, Shepard DS
Am J Trop Med Hyg 2015 Feb;92(2):360-6. Epub 2014 Dec 15 doi: 10.4269/ajtmh.14-0139. [Epub ahead of print] PMID: 25510723Free PMC Article
Punyadee N, Mairiang D, Thiemmeca S, Komoltri C, Pan-Ngum W, Chomanee N, Charngkaew K, Tangthawornchaikul N, Limpitikul W, Vasanawathana S, Malasit P, Avirutnan P
J Virol 2015 Feb;89(3):1587-607. Epub 2014 Nov 19 doi: 10.1128/JVI.02207-14. [Epub ahead of print] PMID: 25410854Free PMC Article
Chung SJ, Krishnan PU, Leo YS
Am J Trop Med Hyg 2015 Feb;92(2):367-9. Epub 2014 Nov 10 doi: 10.4269/ajtmh.14-0247. [Epub ahead of print] PMID: 25385858Free PMC Article
Verma R, Sahu R, Holla V
J Neurol Sci 2014 Nov 15;346(1-2):26-34. Epub 2014 Sep 6 doi: 10.1016/j.jns.2014.08.044. [Epub ahead of print] PMID: 25220113
Fuchs I, Bin H, Schlezinger S, Schwartz E
J Med Virol 2014 Dec;86(12):2005-10. Epub 2014 Jan 6 doi: 10.1002/jmv.23879. [Epub ahead of print] PMID: 24390973

Therapy

Thisyakorn U, Thisyakorn C
J Med Assoc Thai 2015 Jan;98 Suppl 1:S118-22. PMID: 25764623
Pandey A, Medlock J
Epidemiol Infect 2015 Apr;143(6):1276-86. Epub 2014 Aug 11 doi: 10.1017/S0950268814001939. [Epub ahead of print] PMID: 25111156
Beesetti H, Khanna N, Swaminathan S
Expert Opin Ther Pat 2014 Nov;24(11):1171-84. Epub 2014 Oct 6 doi: 10.1517/13543776.2014.967212. [Epub ahead of print] PMID: 25283170
Chien LC, Yu HL
Environ Int 2014 Dec;73:46-56. Epub 2014 Jul 31 doi: 10.1016/j.envint.2014.06.018. [Epub ahead of print] PMID: 25084561
Dhar-Chowdhury P, Emdad Haque C, Michelle Driedger S, Hossain S
Int Health 2014 Dec;6(4):306-16. Epub 2014 Jun 30 doi: 10.1093/inthealth/ihu032. [Epub ahead of print] PMID: 24981443

Prognosis

Pandey N, Jain A, Garg RK, Kumar R, Agrawal OP, Lakshmana Rao PV
Arch Virol 2015 Jun;160(6):1463-75. Epub 2015 Apr 10 doi: 10.1007/s00705-015-2410-6. [Epub ahead of print] PMID: 25860648
Alagarasu K, Bachal RV, Memane RS, Shah PS, Cecilia D
Immunobiology 2015 Jan;220(1):164-8. doi: 10.1016/j.imbio.2014.09.020. PMID: 25446400
Punyadee N, Mairiang D, Thiemmeca S, Komoltri C, Pan-Ngum W, Chomanee N, Charngkaew K, Tangthawornchaikul N, Limpitikul W, Vasanawathana S, Malasit P, Avirutnan P
J Virol 2015 Feb;89(3):1587-607. Epub 2014 Nov 19 doi: 10.1128/JVI.02207-14. [Epub ahead of print] PMID: 25410854Free PMC Article
Pandey A, Medlock J
Epidemiol Infect 2015 Apr;143(6):1276-86. Epub 2014 Aug 11 doi: 10.1017/S0950268814001939. [Epub ahead of print] PMID: 25111156
Liao CM, Huang TL, Cheng YH, Chen WY, Hsieh NH, Chen SC, Chio CP
Epidemiol Infect 2015 Apr;143(5):1059-72. Epub 2014 Jul 10 doi: 10.1017/S0950268814001745. [Epub ahead of print] PMID: 25007831

Clinical prediction guides

Pandey N, Jain A, Garg RK, Kumar R, Agrawal OP, Lakshmana Rao PV
Arch Virol 2015 Jun;160(6):1463-75. Epub 2015 Apr 10 doi: 10.1007/s00705-015-2410-6. [Epub ahead of print] PMID: 25860648
Alagarasu K, Bachal RV, Memane RS, Shah PS, Cecilia D
Immunobiology 2015 Jan;220(1):164-8. doi: 10.1016/j.imbio.2014.09.020. PMID: 25446400
Punyadee N, Mairiang D, Thiemmeca S, Komoltri C, Pan-Ngum W, Chomanee N, Charngkaew K, Tangthawornchaikul N, Limpitikul W, Vasanawathana S, Malasit P, Avirutnan P
J Virol 2015 Feb;89(3):1587-607. Epub 2014 Nov 19 doi: 10.1128/JVI.02207-14. [Epub ahead of print] PMID: 25410854Free PMC Article
Corbett KS, Katzelnick L, Tissera H, Amerasinghe A, de Silva AD, de Silva AM
J Infect Dis 2015 Feb 15;211(4):590-9. Epub 2014 Oct 21 doi: 10.1093/infdis/jiu481. [Epub ahead of print] PMID: 25336728Free PMC Article
Pandey A, Medlock J
Epidemiol Infect 2015 Apr;143(6):1276-86. Epub 2014 Aug 11 doi: 10.1017/S0950268814001939. [Epub ahead of print] PMID: 25111156

Recent systematic reviews

Lazaro A, Han WW, Manrique-Saide P, George L, Velayudhan R, Toledo J, Runge Ranzinger S, Horstick O
Trop Med Int Health 2015 Jun;20(6):685-706. Epub 2015 Mar 22 doi: 10.1111/tmi.12485. [Epub ahead of print] PMID: 25708814
Louis VR, Phalkey R, Horstick O, Ratanawong P, Wilder-Smith A, Tozan Y, Dambach P
Int J Health Geogr 2014 Dec 9;13:50. doi: 10.1186/1476-072X-13-50. [Epub ahead of print] PMID: 25487167Free PMC Article
da Costa VG, Marques-Silva AC, Floriano VG, Moreli ML
Vaccine 2014 Sep 3;32(39):4885-92. Epub 2014 Jul 19 doi: 10.1016/j.vaccine.2014.07.008. [Epub ahead of print] PMID: 25045816
Horstick O, Jaenisch T, Martinez E, Kroeger A, See LL, Farrar J, Ranzinger SR
Am J Trop Med Hyg 2014 Sep;91(3):621-34. Epub 2014 Jun 23 doi: 10.4269/ajtmh.13-0676. [Epub ahead of print] PMID: 24957540Free PMC Article
Runge-Ranzinger S, McCall PJ, Kroeger A, Horstick O
Trop Med Int Health 2014 Sep;19(9):1116-60. Epub 2014 May 28 doi: 10.1111/tmi.12333. [Epub ahead of print] PMID: 24889501Free PMC Article

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