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1.

Malignant Neoplasm

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body. . Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, biologic therapy, or stem cell transplantation. . NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
14297
Concept ID:
C0006826
Neoplastic Process
2.

Carcinogenesis

The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. [from MeSH]

MedGen UID:
154544
Concept ID:
C0596263
Neoplastic Process
3.

Glioblastoma

a type of brain tumor [from CHV]

MedGen UID:
42228
Concept ID:
C0017636
Neoplastic Process
4.

Malignant melanoma

Melanoma is the most serious type of skin cancer. Often the first sign of melanoma is a change in the size, shape, color, or feel of a mole. Most melanomas have a black or black-blue area. Melanoma may also appear as a new mole. It may be black, abnormal, or ugly looking.. Thinking of ABCDE can help you remember what to watch for:: - Asymmetry - the shape of one half does not match the other. - Border - the edges are ragged, blurred or irregular. - Color - the color is uneven and may include shades of black, brown and tan. - Diameter - there is a change in size, usually an increase. -Evolving - the mole has changed over the past few weeks or months. Surgery is the first treatment of all stages of melanoma. Other treatments include chemotherapy and radiation, biologic, and targeted therapies. Biologic therapy boosts your body's own ability to fight cancer. Targeted therapy uses substances that attack cancer cells without harming normal cells. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
9944
Concept ID:
C0025202
Neoplastic Process
5.

Diagnosis

The process of identifying a disease, such as cancer, from its signs and symptoms. [from NCI]

MedGen UID:
8354
Concept ID:
C0011900
Finding
6.

Glioblastoma

MedGen UID:
832786
Concept ID:
CN227279
Disease or Syndrome
7.

Poor prognosis

MedGen UID:
548766
Concept ID:
C0278252
Finding
8.

Glioblastoma

MedGen UID:
506549
Concept ID:
CN117732
Finding
9.

Melanoma

The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea). [from HPO]

MedGen UID:
505377
Concept ID:
CN002586
Finding
10.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
11.

Analgesics, Non-Narcotic

A subclass of analgesic agents that typically do not bind to OPIOID RECEPTORS and are not addictive. Many non-narcotic analgesics are offered as NONPRESCRIPTION DRUGS. [from MeSH]

MedGen UID:
69295
Concept ID:
C0242937
Pharmacologic Substance
12.

Sensory System Agents

Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367) [from MeSH]

MedGen UID:
67054
Concept ID:
C0243058
Pharmacologic Substance
13.

Peripheral Nervous System Agents

Drugs that act principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. (From Smith and Reynard, Textbook of Pharmacology, 1991, p75) [from MeSH]

MedGen UID:
67048
Concept ID:
C0243049
Pharmacologic Substance
14.

Neoplasm

A general term for autonomous tissue growth in which the malignancy status has not been established and for which the transformed cell type has not been specifically identified. [from NCI]

MedGen UID:
10294
Concept ID:
C0027651
Neoplastic Process
15.

Analgesics, Anti-Inflammatory

MedGen UID:
8050
Concept ID:
C0002773
Pharmacologic Substance
16.

Analgesics

Pain relievers are medicines that reduce or relieve headaches, sore muscles, arthritis or any number of other aches and pains. There are many different pain medicines, and each one has advantages and risks. Some types of pain respond better to certain medicines than others. Each person may also have a slightly different response to a pain reliever. . Over-the-counter (OTC) medicines are good for many types of pain. There are two main types of OTC pain medications: acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin, naproxen (Aleve) and ibuprofen (Advil, Motrin) are examples of OTC NSAIDs. If OTC medicines don't relieve your pain, your doctor may prescribe something stronger. Many NSAIDs are available at prescription doses. The most powerful pain relievers are narcotics. They are very effective, but they can sometimes have serious side effects. Because of the risks, you must use them only under a doctor's supervision. There are many things you can do to help ease pain. Pain relievers are just one part of a pain treatment plan.  [from MedlinePlus]

MedGen UID:
8049
Concept ID:
C0002771
Pharmacologic Substance
17.

Anti-Inflammatory Agents

agent that counteracts or suppresses the inflammatory process. [from CRISP]

MedGen UID:
1574
Concept ID:
C0003209
Pharmacologic Substance
18.

Anti-Inflammatory Agents, Non-Steroidal

A group of drugs that decrease fever, swelling, pain, and redness. [from NCI]

MedGen UID:
326
Concept ID:
C0003211
Pharmacologic Substance
19.

Antirheumatic Agents

agent that relieves or prevents rheumatic disease, especially rheumatoid arthritis. [from CRISP]

MedGen UID:
323
Concept ID:
C0003191
Pharmacologic Substance
20.

Inflammatory disorder of breast

MedGen UID:
758769
Concept ID:
C3495439
Disease or Syndrome

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