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Results: 1 to 20 of 40

1.

Neurodegeneration

MedGen UID:
506929
Concept ID:
CN178344
Disease or Syndrome
2.

Neurodegeneration

Progressive loss of neural cells and tissue. [from HPO]

MedGen UID:
505144
Concept ID:
CN001976
Finding
3.

The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. [from MeSH]

MedGen UID:
154544
Concept ID:
C0596263
4.

MedGen UID:
110960
Concept ID:
C0210504
5.

Oxidative Stress

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi). [from MeSH]

MedGen UID:
66929
Concept ID:
C0242606
Cell or Molecular Dysfunction
6.

Oxygen

An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. [from MeSH]

MedGen UID:
45267
Concept ID:
C0030054
Pharmacologic Substance
7.

Strand breaks

MedGen UID:
549441
Concept ID:
C0301647
Molecular Function
8.

Visual Suppression

MedGen UID:
526147
Concept ID:
C0221103
Pathologic Function
9.

Mitochondrial inheritance

A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy). [from HPO]

MedGen UID:
504838
Concept ID:
CN001305
Finding
10.

Neuronal loss in central nervous system

MedGen UID:
342515
Concept ID:
C1850496
Finding
11.

Spondylometaepiphyseal dysplasia short limb-hand type

MedGen UID:
338595
Concept ID:
C1849011
Disease or Syndrome
12.

MedGen UID:
109303
Concept ID:
C0596988
13.

Severe

A term used to describe cells that look abnormal under a microscope. These cells are more likely to grow and spread quickly than cells in low-grade cancer or in growths that may become cancer. [from NCI]

MedGen UID:
104640
Concept ID:
C0205082
14.

Lesion

An area of abnormal tissue. A lesion may be benign (not cancer) or malignant (cancer). [from NCI]

MedGen UID:
65128
Concept ID:
C0221198
Finding
15.

Stress

The response of the body to physical, mental, or emotional pressure. This may make a person feel frustrated, angry, or anxious, and may cause unhealthy chemical changes in the body. Untreated, long-term stress may lead to many types of mental and physical health problems. [from NCI]

MedGen UID:
20971
Concept ID:
C0038435
Finding
16.

Endoglycosidases

MedGen UID:
760845
Concept ID:
C3537242
Pharmacologic Substance
17.

DNA Breaks

Interruptions in the sugar-phosphate backbone of DNA. [from MeSH]

MedGen UID:
354581
Concept ID:
C1721104
Molecular Function
18.

DNA Breaks, Single-Stranded

Interruptions in one of the strands of the sugar-phosphate backbone of double-stranded DNA. [from MeSH]

MedGen UID:
307403
Concept ID:
C1511698
Cell or Molecular Dysfunction
19.

Biochemical Processes

Chemical reactions or functions, enzymatic activities, and metabolic pathways of living things. [from MeSH]

MedGen UID:
267723
Concept ID:
C1511130
Molecular Function
20.

MedGen UID:
108834
Concept ID:
C0591833

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