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Results: 3

1.

Canakinumab

A recombinant monoclonal antibody targeting human interleukin-1 beta (IL-1b), with anti-inflammatory and immunomodulating activities. Canakinumab binds IL-1b and prevents the binding of IL-1b to the IL-1 receptor and inhibits IL-1b-mediated signaling. This may suppress inflammatory responses mediated by IL-1b. IL-1b, a proinflammatory cytokine, plays a key role in inflammation. [from NCI]

MedGen UID:
439367
Concept ID:
C2718773
Pharmacologic Substance
2.

Fibrinogen

A fibrillar protein present in blood plasma; it converts to fibrin during the process of blood clot formation. [from NCI]

MedGen UID:
8832
Concept ID:
C0016006
Pharmacologic Substance
3.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function

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