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Results: 9

1.

nabilone

A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39760&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39760&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1171" NCI Thesaurus) [from PDQ]

MedGen UID:
74055
Concept ID:
C0068333
Pharmacologic Substance
2.

Pain

Unpleasant sensory and emotional experience associated with actual or potential tissue damage. [from OMS]

MedGen UID:
45282
Concept ID:
C0030193
Sign or Symptom
3.

Pain

MedGen UID:
776584
Concept ID:
C2364139
Finding
4.

Peripheral neuropathic pain

MedGen UID:
631304
Concept ID:
C0458960
Sign or Symptom
5.

Withdrawal (dysfunction)

A social or emotional detachment, pathological retreat from objective reality, interpersonal contact and social involvement, as in some forms of schizophrenia, depression, or schizoid, avoidant, or schizotypal personality disorders. [from NCI]

MedGen UID:
442895
Concept ID:
C2825032
Mental or Behavioral Dysfunction
6.

Neuralgia

A disorder characterized by intense painful sensation along a nerve or group of nerves. [from NCI]

MedGen UID:
18010
Concept ID:
C0027796
Sign or Symptom
7.

MedGen UID:
182423
Concept ID:
C0917774
8.

MedGen UID:
152583
Concept ID:
C0728767
9.

Patient status

MedGen UID:
623026
Concept ID:
C0449437
Finding

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