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Results: 8

1.

Hypopituitarism

Diminution or cessation of secretion of one or more hormones from the anterior pituitary gland (including LH; FOLLICLE STIMULATING HORMONE; SOMATOTROPIN; and CORTICOTROPIN). This may result from surgical or radiation ablation, non-secretory PITUITARY NEOPLASMS, metastatic tumors, infarction, PITUITARY APOPLEXY, infiltrative or granulomatous processes, and other conditions. [from MeSH]

MedGen UID:
9386
Concept ID:
C0020635
Disease or Syndrome
2.

Autoimmune state

Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES. [from MeSH]

MedGen UID:
2136
Concept ID:
C0004368
Pathologic Function
3.

Autoimmunity

The occurrence of an immune reaction against the organisms own cells or tissues. [from HPO]

MedGen UID:
505423
Concept ID:
CN002679
Finding
4.

Autoimmune reaction

A specific humoral or cell-mediated immune response against autologous (self) antigens. An autoimmune process may produce or be caused by autoimmune disease and may be developmentally complex, not necessarily pathological, and possibly pervasive. [from NCI]

MedGen UID:
105217
Concept ID:
C0443146
Pathologic Function
5.

Hypophysitis

MedGen UID:
575012
Concept ID:
C0342409
Disease or Syndrome
6.

Adrenocorticotropic hormone deficiency

A reduced ability to secrete adrenocorticotropic hormone (ACTH), a hormone that stimulates the adrenal cortex to secrete of glucocorticoids such as cortisol. [from HPO]

MedGen UID:
506613
Concept ID:
CN167476
Finding
7.

Central diabetes insipidus

A form of diabetes insipidus related to a failure of vasopressin (AVP) release from the hypothalamus. [from HPO]

MedGen UID:
504634
Concept ID:
CN000809
Finding
8.

ACTH deficiency

Congenital isolated adrenocorticotropic hormone deficiency is characterized by severe hypoglycemia in the neonatal period, associated with seizures in about half of cases; prolonged cholestatic jaundice; and very low plasma ACTH levels with no significant response to CRH (122560). Plasma cortisol levels are also extremely low (Vallette-Kasic et al., 2005). TBX19 is required for initiation of transcription of the POMC gene (176830), which produces the precursor peptide from which ACTH is derived (Lamolet et al., 2001). [from OMIM]

MedGen UID:
137968
Concept ID:
C0342388
Disease or Syndrome

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