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Results: 7

1.

PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, SEVERE EARLY-ONSET

MedGen UID:
376022
Concept ID:
C1847014
Disease or Syndrome
2.

Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality. COPD is defined by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. Airflow obstruction is typically determined by reductions in quantitative spirometric indices, including forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) (Silverman et al., 2002; Celedon et al., 2004). [from OMIM]

MedGen UID:
9818
Concept ID:
C0024117
Disease or Syndrome
3.

Aging

Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999). [from OMIM]

MedGen UID:
1376
Concept ID:
C0001811
4.

Chronic obstructive pulmonary disease

MedGen UID:
505916
Concept ID:
CN005670
Finding
5.

Premature aging syndrome

Changes in the organism associated with senescence, occurring at an accelerated rate. [from MeSH]

MedGen UID:
65416
Concept ID:
C0231341
Disease or Syndrome
6.

Disorder of lung

When you breathe, your lungs take in oxygen from the air and deliver it to the bloodstream. The cells in your body need oxygen to work and grow. During a normal day, you breathe nearly 25,000 times. People with lung disease have difficulty breathing. Millions of people in the U.S. have lung disease. If all types of lung disease are lumped together, it is the number three killer in the United States. The term lung disease refers to many disorders affecting the lungs, such as asthma, COPD, infections like influenza, pneumonia and tuberculosis, lung cancer, and many other breathing problems. Some lung diseases can lead to respiratory failure. Dept. of Health and Human Services Office on Women's Health.  [from MedlinePlus]

MedGen UID:
7399
Concept ID:
C0024115
Disease or Syndrome
7.

Glucocorticoid therapy, response to

MedGen UID:
482319
Concept ID:
C3280689
Disease or Syndrome

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