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Results: 18

1.

Vaccines, DNA

Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers. [from MeSH]

MedGen UID:
138230
Concept ID:
C0376613
Pharmacologic Substance
2.

Vaccines

Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. Vaccines range from inactivated or attenuated microorganisms (bacteria and viruses), enhanced autologous tumor cells, tumor antigens or epitopes that are used to elicit host immune responses. Vaccines are used for the prevention, amelioration, or treatment of infectious diseases and cancer. [from NCI]

MedGen UID:
52963
Concept ID:
C0042210
Pharmacologic Substance
3.

Infection

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. [from MeSH]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
4.

Infection

Unknown contamination with disease-producing germs. [from HHCC]

MedGen UID:
43874
Concept ID:
C0021311
Disease or Syndrome
5.

Tuberculosis

Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. . TB spreads through the air when a person with TB of the lungs or throat coughs, sneezes, or talks. If you have been exposed, you should go to your doctor for tests. You are more likely to get TB if you have a weak immune system. Symptoms of TB in the lungs may include: - A bad cough that lasts 3 weeks or longer. - Weight loss. - Loss of appetite. - Coughing up blood or mucus. - Weakness or fatigue . - Fever. - Night sweats. Skin tests, blood tests, x-rays, and other tests can tell if you have TB. If not treated properly, TB can be deadly. You can usually cure active TB by taking several medicines for a long period of time. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
22513
Concept ID:
C0041296
Disease or Syndrome
6.

Immune status

Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances. [from MeSH]

MedGen UID:
9426
Concept ID:
C0020964
Finding
7.

Malaria

Malaria is a serious disease caused by a parasite. You get it when an infected mosquito bites you. Malaria is a major cause of death worldwide, but it is almost wiped out in the United States. The disease is mostly a problem in developing countries with warm climates. If you travel to these countries, you are at risk. There are four different types of malaria caused by four related parasites. The most deadly type occurs in Africa south of the Sahara Desert. Malaria symptoms include chills, flu-like symptoms, fever, vomiting, diarrhea, and jaundice. A blood test can diagnose it. It can be life-threatening. However, you can treat malaria with drugs. The type of drug depends on which kind of malaria you have and where you were infected. Malaria can be prevented. When traveling to malaria-prone regions: - See your doctor for medicines that protect you . - Wear insect repellent with DEET . - Cover up. - Sleep under mosquito netting . Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
8.

Inflammation

A microscopic finding indicating the presence of acute, subacute or chronic inflammation in a tissue sample. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
9.

Influenza

Flu is a respiratory infection caused by a number of viruses. The viruses pass through the air and enter your body through your nose or mouth. Between 5% and 20% of people in the U.S. get the flu each year. The flu can be serious or even deadly for elderly people, newborn babies, and people with certain chronic illnesses. Symptoms of the flu come on suddenly and are worse than those of the common cold. They may include: -Body or muscle aches. -Chills . -Cough . -Fever . -Headache . -Sore throat . Is it a cold or the flu? Colds rarely cause a fever or headaches. Flu almost never causes an upset stomach. And stomach flu isn't really flu at all, but gastroenteritis. Most people with the flu recover on their own without medical care. People with mild cases of the flu should stay home and avoid contact with others, except to get medical care. If you get the flu, your health care provider may prescribe medicine to help your body fight the infection and lessen symptoms. . The main way to keep from getting the flu is to get a yearly flu vaccine. Good hygiene, including hand washing, can also help. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
9466
Concept ID:
C0021400
Disease or Syndrome
10.

Human immunodeficiency virus infection

An infection caused by the human immunodeficiency virus. [from NCI]

MedGen UID:
5583
Concept ID:
C0019693
Disease or Syndrome
11.

Murine

MedGen UID:
108834
Concept ID:
C0591833
Pharmacologic Substance
12.

Injectable Drugs

A drug or medicine that can be injected [from CHV]

MedGen UID:
88572
Concept ID:
C0086466
Pharmacologic Substance
13.

Vaccines, Synthetic

Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified. [from MeSH]

MedGen UID:
22601
Concept ID:
C0042213
Pharmacologic Substance
14.

Artificial antigen

small synthetic peptides that mimic surface antigens of pathogens and are immunogenic. [from CRISP]

MedGen UID:
11692
Concept ID:
C0039115
Pharmacologic Substance
15.

Vaccines, Recombinant

MedGen UID:
11144
Concept ID:
C0034862
Pharmacologic Substance
16.

Diagnosis

The process of identifying a disease, such as cancer, from its signs and symptoms. [from NCI]

MedGen UID:
8354
Concept ID:
C0011900
Finding
17.

Biological Products

Complex pharmaceutical substances, preparations, or agents of organic origin, usually obtained by biological methods or assay. They are used especially in diagnosis and treatment of disease (as vaccines or pollen extracts). Biological products are differentiated from BIOLOGICAL FACTORS in that the latter are compounds with biological or physiological activity made by living organisms. (From Webster's 3d ed) [from MeSH]

MedGen UID:
577
Concept ID:
C0005522
Pharmacologic Substance
18.

Synchrotope TA2M plasmid DNA vaccine

A recombinant plasmid DNA vaccine encoding epitopes of tyrosinase with potential antineoplastic activity. Synchrotope TA2M vaccine contains a plasmid encoding 2 epitopes, amino acid sequences 207-216 and 1-17 of tyrosinase, a protein frequently expressed by melanoma cells. Vaccination with the TA2M plasmid DNA vaccine may induce the production of anti-tyrosinase antibodies as well as elicit a cytotoxic T-lymphocyte (CTL) response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth. [from NCI]

MedGen UID:
209495
Concept ID:
C1134471
Pharmacologic Substance

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