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Rabies

MedGen UID:
48308
Concept ID:
C0034494
Disease or Syndrome
Synonyms: Hydrophobia; Lyssa; Lyssas
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Describes a disorder that is not inherited.
SNOMED CT: Rabies (14168008); Hydrophobia (14168008); Lyssa (14168008)
 
Orphanet: ORPHA770

Definition

Rabies is a deadly animal disease caused by a virus. It can happen in wild animals, including raccoons, skunks, bats and foxes, or in dogs, cats or farm animals. People get it from the bite of an infected animal. . In people, symptoms of rabies include fever, headache and fatigue, then confusion, hallucinations and paralysis. Once the symptoms begin, the disease is usually fatal. A series of shots can prevent rabies in people exposed to the virus. You need to get them right away. If an animal bites you, wash the wound well; then get medical care. . To help prevent rabies. - Vaccinate your pet. Rabies vaccines are available for dogs, cats and farm animals. - Don't let pets roam. - Don't approach stray animals. Animals with rabies might be aggressive and vicious, or tired and weak. Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

Recent clinical studies

Etiology

Servat A, Kempff S, Brogat V, Litaize E, Schereffer JL, Cliquet F
Altern Lab Anim 2015 Mar;43(1):19-27. PMID: 25802995
Tantawichien T, Sibunruang S, Tantawichien T, Angsanakul J, Benjavongkulchai M, Limsuwan K, Udomchaisakul P, Khomvilai S, Sitprija V
Expert Rev Vaccines 2014 Dec;13(12):1593-601. Epub 2014 Oct 15 doi: 10.1586/14760584.2014.971764. [Epub ahead of print] PMID: 25315021
Sari T, Tulek N, Bulut C, Oral B, Tuncer Ertem G
Travel Med Infect Dis 2014 Nov-Dec;12(6 Pt A):659-66. Epub 2014 Mar 18 doi: 10.1016/j.tmaid.2014.03.004. [Epub ahead of print] PMID: 24685372
Wallace RM, Stanek D, Griese S, Krulak D, Vora NM, Pacha L, Kan V, Said M, Williams C, Burgess TH, Clausen SS, Austin C, Gabel J, Lehman M, Finelli LN, Selvaggi G, Joyce P, Gordin F, Benator D, Bettano A, Cersovsky S, Blackmore C, Jones SV, Buchanan BD, Fernandez AI, Dinelli D, Agnes K, Clark A, Gill J, Irmler M, Blythe D, Mitchell K, Whitman TJ, Zapor MJ, Zorich S, Witkop C, Jenkins P, Mora P, Droller D, Turner S, Dunn L, Williams P, Richards C, Ewing G, Chapman K, Corbitt C, Girimont T, Franka R, Recuenco S, Blanton JD, Feldman KA
Zoonoses Public Health 2014 Dec;61(8):560-70. Epub 2014 Mar 27 doi: 10.1111/zph.12105. [Epub ahead of print] PMID: 24673934
Farahtaj F, Fayaz A, Howaizi N, Biglari P, Gholami A
Trop Doct 2014 Oct;44(4):226-9. Epub 2014 Mar 24 doi: 10.1177/0049475514528174. [Epub ahead of print] PMID: 24662365

Diagnosis

Servat A, Kempff S, Brogat V, Litaize E, Schereffer JL, Cliquet F
Altern Lab Anim 2015 Mar;43(1):19-27. PMID: 25802995
Feng Y, Wang W, Guo J, Alatengheli, Li Y, Yang G, Su N, Zhang L, Xu W, Sheng Z, Ma L, Gui J, Dejide, Lin H, Tu C
Epidemiol Infect 2015 Apr;143(6):1287-91. Epub 2014 Jul 31 doi: 10.1017/S0950268814001952. [Epub ahead of print] PMID: 25078967
Wallace RM, Stanek D, Griese S, Krulak D, Vora NM, Pacha L, Kan V, Said M, Williams C, Burgess TH, Clausen SS, Austin C, Gabel J, Lehman M, Finelli LN, Selvaggi G, Joyce P, Gordin F, Benator D, Bettano A, Cersovsky S, Blackmore C, Jones SV, Buchanan BD, Fernandez AI, Dinelli D, Agnes K, Clark A, Gill J, Irmler M, Blythe D, Mitchell K, Whitman TJ, Zapor MJ, Zorich S, Witkop C, Jenkins P, Mora P, Droller D, Turner S, Dunn L, Williams P, Richards C, Ewing G, Chapman K, Corbitt C, Girimont T, Franka R, Recuenco S, Blanton JD, Feldman KA
Zoonoses Public Health 2014 Dec;61(8):560-70. Epub 2014 Mar 27 doi: 10.1111/zph.12105. [Epub ahead of print] PMID: 24673934
Farahtaj F, Fayaz A, Howaizi N, Biglari P, Gholami A
Trop Doct 2014 Oct;44(4):226-9. Epub 2014 Mar 24 doi: 10.1177/0049475514528174. [Epub ahead of print] PMID: 24662365
Mani RS, Madhusudana SN, Mahadevan A, Reddy V, Belludi AY, Shankar SK
J Med Virol 2014 Oct;86(10):1804-12. Epub 2013 Oct 17 doi: 10.1002/jmv.23814. [Epub ahead of print] PMID: 24136727

Therapy

Huang Y, Chen Z, Huang J, Fu Z, He B
J Virol 2015 Mar;89(6):3427-9. Epub 2014 Dec 31 doi: 10.1128/JVI.03656-14. [Epub ahead of print] PMID: 25552723Free PMC Article
Tsiodras S, Korou LM, Tzani M, Tasioudi KE, Kalachanis K, Mangana-Vougiouka O, Rigakos G, Dougas G, Seimenis AM, Kontos V
Travel Med Infect Dis 2014 Nov-Dec;12(6 Pt A):628-35. Epub 2014 Oct 23 doi: 10.1016/j.tmaid.2014.10.013. [Epub ahead of print] PMID: 25459432
Tantawichien T, Sibunruang S, Tantawichien T, Angsanakul J, Benjavongkulchai M, Limsuwan K, Udomchaisakul P, Khomvilai S, Sitprija V
Expert Rev Vaccines 2014 Dec;13(12):1593-601. Epub 2014 Oct 15 doi: 10.1586/14760584.2014.971764. [Epub ahead of print] PMID: 25315021
Wallace RM, Stanek D, Griese S, Krulak D, Vora NM, Pacha L, Kan V, Said M, Williams C, Burgess TH, Clausen SS, Austin C, Gabel J, Lehman M, Finelli LN, Selvaggi G, Joyce P, Gordin F, Benator D, Bettano A, Cersovsky S, Blackmore C, Jones SV, Buchanan BD, Fernandez AI, Dinelli D, Agnes K, Clark A, Gill J, Irmler M, Blythe D, Mitchell K, Whitman TJ, Zapor MJ, Zorich S, Witkop C, Jenkins P, Mora P, Droller D, Turner S, Dunn L, Williams P, Richards C, Ewing G, Chapman K, Corbitt C, Girimont T, Franka R, Recuenco S, Blanton JD, Feldman KA
Zoonoses Public Health 2014 Dec;61(8):560-70. Epub 2014 Mar 27 doi: 10.1111/zph.12105. [Epub ahead of print] PMID: 24673934
Farahtaj F, Fayaz A, Howaizi N, Biglari P, Gholami A
Trop Doct 2014 Oct;44(4):226-9. Epub 2014 Mar 24 doi: 10.1177/0049475514528174. [Epub ahead of print] PMID: 24662365

Prognosis

Shankaraiah RH, Rajashekar RA, Veena V, Hanumanthaiah AN
Indian J Public Health 2015 Jan-Mar;59(1):58-60. doi: 10.4103/0019-557X.152867. PMID: 25758734
Muyila DI, Aloni MN, Lose-Ekanga MJ, Nzita JM, Kalala-Mbikay A, Bongo HL, Esako MN, Malonga-Biapi JP, Mputu-Dibwe B, Aloni ML, Ekila MB
Pathog Glob Health 2014 Oct;108(7):317-22. doi: 10.1179/2047773214Y.0000000161. PMID: 25417907Free PMC Article
Sittichanbuncha Y, Chairat C, Sawanyawisuth K, Senthong V
Southeast Asian J Trop Med Public Health 2014 Sep;45(5):1048-52. PMID: 25417505
Kashino W, Piyaphanee W, Kittitrakul C, Tangpukdee N, Sibunruang S, Lawpoolsri S, Yamashita H, Muangnoicharoen S, Silachamroon U, Tantawichien T
J Travel Med 2014 Jul-Aug;21(4):240-7. Epub 2014 May 20 doi: 10.1111/jtm.12124. [Epub ahead of print] PMID: 24845015
Bottoms K, Trotz-Williams L, Hutchison S, MacLeod J, Dixon J, Berke O, Poljak Z
Zoonoses Public Health 2014 Nov;61(7):499-508. Epub 2014 Mar 13 doi: 10.1111/zph.12101. [Epub ahead of print] PMID: 24628865

Clinical prediction guides

Muyila DI, Aloni MN, Lose-Ekanga MJ, Nzita JM, Kalala-Mbikay A, Bongo HL, Esako MN, Malonga-Biapi JP, Mputu-Dibwe B, Aloni ML, Ekila MB
Pathog Glob Health 2014 Oct;108(7):317-22. doi: 10.1179/2047773214Y.0000000161. PMID: 25417907Free PMC Article
Sittichanbuncha Y, Chairat C, Sawanyawisuth K, Senthong V
Southeast Asian J Trop Med Public Health 2014 Sep;45(5):1048-52. PMID: 25417505
Tantawichien T, Sibunruang S, Tantawichien T, Angsanakul J, Benjavongkulchai M, Limsuwan K, Udomchaisakul P, Khomvilai S, Sitprija V
Expert Rev Vaccines 2014 Dec;13(12):1593-601. Epub 2014 Oct 15 doi: 10.1586/14760584.2014.971764. [Epub ahead of print] PMID: 25315021
Bottoms K, Trotz-Williams L, Hutchison S, MacLeod J, Dixon J, Berke O, Poljak Z
Zoonoses Public Health 2014 Nov;61(7):499-508. Epub 2014 Mar 13 doi: 10.1111/zph.12101. [Epub ahead of print] PMID: 24628865
Davlin SL, Lapiz SM, Miranda ME, Murray KO
Epidemiol Infect 2014 Jul;142(7):1476-85. Epub 2013 Oct 7 doi: 10.1017/S0950268813002513. [Epub ahead of print] PMID: 24093635

Recent systematic reviews

Tsiodras S, Korou LM, Tzani M, Tasioudi KE, Kalachanis K, Mangana-Vougiouka O, Rigakos G, Dougas G, Seimenis AM, Kontos V
Travel Med Infect Dis 2014 Nov-Dec;12(6 Pt A):628-35. Epub 2014 Oct 23 doi: 10.1016/j.tmaid.2014.10.013. [Epub ahead of print] PMID: 25459432
Morters MK, Restif O, Hampson K, Cleaveland S, Wood JL, Conlan AJ
J Anim Ecol 2013 Jan;82(1):6-14. Epub 2012 Sep 24 doi: 10.1111/j.1365-2656.2012.02033.x. [Epub ahead of print] PMID: 23004351Free PMC Article
Kakkar M, Venkataramanan V, Krishnan S, Chauhan RS, Abbas SS; Roadmap to Combat Zoonoses in India (RCZI) initiative
PLoS Negl Trop Dis 2012;6(8):e1748. Epub 2012 Aug 7 doi: 10.1371/journal.pntd.0001748. PMID: 22880139Free PMC Article
Davlin SL, Vonville HM
Vaccine 2012 May 21;30(24):3492-502. Epub 2012 Apr 3 doi: 10.1016/j.vaccine.2012.03.069. [Epub ahead of print] PMID: 22480924
Centers for Disease Control and Prevention
Ann Emerg Med 2010 Jul;56(1):64-7. PMID: 20648715

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