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Results: 11

1.

Insulin Glargine

A recombinant human insulin analog with long-acting, blood glucose-lowering activity. Insulin glargine, like regular types of human insulin, regulates glucose metabolism by binding to insulin receptors on muscle and fat cells, thereby facilitating the cellular uptake of glucose. This lowers blood glucose levels. At the same time, insulin glargine inhibits the liver's conversion of stored glycogen into glucose, which also contributes to lower blood glucose levels. Insulin glargine also inhibits lipolysis in adipose tissue, inhibits proteolysis, and enhances protein synthesis. (NCI05) [from NCI]

MedGen UID:
172793
Concept ID:
C0907402
Pharmacologic Substance
2.

Insulin

A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). [from MeSH]

MedGen UID:
5827
Concept ID:
C0021641
Pharmacologic Substance
3.

Hyperglycemia

Hyperglycemia means high blood sugar or glucose. Glucose comes from the foods you eat. Insulin is a hormone that moves glucose into your cells to give them energy. Hyperglycemia happens when your body doesn't make enough insulin or can't use it the right way. People with diabetes can get hyperglycemia from not eating the right foods or not taking medicines correctly. Other problems that can raise blood sugar include infections, certain medicines, hormone imbalances, or severe illnesses.  [from MedlinePlus]

MedGen UID:
5689
Concept ID:
C0020456
Finding
4.

Fasting

Abstaining from all food. [from MeSH]

MedGen UID:
5129
Concept ID:
C0015663
Finding
5.

Dawn phenomenon

MedGen UID:
574950
Concept ID:
C0342314
Pathologic Function
6.

Spondylometaepiphyseal dysplasia short limb-hand type

MedGen UID:
338595
Concept ID:
C1849011
Disease or Syndrome
7.

Insulin, Short-Acting

Insulin derivatives and preparations that are designed to induce a rapid HYPOGLYCEMIC EFFECT. [from MeSH]

MedGen UID:
452462
Concept ID:
C0356365
Pharmacologic Substance
8.

Insulin, Long-Acting

Insulin formulations that contain substances that retard absorption thus extending the time period of action. [from MeSH]

MedGen UID:
137116
Concept ID:
C0304870
Pharmacologic Substance
9.

Humalog

MedGen UID:
101953
Concept ID:
C0528249
Pharmacologic Substance
10.

Insulin Lispro

Insulin that has been modified so that the B-chain contains a LYSINE at position 28 instead of a PROLINE and a PROLINE at position 29 instead of a LYSINE. [from MeSH]

MedGen UID:
80428
Concept ID:
C0293359
Pharmacologic Substance
11.

Insulin, Prompt Zinc

MedGen UID:
7101
Concept ID:
C0021663
Pharmacologic Substance

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