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Results: 1 to 20 of 46

1.

Head & Shoulders brand of selenium disulfide

MedGen UID:
280641
Concept ID:
C1531398
Pharmacologic Substance
2.

Malignant neoplastic disease

A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified. [from NCI]

MedGen UID:
14297
Concept ID:
C0006826
Neoplastic Process
3.

Neoplasm of head and neck

A neoplasm of the head and neck region with origin in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and larynx. [from HPO]

MedGen UID:
501086
Concept ID:
CN168964
Finding
4.

dasatinib

An orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases. Apparently because of its less stringent binding affinity for the BCR-ABL kinase, dasatinib has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations. SRC-family protein-tyrosine kinases interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways; tumorigenic forms can occur through altered regulation or expression of the endogenous protein and by way of virally-encoded kinase genes. [from NCI]

MedGen UID:
305964
Concept ID:
C1455147
Pharmacologic Substance
5.

Phosphorylation

A process in which a phosphate group is added to a molecule, such as a sugar or a protein. [from NCI]

MedGen UID:
10742
Concept ID:
C0031715
Molecular Function
6.

Yes

MedGen UID:
720794
Concept ID:
C1298907
Finding
7.

Detected

MedGen UID:
617726
Concept ID:
C0442726
Finding
8.

Dasatinib

MedGen UID:
449995
Concept ID:
CN077520
Pharmacologic Substance
9.

Cell Invasion

The movement of one cell type into an area normally occupied by a different cell type. [from NCI]

MedGen UID:
397081
Concept ID:
C2699153
Pathologic Function
10.

Squamous cell carcinoma of the head and neck

Cancer of the head and neck that begins in squamous cells (thin, flat cells that form the surface of the skin, eyes, various internal organs, and the lining of hollow organs and ducts of some glands). Squamous cell carcinoma of the head and neck includes cancers of the nasal cavity, sinuses, lips, mouth, salivary glands, throat, and larynx (voice box). Most head and neck cancers are squamous cell carcinomas. [from NCI]

MedGen UID:
257911
Concept ID:
C1168401
Neoplastic Process
11.

Growth and reproduction of new similar forms, e.g. cells, buds, or offspring. [from NCI]

MedGen UID:
137720
Concept ID:
C0334094
12.

Aggressive behavior

MedGen UID:
98408
Concept ID:
C0424323
Finding
13.

Tumor progression

A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a neoplasm. [from NCI]

MedGen UID:
61255
Concept ID:
C0178874
Neoplastic Process
14.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
15.

Aggressive behavior

Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism. [from MeSH]

MedGen UID:
1375
Concept ID:
C0001807
Mental or Behavioral Dysfunction
16.

Epithelial neoplasm

neoplasm of epithelial origin, ranging from benign (adenoma and papilloma) to malignant (carcinoma). [from CRISP]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
17.

Biochemical Processes

Chemical reactions or functions, enzymatic activities, and metabolic pathways of living things. [from MeSH]

MedGen UID:
267723
Concept ID:
C1511130
Molecular Function
18.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
19.

Stages or progression of physical or mental disorders. Compare PROGNOSIS. [from PSY]

MedGen UID:
116631
Concept ID:
C0242656
20.

MedGen UID:
108834
Concept ID:
C0591833

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