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Results: 10

1.

Pain

MedGen UID:
776584
Concept ID:
C2364139
Finding
2.

Fatigue

MedGen UID:
776580
Concept ID:
C2364051
Finding
3.

Hypertension

A finding of increased blood pressure; not necessarily hypertensive disorder [from SNOMED CT]

MedGen UID:
635666
Concept ID:
C0497247
Finding
4.

Abdominal pain

An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen. [from HPO]

MedGen UID:
505060
Concept ID:
CN001834
Finding
5.

Gastrointestinal stroma tumor

MedGen UID:
451979
Concept ID:
CN117614
Finding
6.

Nilotinib response

MedGen UID:
450470
Concept ID:
CN077998
Sign or Symptom
7.

Imatinib response

MedGen UID:
450460
Concept ID:
CN077988
Sign or Symptom
8.

Paraganglioma and gastric stromal sarcoma

A rare, inherited disorder marked by tumors of the gastrointestinal tract and tumors that form in embryonic nervous tissue in the head, neck, and torso. [from NCI]

MedGen UID:
376098
Concept ID:
C1847319
Neoplastic Process
9.

Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors are mesenchymal tumors found in the gastrointestinal tract that originate from the interstitial cells of Cajal, the pacemaker cells that regulate peristalsis in the digestive tract. Approximately 70% of GISTs develop in the stomach, 20% in the small intestine, and less than 10% in the esophagus, colon, and rectum. GISTs are typically more cellular than other gastrointestinal sarcomas. They occur predominantly in patients who are 40 to 70 years old but in rare cases may occur in younger persons (Miettinen et al., 1999, 1999). GISTs can also be seen in neurofibromatosis-1 (NF1; 162200) due to mutations in the NF1 gene, and are thus distinct from the GISTs described here. Sandberg and Bridge (2002) reviewed the cytogenetics and molecular genetics of gastrointestinal stromal tumors. Coffey et al. (2007) reviewed the clinical features, pathogenesis, and molecular treatments of Menetrier disease (137280) and GIST, both of which are hyperproliferative disorders of the stomach caused by dysregulated receptor tyrosine kinases. [from OMIM]

MedGen UID:
116049
Concept ID:
C0238198
Neoplastic Process
10.

Neoplasm

A general term for autonomous tissue growth in which the malignancy status has not been established and for which the transformed cell type has not been specifically identified. [from NCI]

MedGen UID:
10294
Concept ID:
C0027651
Neoplastic Process

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