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1.

Infection

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. [from MeSH]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
2.

Infection

Unknown contamination with disease-producing germs. [from HHCC]

MedGen UID:
43874
Concept ID:
C0021311
Disease or Syndrome
3.

Communicable Diseases

Infectious diseases kill more people worldwide than any other single cause. Infectious diseases are caused by germs. Germs are tiny living things that are found everywhere - in air, soil and water. You can get infected by touching, eating, drinking or breathing something that contains a germ. Germs can also spread through animal and insect bites, kissing and sexual contact. Vaccines, proper hand washing and medicines can help prevent infections. . There are four main kinds of germs: : - Bacteria - one-celled germs that multiply quickly and may release chemicals which can make you sick. - Viruses - capsules that contain genetic material, and use your own cells to multiply. - Fungi - primitive plants, like mushrooms or mildew . - Protozoa - one-celled animals that use other living things for food and a place to live. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
1057
Concept ID:
C0009450
Disease or Syndrome
4.

Immune status

Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances. [from MeSH]

MedGen UID:
9426
Concept ID:
C0020964
Finding
5.

Herpes simplex

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted disease (STD). It affects the genitals, buttocks or anal area. Other herpes infections can affect the eyes, skin, or other parts of the body. The virus can be dangerous in newborn babies or in people with weak immune systems. There are two types of HSV:: -HSV type 1 most commonly causes cold sores. It can also cause genital herpes. -HSV type 2 is the usual cause of genital herpes, but it also can infect the mouth. HSV spreads direct contact. Some people have no symptoms. Others get sores near the area where the virus has entered the body. They turn into blisters, become itchy and painful, and then heal. Most people have outbreaks several times a year. Over time, you get them less often. Medicines to help your body fight the virus can help lessen symptoms and decrease outbreaks.  [from MedlinePlus]

MedGen UID:
9234
Concept ID:
C0019348
Disease or Syndrome
6.

Interferon-alpha

a protein produced by the body in response to an infection [from CHV]

MedGen UID:
7985
Concept ID:
C0002199
Pharmacologic Substance
7.

Infections

MedGen UID:
833099
Concept ID:
CN228891
Finding
8.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
9.

Plaque

In medicine, a small, abnormal patch of tissue on a body part or an organ. Plaques may also be a build-up of substances from a fluid, such as cholesterol in the blood vessels. [from NCI]

MedGen UID:
452424
Concept ID:
C0332461
Finding
10.

Spondylometaepiphyseal dysplasia short limb-hand type

MedGen UID:
338595
Concept ID:
C1849011
Disease or Syndrome
11.

Nuclear Translocation

Nuclear Translocation is a subcellular process in which activated cytoplasmic proteins are transported into the cell nucleus as part of a signal transduction pathway to modify cell function (typically gene expression) in response to a signaling event or condition. [from NCI]

MedGen UID:
273609
Concept ID:
C1518440
Molecular Function
12.

human leukocyte interferon

A biological response modifier (a substance that can improve the body's natural response to infection and disease). Interferons interfere with the division of cancer cells and can slow tumor growth. There are several types of interferons, including interferon-alpha, -beta, and -gamma. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases. [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Pharmacologic Substance
13.

Acute

Symptoms or signs that begin and worsen quickly; not chronic. [from NCI]

MedGen UID:
61381
Concept ID:
C0205178
14.

Dental plaque

film that attaches to teeth, often causing dental caries and gingivitis; composed of mucins, secreted from salivary glands, and microorganisms. [from CRISP]

MedGen UID:
8301
Concept ID:
C0011389
Disease or Syndrome
15.

Herpes NOS

Any inflammatory skin disease caused by a herpesvirus and characterized by the formation of small vesicles in clusters. [from NCI]

MedGen UID:
6821
Concept ID:
C0019340
Disease or Syndrome
16.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Pharmacologic Substance
17.

Murine

MedGen UID:
108834
Concept ID:
C0591833
Pharmacologic Substance
18.

Viral Load result

The quantity of measurable virus in a body fluid. Change in viral load, measured in plasma, is sometimes used as a SURROGATE MARKER in disease progression. [from MeSH]

MedGen UID:
84035
Concept ID:
C0376705
Finding
19.

Viral disease

Viruses are capsules with genetic material inside. They are very tiny, much smaller than bacteria. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox and hemorrhagic fevers. . Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This eventually kills the cells, which can make you sick. Viral infections are hard to treat because viruses live inside your body's cells. They are protected from medicines, which usually move through your bloodstream. Antibiotics do not work for viral infections. There are a few antiviral medicines available. Vaccines can help prevent you from getting many viral diseases. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
20.

DNA Virus Infections

MedGen UID:
41636
Concept ID:
C0012922
Disease or Syndrome

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