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reflux

MedGen UID:
66675
Concept ID:
C0232483
Pathologic Function
Synonym: Reflux

Definition

An abnormal backward flow of a body fluid. [from NCI]

Professional guidelines

PubMed

Yadlapati R, Gyawali CP, Pandolfino JE; CGIT GERD Consensus Conference Participants
Clin Gastroenterol Hepatol 2022 May;20(5):984-994.e1. Epub 2022 Feb 2 doi: 10.1016/j.cgh.2022.01.025. PMID: 35123084Free PMC Article
Katz PO, Dunbar KB, Schnoll-Sussman FH, Greer KB, Yadlapati R, Spechler SJ
Am J Gastroenterol 2022 Jan 1;117(1):27-56. doi: 10.14309/ajg.0000000000001538. PMID: 34807007Free PMC Article
Chen J, Brady P
Gastroenterol Nurs 2019 Jan/Feb;42(1):20-28. doi: 10.1097/SGA.0000000000000359. PMID: 30688703

Recent clinical studies

Etiology

Patel J, Wong N, Mehta K, Patel A
Prim Care 2023 Sep;50(3):339-350. Epub 2023 Apr 20 doi: 10.1016/j.pop.2023.03.002. PMID: 37516506
Mattoo TK, Mohammad D
Pediatr Clin North Am 2022 Dec;69(6):1115-1129. Epub 2022 Oct 29 doi: 10.1016/j.pcl.2022.07.007. PMID: 36880925
Cheng J, Ouwehand AC
Nutrients 2020 Jan 2;12(1) doi: 10.3390/nu12010132. PMID: 31906573Free PMC Article
Mungan Z, Pınarbaşı Şimşek B
Turk J Gastroenterol 2017 Dec;28(Suppl 1):S38-S43. doi: 10.5152/tjg.2017.11. PMID: 29199166
Dağlı Ü, Kalkan İH
Turk J Gastroenterol 2017 Dec;28(Suppl 1):S33-S37. doi: 10.5152/tjg.2017.10. PMID: 29199165

Diagnosis

Patel J, Wong N, Mehta K, Patel A
Prim Care 2023 Sep;50(3):339-350. Epub 2023 Apr 20 doi: 10.1016/j.pop.2023.03.002. PMID: 37516506
Krause AJ, Walsh EH, Weissbrod PA, Taft TH, Yadlapati R
Ann N Y Acad Sci 2022 Apr;1510(1):5-17. Epub 2021 Dec 17 doi: 10.1111/nyas.14728. PMID: 34921412Free PMC Article
Fass R, Boeckxstaens GE, El-Serag H, Rosen R, Sifrim D, Vaezi MF
Nat Rev Dis Primers 2021 Jul 29;7(1):55. doi: 10.1038/s41572-021-00287-w. PMID: 34326345
Young A, Kumar MA, Thota PN
Cleve Clin J Med 2020 Apr;87(4):223-230. doi: 10.3949/ccjm.87a.19114. PMID: 32238378
Chabra S, Peeples ES
Pediatr Ann 2020 Feb 1;49(2):e77-e81. doi: 10.3928/19382359-20200121-02. PMID: 32045486

Therapy

Thurber KM, Otto AO, Stricker SL
Am J Health Syst Pharm 2023 Apr 8;80(8):487-494. doi: 10.1093/ajhp/zxad009. PMID: 36629265
Rebelo F, Mansur IR, Miglioli TC, Meio MDB, Junior SCG
PLoS One 2022;17(7):e0271993. Epub 2022 Jul 22 doi: 10.1371/journal.pone.0271993. PMID: 35867728Free PMC Article
Qiu K, Wang J, Chen B, Wang H, Ma C
Ann Palliat Med 2020 Mar;9(2):405-413. Epub 2020 Mar 17 doi: 10.21037/apm.2020.02.35. PMID: 32233626
Graham DY, Tansel A
Clin Gastroenterol Hepatol 2018 Jun;16(6):800-808.e7. Epub 2017 Sep 28 doi: 10.1016/j.cgh.2017.09.033. PMID: 28964908Free PMC Article
Brady M, Kinn S, Stuart P
Cochrane Database Syst Rev 2003;(4):CD004423. doi: 10.1002/14651858.CD004423. PMID: 14584013

Prognosis

Holmberg D, Santoni G, von Euler-Chelpin M, Färkkilä M, Kauppila JH, Maret-Ouda J, Ness-Jensen E, Lagergren J
BMJ 2023 Sep 13;382:e076017. doi: 10.1136/bmj-2023-076017. PMID: 37704252Free PMC Article
Zhang D, Liu S, Li Z, Wang R
Ann Med 2022 Dec;54(1):1372-1384. doi: 10.1080/07853890.2022.2074535. PMID: 35579516Free PMC Article
Zheng Z, Shang Y, Wang N, Liu X, Xin C, Yan X, Zhai Y, Yin J, Zhang J, Zhang Z
Int J Biol Sci 2021;17(15):4154-4164. Epub 2021 Oct 3 doi: 10.7150/ijbs.65066. PMID: 34803489Free PMC Article
DiSiena M, Perelman A, Birk J, Rezaizadeh H
South Med J 2021 Mar;114(3):161-168. doi: 10.14423/SMJ.0000000000001226. PMID: 33655310
Hodges SJ, Werle D, McLorie G, Atala A
ScientificWorldJournal 2010 Apr 13;10:603-12. doi: 10.1100/tsw.2010.54. PMID: 20419273Free PMC Article

Clinical prediction guides

Khoma O, Burton L, Falk MG, Van der Wall H, Falk GL
Esophagus 2020 Jul;17(3):355-362. Epub 2020 Feb 21 doi: 10.1007/s10388-020-00726-9. PMID: 32086701
Stachler RJ, Dworkin-Valenti JP
Curr Opin Otolaryngol Head Neck Surg 2017 Jun;25(3):242-246. doi: 10.1097/MOO.0000000000000354. PMID: 28266945
Malgor RD, Labropoulos N
Phlebology 2013 Mar;28 Suppl 1:51-4. doi: 10.1177/0268355513476637. PMID: 23482535
Williams G, Fletcher JT, Alexander SI, Craig JC
J Am Soc Nephrol 2008 May;19(5):847-62. Epub 2008 Mar 5 doi: 10.1681/ASN.2007020245. PMID: 18322164
Lundell LR, Dent J, Bennett JR, Blum AL, Armstrong D, Galmiche JP, Johnson F, Hongo M, Richter JE, Spechler SJ, Tytgat GN, Wallin L
Gut 1999 Aug;45(2):172-80. doi: 10.1136/gut.45.2.172. PMID: 10403727Free PMC Article

Recent systematic reviews

Zdrhova L, Bitnar P, Balihar K, Kolar P, Madle K, Martinek M, Pandolfino JE, Martinek J
Dysphagia 2023 Apr;38(2):609-621. Epub 2022 Jul 16 doi: 10.1007/s00455-022-10494-6. PMID: 35842548Free PMC Article
Cheng J, Ouwehand AC
Nutrients 2020 Jan 2;12(1) doi: 10.3390/nu12010132. PMID: 31906573Free PMC Article
Eusebi LH, Ratnakumaran R, Yuan Y, Solaymani-Dodaran M, Bazzoli F, Ford AC
Gut 2018 Mar;67(3):430-440. Epub 2017 Feb 23 doi: 10.1136/gutjnl-2016-313589. PMID: 28232473
Mungan Z, Pınarbaşı Şimşek B
Turk J Gastroenterol 2017 Dec;28(Suppl 1):S38-S43. doi: 10.5152/tjg.2017.11. PMID: 29199166
Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R; Global Consensus Group
Am J Gastroenterol 2006 Aug;101(8):1900-20; quiz 1943. doi: 10.1111/j.1572-0241.2006.00630.x. PMID: 16928254

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