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Results: 1 to 20 of 25

1.

Cisplatin

An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. [from NCI]

MedGen UID:
40318
Concept ID:
C0008838
Pharmacologic Substance
2.

Carboplatin

A drug that is used to treat advanced ovarian cancer that has never been treated or symptoms of ovarian cancer that has come back after treatment with other anticancer drugs. It is also used with other drugs to treat advanced, metastatic, or recurrent non-small cell lung cancer and is being studied in the treatment of other types of cancer. Paraplatin is a form of the anticancer drug cisplatin and causes fewer side effects in patients. It attaches to DNA in cells and may kill cancer cells. It is a type of platinum compound. [from NCI]

MedGen UID:
38172
Concept ID:
C0079083
Pharmacologic Substance
3.

Malignant Neoplasm

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body. . Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, biologic therapy, or stem cell transplantation. . NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
14297
Concept ID:
C0006826
Neoplastic Process
4.

Cytarabine

A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) [from MeSH]

MedGen UID:
1210
Concept ID:
C0010711
Pharmacologic Substance
5.

Indicated

MedGen UID:
731837
Concept ID:
C1444656
Finding
6.

Error occurred: cannot get document summary

ID:
272128

7.

cytotoxicity

The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to kill rapidly growing tumor cells. In the killing of tumor cells, other cells that are rapidly growing e.g hair, mucous membranes are also killed. [from NCI]

MedGen UID:
108579
Concept ID:
C0596402
Cell or Molecular Dysfunction
8.

Tumorigenesis

A pathologic process that involves the transformation of normal cells to a neoplastic state and resulting in polyclonal or monoclonal neoplastic cell proliferation. [from NCI]

MedGen UID:
3302
Concept ID:
C0007621
Neoplastic Process
9.

Nealorin

MedGen UID:
308906
Concept ID:
C1516258
Pharmacologic Substance
10.

Neocarbo

MedGen UID:
289846
Concept ID:
C1564517
Pharmacologic Substance
11.

Carbotec

MedGen UID:
275675
Concept ID:
C1516255
Pharmacologic Substance
12.

Carbosin

MedGen UID:
275673
Concept ID:
C1516253
Pharmacologic Substance
13.

Ercar

MedGen UID:
273867
Concept ID:
C1516257
Pharmacologic Substance
14.

Blastocarb

MedGen UID:
273866
Concept ID:
C1516252
Pharmacologic Substance
15.

Ribocarbo

MedGen UID:
273087
Concept ID:
C1516262
Pharmacologic Substance
16.

Platinwas

MedGen UID:
273086
Concept ID:
C1516261
Pharmacologic Substance
17.

NSC-241240

MedGen UID:
196416
Concept ID:
C0729067
Pharmacologic Substance
18.

Platinol

MedGen UID:
195927
Concept ID:
C0699666
Pharmacologic Substance
19.

NSC-119875

MedGen UID:
181696
Concept ID:
C0936226
Pharmacologic Substance
20.

JM-8

MedGen UID:
152629
Concept ID:
C0729066
Pharmacologic Substance

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