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Results: 1 to 20 of 26

1.

Inflammation

A microscopic finding indicating the presence of acute, subacute or chronic inflammation in a tissue sample. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
2.

Enlargement

MedGen UID:
751217
Concept ID:
C2711450
Anatomical Abnormality
3.

Chronic obstructive pulmonary disease

MedGen UID:
505916
Concept ID:
CN005670
Finding
4.

Chronic

A disease or condition that persists or progresses over a long period of time. [from NCI_NCI-GLOSS]

MedGen UID:
104657
Concept ID:
C0205191
5.

Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality. COPD is defined by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. Airflow obstruction is typically determined by reductions in quantitative spirometric indices, including forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) (Silverman et al., 2002; Celedon et al., 2004). [from OMIM]

MedGen UID:
9818
Concept ID:
C0024117
Disease or Syndrome
6.

Pulmonary emphysema

Emphysema is a type of chronic obstructive pulmonary disease (COPD) involving damage to the air sacs (alveoli) in the lungs. As a result, your body does not get the oxygen it needs. Emphysema makes it hard to catch your breath. You may also have a chronic cough and have trouble breathing during exercise. The most common cause is cigarette smoking. If you smoke, quitting can help prevent you from getting the disease. If you already have emphysema, not smoking might keep it from getting worse. Treatment is based on whether your symptoms are mild, moderate or severe. Treatments include inhalers, oxygen, medications and sometimes surgery to relieve symptoms and prevent complications. .  [from MedlinePlus]

MedGen UID:
18764
Concept ID:
C0034067
Disease or Syndrome
7.

Emphysema

A pathological accumulation of air in tissues or organs. [from MeSH]

MedGen UID:
4925
Concept ID:
C0013990
Pathologic Function
8.

Disease

Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. [from NCI]

MedGen UID:
4347
Concept ID:
C0012634
Disease or Syndrome
9.

disease

An alteration of health status resulting from a physiopathological mechanism, and having a homogeneous clinical presentation and evolution and homogeneous therapeutic possibilities. Excludes developmental anomalies. [from ORDO]

MedGen UID:
798428
Concept ID:
CN204926
Disease or Syndrome
10.

Emphysema

MedGen UID:
425087
Concept ID:
CN001898
Finding
11.

Disease Response

The pathologic and/or clinical changes that result from treatment. The changes may include eradication of detectable disease, stabilization of disease, or disease progression. [from NCI]

MedGen UID:
309976
Concept ID:
C1704632
Finding
12.

Inflammatory Response

A part of innate immunity, the Inflammatory Response occurs when injured tissues induce release of vasodilatory, opsonizing, and chemotactic mediators that attract macrophages and leukocytes to phagocytize and destroy foreign substances; dilate local blood vessels increasing local blood flow; increase capillary permeability; produce edematous swelling; and induce pain. Plasma- and cell-derived inflammatory mediators include Prostaglandins, Leukotrines, Cytokines, Lymphokines, Monokines, PAF, Histamine, Bradykinin, Complement, and Interferons. [from NCI]

MedGen UID:
218869
Concept ID:
C1155266
Pathologic Function
13.

Protein-Protein Interaction

Temporary, non-covalent binding between protein molecules. Protein-protein interactions occur as a result of intermolecular physical forces and spatial complementation between domains or motifs. This interaction can be either homotypic or heterotypic and effect protein structure, conformation, and function. [from NCI]

MedGen UID:
209050
Concept ID:
C0872079
Molecular Function
14.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
15.

Antioxidants

Antioxidants are substances that may protect your cells against the effects of free radicals. Free radicals are molecules produced when your body breaks down food, or by environmental exposures like tobacco smoke and radiation. Free radicals can damage cells, and may play a role in heart disease, cancer and other diseases. . Antioxidant substances include : - Beta-carotene . - Lutein . - Lycopene. - Selenium. - Vitamin A. - Vitamin C. - Vitamin E. Antioxidants are found in many foods. These include fruits and vegetables, nuts, grains, and some meats, poultry and fish. .  [from MedlinePlus]

MedGen UID:
1608
Concept ID:
C0003402
Pharmacologic Substance
16.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
17.

Lung Diseases, Obstructive

Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent. [from MeSH]

MedGen UID:
154671
Concept ID:
C0600260
Disease or Syndrome
18.

Genetic predisposition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

MedGen UID:
137259
Concept ID:
C0314657
19.

Murine

MedGen UID:
108834
Concept ID:
C0591833
Pharmacologic Substance
20.

Pathological Conditions, Signs and Symptoms

Abnormal anatomical or physiological conditions and objective or subjective manifestations of disease, not classified as disease or syndrome. [from MeSH]

MedGen UID:
21047
Concept ID:
C0039058
Sign or Symptom

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