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Congenital rubella syndrome

MedGen UID:
19841
Concept ID:
C0035921
Congenital Abnormality; Disease or Syndrome
Synonyms: Congenital Rubella Syndrome; Congenital Rubella Syndromes; Rubella Syndrome, Congenital; Rubella Syndromes, Congenital; Syndrome, Congenital Rubella; Syndromes, Congenital Rubella
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Congenital rubella syndrome (1857005); Gestational rubella syndrome (1857005); Gregg's syndrome (1857005); Congenital rubella (1857005)
 
Orphanet: ORPHA290

Definition

Transplacental infection of the fetus with rubella usually in the first trimester of pregnancy, as a consequence of maternal infection, resulting in various developmental abnormalities in the newborn infant. They include cardiac and ocular lesions, deafness, microcephaly, mental retardation, and generalized growth retardation. (From Dorland, 27th ed) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGCongenital rubella syndrome
Follow this link to review classifications for Congenital rubella syndrome in Orphanet.

Recent clinical studies

Etiology

Mao B, Chheng K, Wannemuehler K, Vynnycky E, Buth S, Soeung SC, Reef S, Weldon W, Quick L, Gregory CJ
Epidemiol Infect 2015 Jul;143(9):1858-67. Epub 2014 Nov 6 doi: 10.1017/S0950268814002817. [Epub ahead of print] PMID: 25373419
Hyde TB, Sato HK, Hao L, Flannery B, Zheng Q, Wannemuehler K, Ciccone FH, de Sousa Marques H, Weckx LY, Sáfadi MA, de Oliveira Moraes E, Pinhata MM, Olbrich Neto J, Bevilacqua MC, Tabith Junior A, Monteiro TA, Figueiredo CA, Andrus JK, Reef SE, Toscano CM, Castillo-Solorzano C, Icenogle JP; CRS Biomarker Study Group
J Infect Dis 2015 Jul 1;212(1):57-66. Epub 2014 Oct 31 doi: 10.1093/infdis/jiu604. [Epub ahead of print] PMID: 25362195
Shah SK, Praveen MR, Vasavada AR, Vasavada VA, Carelli R, Trivedi RH, Rasoebala V
J Cataract Refract Surg 2014 Dec;40(12):2091-8. Epub 2014 Nov 24 doi: 10.1016/j.jcrs.2014.04.028. [Epub ahead of print] PMID: 25465688
Van Bang N, Van Anh NT, Van VT, Thai TT, Van Thuong N, Khandaker G, Elliott E
Vaccine 2014 Dec 12;32(52):7065-9. Epub 2014 Nov 11 doi: 10.1016/j.vaccine.2014.10.087. [Epub ahead of print] PMID: 25444828
Pitts SI, Wallace GS, Montana B, Handschur EF, Meislich D, Sampson AC, Canuso S, Horner J, Barskey AE, Abernathy ES, Icenogle JP
Emerg Infect Dis 2014 Feb;20(2):307-9. doi: 10.3201/eid2002.131233. PMID: 24447409Free PMC Article

Diagnosis

Hyde TB, Sato HK, Hao L, Flannery B, Zheng Q, Wannemuehler K, Ciccone FH, de Sousa Marques H, Weckx LY, Sáfadi MA, de Oliveira Moraes E, Pinhata MM, Olbrich Neto J, Bevilacqua MC, Tabith Junior A, Monteiro TA, Figueiredo CA, Andrus JK, Reef SE, Toscano CM, Castillo-Solorzano C, Icenogle JP; CRS Biomarker Study Group
J Infect Dis 2015 Jul 1;212(1):57-66. Epub 2014 Oct 31 doi: 10.1093/infdis/jiu604. [Epub ahead of print] PMID: 25362195
Shah SK, Praveen MR, Vasavada AR, Vasavada VA, Carelli R, Trivedi RH, Rasoebala V
J Cataract Refract Surg 2014 Dec;40(12):2091-8. Epub 2014 Nov 24 doi: 10.1016/j.jcrs.2014.04.028. [Epub ahead of print] PMID: 25465688
Van Bang N, Van Anh NT, Van VT, Thai TT, Van Thuong N, Khandaker G, Elliott E
Vaccine 2014 Dec 12;32(52):7065-9. Epub 2014 Nov 11 doi: 10.1016/j.vaccine.2014.10.087. [Epub ahead of print] PMID: 25444828
Toizumi M, Motomura H, Vo HM, Takahashi K, Pham E, Nguyen HA, Le TH, Hashizume M, Ariyoshi K, Dang DA, Moriuchi H, Yoshida LM
Pediatrics 2014 Aug;134(2):e519-26. Epub 2014 Jul 7 doi: 10.1542/peds.2013-4184. [Epub ahead of print] PMID: 25002666
Pitts SI, Wallace GS, Montana B, Handschur EF, Meislich D, Sampson AC, Canuso S, Horner J, Barskey AE, Abernathy ES, Icenogle JP
Emerg Infect Dis 2014 Feb;20(2):307-9. doi: 10.3201/eid2002.131233. PMID: 24447409Free PMC Article

Therapy

Shah SK, Praveen MR, Vasavada AR, Vasavada VA, Carelli R, Trivedi RH, Rasoebala V
J Cataract Refract Surg 2014 Dec;40(12):2091-8. Epub 2014 Nov 24 doi: 10.1016/j.jcrs.2014.04.028. [Epub ahead of print] PMID: 25465688
Takakura A, Haug SJ, Radhakrishnan S, Fu AD, Jumper JM, MacDonald HR, Johnson RN, Lujan BJ, Cunningham ET Jr
Retin Cases Brief Rep 2014 Spring;8(2):153-6. doi: 10.1097/ICB.0000000000000029. PMID: 25372335
Pitts SI, Wallace GS, Montana B, Handschur EF, Meislich D, Sampson AC, Canuso S, Horner J, Barskey AE, Abernathy ES, Icenogle JP
Emerg Infect Dis 2014 Feb;20(2):307-9. doi: 10.3201/eid2002.131233. PMID: 24447409Free PMC Article
McLean HQ, Fiebelkorn AP, Temte JL, Wallace GS; Centers for Disease Control and Prevention
MMWR Recomm Rep 2013 Jun 14;62(RR-04):1-34. PMID: 23760231
Gao Z, Wood JG, Burgess MA, Menzies RI, McIntyre PB, MacIntyre CR
Vaccine 2013 Jan 11;31(4):691-7. Epub 2012 Nov 26 doi: 10.1016/j.vaccine.2012.11.043. [Epub ahead of print] PMID: 23196206

Prognosis

Mao B, Chheng K, Wannemuehler K, Vynnycky E, Buth S, Soeung SC, Reef S, Weldon W, Quick L, Gregory CJ
Epidemiol Infect 2015 Jul;143(9):1858-67. Epub 2014 Nov 6 doi: 10.1017/S0950268814002817. [Epub ahead of print] PMID: 25373419
Shah SK, Praveen MR, Vasavada AR, Vasavada VA, Carelli R, Trivedi RH, Rasoebala V
J Cataract Refract Surg 2014 Dec;40(12):2091-8. Epub 2014 Nov 24 doi: 10.1016/j.jcrs.2014.04.028. [Epub ahead of print] PMID: 25465688
Toizumi M, Motomura H, Vo HM, Takahashi K, Pham E, Nguyen HA, Le TH, Hashizume M, Ariyoshi K, Dang DA, Moriuchi H, Yoshida LM
Pediatrics 2014 Aug;134(2):e519-26. Epub 2014 Jul 7 doi: 10.1542/peds.2013-4184. [Epub ahead of print] PMID: 25002666
Centers for Disease Control and Prevention (CDC)
MMWR Morb Mortal Wkly Rep 2013 Dec 6;62(48):983-6. PMID: 24304830
Gao Z, Wood JG, Burgess MA, Menzies RI, McIntyre PB, MacIntyre CR
Vaccine 2013 Jan 11;31(4):691-7. Epub 2012 Nov 26 doi: 10.1016/j.vaccine.2012.11.043. [Epub ahead of print] PMID: 23196206

Clinical prediction guides

Mao B, Chheng K, Wannemuehler K, Vynnycky E, Buth S, Soeung SC, Reef S, Weldon W, Quick L, Gregory CJ
Epidemiol Infect 2015 Jul;143(9):1858-67. Epub 2014 Nov 6 doi: 10.1017/S0950268814002817. [Epub ahead of print] PMID: 25373419
Shah SK, Praveen MR, Vasavada AR, Vasavada VA, Carelli R, Trivedi RH, Rasoebala V
J Cataract Refract Surg 2014 Dec;40(12):2091-8. Epub 2014 Nov 24 doi: 10.1016/j.jcrs.2014.04.028. [Epub ahead of print] PMID: 25465688
Gao Z, Wood JG, Burgess MA, Menzies RI, McIntyre PB, MacIntyre CR
Vaccine 2013 Jan 11;31(4):691-7. Epub 2012 Nov 26 doi: 10.1016/j.vaccine.2012.11.043. [Epub ahead of print] PMID: 23196206
Castillo-Solórzano C, Reef SE, Morice A, Vascones N, Chevez AE, Castalia-Soares R, Torres C, Vizzotti C, Ruiz Matus C
J Infect Dis 2011 Sep 1;204 Suppl 2:S713-7. doi: 10.1093/infdis/jir489. PMID: 21954271
Zimmerman LA, Muscat M, Jankovic D, Goel A, Bang H, Khetsuriani N, Martin R
J Infect Dis 2011 Jul;204 Suppl 1:S381-8. doi: 10.1093/infdis/jir104. PMID: 21666188

Recent systematic reviews

Babigumira JB, Morgan I, Levin A
BMC Public Health 2013 Apr 29;13:406. doi: 10.1186/1471-2458-13-406. [Epub ahead of print] PMID: 23627715Free PMC Article
Mongua-Rodriguez N, Díaz-Ortega JL, García-García L, Piña-Pozas M, Ferreira-Guerrero E, Delgado-Sánchez G, Ferreyra-Reyes L, Cruz-Hervert LP, Baez-Saldaña R, Campos-Montero R
Vaccine 2013 Apr 19;31(17):2145-51. Epub 2013 Mar 5 doi: 10.1016/j.vaccine.2013.02.047. [Epub ahead of print] PMID: 23470237
Dewan P, Gupta P
Indian Pediatr 2012 May;49(5):377-99. PMID: 22700664
Al-Awaidy S, Griffiths UK, Nwar HM, Bawikar S, Al-Aisiri MS, Khandekar R, Mohammad AJ, Robertson SE
Vaccine 2006 Sep 29;24(40-41):6437-45. Epub 2006 Jun 13 doi: 10.1016/j.vaccine.2006.05.089. [Epub ahead of print] PMID: 16814433
Watson JC, Hadler SC, Dykewicz CA, Reef S, Phillips L
MMWR Recomm Rep 1998 May 22;47(RR-8):1-57. PMID: 9639369

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