Display Settings:

Format
Items per page

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 12

1.

adefovir dipivoxil

An acyclic nucleotide adenine analogue with potent antiviral activity. Adefovir is activated in vivo to a diphosphate metabolite which is incorporated into viral DNA, leading to viral RNA-dependent DNA polymerase inhibition, DNA chain termination and impairment of viral replication. This agent inhibits the reverse transcriptases of hepatitis B, herpes and HIV viruses, induces natural killer cell activity, and stimulates endogenous interferon production. Viral resistance to adefovir develops at a slower rate compared to other antivirals. (NCI04) [from NCI]

MedGen UID:
154142
Concept ID:
C0540694
Pharmacologic Substance
2.

adefovir

an adenine analog, antiviral agent; used for treating hepatitis, HIV and African swine fever virus infections. [from CRISP]

MedGen UID:
62180
Concept ID:
C0050175
Pharmacologic Substance
3.

Syndrome

A set of symptoms or conditions that occur together and suggest the presence of a certain disease or an increased chance of developing the disease. [from NCI]

MedGen UID:
11688
Concept ID:
C0039082
Disease or Syndrome
4.

Type B viral hepatitis

A viral infection caused by the hepatitis B virus. [from NCI]

MedGen UID:
6807
Concept ID:
C0019163
Disease or Syndrome
5.

Hepatitis

Your liver helps your body digest food, store energy and remove poisons. Hepatitis is a swelling of the liver that makes it stop working well. It can lead to scarring, called cirrhosis, or to cancer. Viruses cause most cases of hepatitis. The type of hepatitis is named for the virus that causes it; for example, hepatitis A, hepatitis B or hepatitis C. Drug or alcohol use can also lead to hepatitis. In other cases, your body mistakenly attacks its own tissues. You can help prevent some viral forms by getting a vaccine. Sometimes hepatitis goes away by itself. If it does not, it can be treated with drugs. Sometimes hepatitis lasts a lifetime. Some people who have hepatitis have no symptoms. Others may have: -Loss of appetite. -Nausea and vomiting. -Diarrhea. -Dark-colored urine and pale bowel movements. -Stomach pain. -Jaundice, yellowing of skin and eyes.  [from MedlinePlus]

MedGen UID:
5515
Concept ID:
C0019158
Disease or Syndrome
6.

Fanconi syndrome

Fanconi renotubular syndrome is a consequence of decreased solute and water reabsorption in the proximal tubule of the kidney. Patients have polydipsia and polyuria with phosphaturia, glycosuria, and aminoaciduria. They may develop hypophosphatemic rickets or osteomalacia, acidosis, and a tendency toward dehydration. Some will eventually develop renal insufficiency. Common laboratory abnormalities include glucosuria with a normal serum glucose, hyperaminoaciduria, hypophosphatemia, progressive renal insufficiency, renal sodium and potassium wasting, acidosis, uricosuria, and low-molecular-weight proteinuria (summary by Lichter-Konecki et al., 2001). Genetic Heterogeneity of Fanconi Renotubular Syndrome Fanconi renotubular syndrome-1 has been mapped to chromosome 15q15.3. See also autosomal recessive FRTS2 (613388), caused by mutation in the SLC34A1 gene (182309) on chromosome 5q35, and autosomal dominant FRTS3 (615605), caused by mutation in the EHHADH gene (607037) on chromosome 3q27. [from OMIM]

MedGen UID:
4653
Concept ID:
C0015624
Disease or Syndrome
7.

Hepatitis

Inflammation of the liver. [from HPO]

MedGen UID:
506667
Concept ID:
CN167841
Finding
8.

Chronic

A disease or condition that persists or progresses over a long period of time. [from NCI]

MedGen UID:
104657
Concept ID:
C0205191
9.

Acquired Fanconi syndrome

Fanconi Syndrome caused by exposure to noxious agents. [from NCI]

MedGen UID:
90966
Concept ID:
C0341702
Disease or Syndrome
10.

Chronic hepatitis

INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. [from MeSH]

MedGen UID:
9223
Concept ID:
C0019189
Disease or Syndrome
11.

Renal tubular dysfunction

MedGen UID:
504351
Concept ID:
CN000120
Finding
12.

Progressive muscle weakness

MedGen UID:
68704
Concept ID:
C0240421
Finding

Display Settings:

Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...