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Rabies

MedGen UID:
48308
Concept ID:
C0034494
Disease or Syndrome
Synonyms: Hydrophobia; Lyssa; Lyssas
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Rabies (14168008); Hydrophobia (14168008); Lyssa (14168008)
 
Orphanet: ORPHA770

Definition

Rabies is a deadly animal disease caused by a virus. It can happen in wild animals, including raccoons, skunks, bats and foxes, or in dogs, cats or farm animals. People get it from the bite of an infected animal. . In people, symptoms of rabies include fever, headache and fatigue, then confusion, hallucinations and paralysis. Once the symptoms begin, the disease is usually fatal. A series of shots can prevent rabies in people exposed to the virus. You need to get them right away. If an animal bites you, wash the wound well; then get medical care. . To help prevent rabies. - Vaccinate your pet. Rabies vaccines are available for dogs, cats and farm animals. - Don't let pets roam. - Don't approach stray animals. Animals with rabies might be aggressive and vicious, or tired and weak. Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRabies
Follow this link to review classifications for Rabies in Orphanet.

Recent clinical studies

Etiology

Hudson EG, Dhand N, Dürr S, Ward MP
PLoS Negl Trop Dis 2016 Apr;10(4):e0004649. Epub 2016 Apr 26 doi: 10.1371/journal.pntd.0004649. PMID: 27115351Free PMC Article
Robardet E, Picard-Meyer E, Dobroštana M, Jaceviciene I, Mähar K, Muižniece Z, Pridotkas G, Masiulis M, Niin E, Olševskis E, Cliquet F
PLoS Negl Trop Dis 2016 Feb;10(2):e0004432. Epub 2016 Feb 5 doi: 10.1371/journal.pntd.0004432. PMID: 26849358Free PMC Article
Tarantola A, Crabol Y, Mahendra BJ, In S, Barennes H, Bourhy H, Peng Y, Ly S, Buchy P
Trop Med Int Health 2016 Apr;21(4):564-7. Epub 2016 Feb 17 doi: 10.1111/tmi.12670. [Epub ahead of print] PMID: 26806229
Mani RS, Anand AM, Madhusudana SN
Trop Med Int Health 2016 Apr;21(4):556-63. Epub 2016 Feb 9 doi: 10.1111/tmi.12669. [Epub ahead of print] PMID: 26799375
Zhang Y, Zhang S, Li W, Hu Y, Zhao J, Liu F, Lin H, Liu Y, Wang L, Xu S, Hu R, Shao H, Li L
Virology 2016 Feb;489:165-72. Epub 2016 Jan 5 doi: 10.1016/j.virol.2015.10.029. [Epub ahead of print] PMID: 26765968

Diagnosis

Hudson EG, Dhand N, Dürr S, Ward MP
PLoS Negl Trop Dis 2016 Apr;10(4):e0004649. Epub 2016 Apr 26 doi: 10.1371/journal.pntd.0004649. PMID: 27115351Free PMC Article
Mtema Z, Changalucha J, Cleaveland S, Elias M, Ferguson HM, Halliday JE, Haydon DT, Jaswant G, Kazwala R, Killeen GF, Lembo T, Lushasi K, Malishee AD, Mancy R, Maziku M, Mbunda EM, Mchau GJ, Murray-Smith R, Rysava K, Said K, Sambo M, Shayo E, Sikana L, Townsend SE, Urassa H, Hampson K
PLoS Med 2016 Apr;13(4):e1002002. Epub 2016 Apr 12 doi: 10.1371/journal.pmed.1002002. PMID: 27070315Free PMC Article
Pratt PD, Henschel K, Turabelidze G, Grim A, Ellison JA, Orciari L, Yager P, Franka R, Wu X, Ma X, Wadhwa A, Smith TG, Petersen B, Shiferaw M
MMWR Morb Mortal Wkly Rep 2016 Mar 18;65(10):253-6. doi: 10.15585/mmwr.mm6510a1. PMID: 26985578
Mani RS, Anand AM, Madhusudana SN
Trop Med Int Health 2016 Apr;21(4):556-63. Epub 2016 Feb 9 doi: 10.1111/tmi.12669. [Epub ahead of print] PMID: 26799375
Ross RS, Wolters B, Hoffmann B, Geue L, Viazov S, Grüner N, Roggendorf M, Müller T
Int J Med Microbiol 2015 Oct;305(7):636-43. Epub 2015 Aug 21 doi: 10.1016/j.ijmm.2015.08.013. [Epub ahead of print] PMID: 26384867

Therapy

Hudson EG, Dhand N, Dürr S, Ward MP
PLoS Negl Trop Dis 2016 Apr;10(4):e0004649. Epub 2016 Apr 26 doi: 10.1371/journal.pntd.0004649. PMID: 27115351Free PMC Article
Mtema Z, Changalucha J, Cleaveland S, Elias M, Ferguson HM, Halliday JE, Haydon DT, Jaswant G, Kazwala R, Killeen GF, Lembo T, Lushasi K, Malishee AD, Mancy R, Maziku M, Mbunda EM, Mchau GJ, Murray-Smith R, Rysava K, Said K, Sambo M, Shayo E, Sikana L, Townsend SE, Urassa H, Hampson K
PLoS Med 2016 Apr;13(4):e1002002. Epub 2016 Apr 12 doi: 10.1371/journal.pmed.1002002. PMID: 27070315Free PMC Article
Robardet E, Picard-Meyer E, Dobroštana M, Jaceviciene I, Mähar K, Muižniece Z, Pridotkas G, Masiulis M, Niin E, Olševskis E, Cliquet F
PLoS Negl Trop Dis 2016 Feb;10(2):e0004432. Epub 2016 Feb 5 doi: 10.1371/journal.pntd.0004432. PMID: 26849358Free PMC Article
Tarantola A, Crabol Y, Mahendra BJ, In S, Barennes H, Bourhy H, Peng Y, Ly S, Buchy P
Trop Med Int Health 2016 Apr;21(4):564-7. Epub 2016 Feb 17 doi: 10.1111/tmi.12670. [Epub ahead of print] PMID: 26806229
Zhang Y, Zhang S, Li W, Hu Y, Zhao J, Liu F, Lin H, Liu Y, Wang L, Xu S, Hu R, Shao H, Li L
Virology 2016 Feb;489:165-72. Epub 2016 Jan 5 doi: 10.1016/j.virol.2015.10.029. [Epub ahead of print] PMID: 26765968

Prognosis

Vodopija R, Racz A, Pahor Đ
Acta Clin Croat 2016 Mar;55(1):151-5. PMID: 27333730
Birhane MG, Miranda ME, Dyer JL, Blanton JD, Recuenco S
PLoS Negl Trop Dis 2016 Mar;10(3):e0004486. Epub 2016 Mar 21 doi: 10.1371/journal.pntd.0004486. PMID: 26999021Free PMC Article
Pratt PD, Henschel K, Turabelidze G, Grim A, Ellison JA, Orciari L, Yager P, Franka R, Wu X, Ma X, Wadhwa A, Smith TG, Petersen B, Shiferaw M
MMWR Morb Mortal Wkly Rep 2016 Mar 18;65(10):253-6. doi: 10.15585/mmwr.mm6510a1. PMID: 26985578
Wallace RM, Reses H, Franka R, Dilius P, Fenelon N, Orciari L, Etheart M, Destine A, Crowdis K, Blanton JD, Francisco C, Ludder F, Del Rio Vilas V, Haim J, Millien M
PLoS Negl Trop Dis 2015 Nov;9(11):e0004245. Epub 2015 Nov 24 doi: 10.1371/journal.pntd.0004245. PMID: 26600437Free PMC Article
M N, V U, Rs M, V G, M A A, M B, S M, A C, P K P, S N M, P S
J Clin Virol 2015 Sep;70:83-8. Epub 2015 Jul 7 doi: 10.1016/j.jcv.2015.07.003. [Epub ahead of print] PMID: 26305826

Clinical prediction guides

Vodopija R, Racz A, Pahor Đ
Acta Clin Croat 2016 Mar;55(1):151-5. PMID: 27333730
Hudson EG, Dhand N, Dürr S, Ward MP
PLoS Negl Trop Dis 2016 Apr;10(4):e0004649. Epub 2016 Apr 26 doi: 10.1371/journal.pntd.0004649. PMID: 27115351Free PMC Article
Birhane MG, Miranda ME, Dyer JL, Blanton JD, Recuenco S
PLoS Negl Trop Dis 2016 Mar;10(3):e0004486. Epub 2016 Mar 21 doi: 10.1371/journal.pntd.0004486. PMID: 26999021Free PMC Article
Tarantola A, Crabol Y, Mahendra BJ, In S, Barennes H, Bourhy H, Peng Y, Ly S, Buchy P
Trop Med Int Health 2016 Apr;21(4):564-7. Epub 2016 Feb 17 doi: 10.1111/tmi.12670. [Epub ahead of print] PMID: 26806229
Nguyen AK, Nguyen HT, Pham TN, Hoang TV, Olowokure B
Public Health 2015 Dec;129(12):1591-6. Epub 2015 Aug 13 doi: 10.1016/j.puhe.2015.07.019. [Epub ahead of print] PMID: 26278473

Recent systematic reviews

Devleesschauwer B, Aryal A, Sharma BK, Ale A, Declercq A, Depraz S, Gaire TN, Gongal G, Karki S, Pandey BD, Pun SB, Duchateau L, Dorny P, Speybroeck N
PLoS Negl Trop Dis 2016 Feb;10(2):e0004461. Epub 2016 Feb 12 doi: 10.1371/journal.pntd.0004461. PMID: 26871689Free PMC Article
Jibat T, Hogeveen H, Mourits MC
PLoS Negl Trop Dis 2015 Feb;9(2):e0003447. Epub 2015 Feb 3 doi: 10.1371/journal.pntd.0003447. PMID: 25646774Free PMC Article
Tsiodras S, Korou LM, Tzani M, Tasioudi KE, Kalachanis K, Mangana-Vougiouka O, Rigakos G, Dougas G, Seimenis AM, Kontos V
Travel Med Infect Dis 2014 Nov-Dec;12(6 Pt A):628-35. Epub 2014 Oct 23 doi: 10.1016/j.tmaid.2014.10.013. [Epub ahead of print] PMID: 25459432
Morters MK, Restif O, Hampson K, Cleaveland S, Wood JL, Conlan AJ
J Anim Ecol 2013 Jan;82(1):6-14. Epub 2012 Sep 24 doi: 10.1111/j.1365-2656.2012.02033.x. [Epub ahead of print] PMID: 23004351Free PMC Article
Davlin SL, Vonville HM
Vaccine 2012 May 21;30(24):3492-502. Epub 2012 Apr 3 doi: 10.1016/j.vaccine.2012.03.069. [Epub ahead of print] PMID: 22480924

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