Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 24

1.

Body mass index

Body mass index (BMI), which reflects the amount of fat, lean mass, and body build, is a heterogeneous trait influenced by both genetic and environmental factors. Several studies have estimated the heritability of body mass index to be 40 to 55% (Bouchard et al., 1998; Rice et al., 1999). [from OMIM]

MedGen UID:
449535
Concept ID:
C2240399
Finding
2.

Genetic predisposition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

MedGen UID:
137259
Concept ID:
C0314657
Organism Attribute
3.

Malnutrition

Food provides the energy and nutrients you need to be healthy. If you don't get enough nutrients -- including proteins, carbohydrates, fats, vitamins, and minerals - you may suffer from malnutrition. Causes of malnutrition include:. -Lack of specific nutrients in your diet. Even the lack of one vitamin can lead to malnutrition. -An unbalanced diet. -Certain medical problems, such as malabsorption syndromes and cancers. Symptoms may include fatigue, dizziness, and weight loss. Or, you may have no symptoms. To diagnose the cause of the problem, your doctor may do blood tests and a nutritional assessment. Treatment may include replacing the missing nutrients and treating the underlying cause.  [from MedlinePlus]

MedGen UID:
56429
Concept ID:
C0162429
Disease or Syndrome
4.

Obesity

Obesity means having too much body fat. It is different from being overweight, which means weighing too much. The weight may come from muscle, bone, fat, and/or body water. Both terms mean that a person's weight is greater than what's considered healthy for his or her height. . Obesity occurs over time when you eat more calories than you use. The balance between calories-in and calories-out differs for each person. Factors that might affect your weight include your genetic makeup, overeating, eating high-fat foods, and not being physically active. . Being obese increases your risk of diabetes, heart disease, stroke, arthritis, and some cancers. If you are obese, losing even 5 to 10 percent of your weight can delay or prevent some of these diseases. For example, that means losing 10 to 20 pounds if you weigh 200 pounds. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
18127
Concept ID:
C0028754
Disease or Syndrome
5.

Aging

Progressive damage to mitochondrial DNA (mtDNA) during life is thought to contribute to aging processes. This notion is supported by the observation of an aging-related accumulation in human mtDNA of oxidative and alkylation derivatives of nucleotides, of small deletions and insertions, and of large deletions, although their low frequency raises questions about their functional significance (Michikawa et al., 1999). [from OMIM]

MedGen UID:
1376
Concept ID:
C0001811
Organism Function
6.

Menarche, age at, quantitative trait locus 3

MedGen UID:
414551
Concept ID:
C2752069
Disease or Syndrome; Finding
7.

Menarche, age at, quantitative trait locus 2

MedGen UID:
414177
Concept ID:
C2752070
Disease or Syndrome; Finding
8.

Body mass index quantitative trait locus 14

MedGen UID:
393916
Concept ID:
C2675914
Disease or Syndrome; Finding
9.

Stature quantitative trait locus 10

MedGen UID:
393671
Concept ID:
C2677152
Disease or Syndrome; Finding
10.

Stature quantitative trait locus 14

MedGen UID:
393665
Concept ID:
C2677124
Disease or Syndrome; Finding
11.

Stature quantitative trait locus 12

MedGen UID:
383034
Concept ID:
C2677133
Disease or Syndrome; Finding
12.

Stature quantitative trait locus 1

Stature (adult height) is an example of a complex genetic trait involving multiple genetic loci. Although complex traits are often difficult to study by linkage analysis, Hirschhorn et al. (2001) suggested that stature is a suitable complex trait for study because of the high heritability and the relatively limited contribution of environmental factors. Thus, linkage analysis has been used to identify quantitative trait loci for stature (STQTL) including STQTL1 on chromosome 6q24, STQTL2 (606256) on chromosome 7q31-q36, STQTL3 (606257) on chromosome 12p11-q14, STQTL4 (606258) on chromosome 13q32-q33, STQTL5 (608982) on chromosome 3p26, STQTL6 (300591) on chromosome Xq24, STQTL7 (609822) on chromosome 1p21, STQTL8 (610114) on chromosome 9q22, STQTL9 (611547) on chromosome 12q14.3, STQTL10 (612221) on chromosome 3q23, STQTL11 (612223) on chromosome 7q21-q22, STQTL12 (612224) on chromosome 4q28-q32, STQTL13 (612226) on chromosome 4p13.3, STQTL14 (612228) on chromosome 20q11.22, STQTL15 (612578) on chromosome 8q21.13, STQTL16 (612579) on chromosome 15q22.31, STQTL17 (612737) on chromosome 7p15, STQTL18 (612892) on chromosome 6p22.1, STQTL19 (612893) on chromosome 6p21.31, STQTL20 (612894) on chromosome 13q14.3, STQTL21 (613440) on chromosome 2q37.1, STQTL22 (613547) on chromosome 16q24, STQTL23 (613548) on chromosome 1p32, and STQTL24 (613549) on chromosome 2p16. See also X-linked short stature (300582) associated with mutations in the SHOX gene (312865). [from OMIM]

MedGen UID:
377910
Concept ID:
C1853477
Disease or Syndrome; Finding
13.

Menarche, age at, quantitative trait locus 1

Age at menarche is a marker of timing of puberty in females. It varies widely between individuals and is a heritable trait (summary by Perry et al., 2014). Genetic Heterogeneity of Age at Menarche Age at menarche has been associated with variation on chromosome 22q13. Other quantitative trait loci (QTLs) associated with age at menarche include MENAQ2 (612882) on chromosome 6q21 and MENAQ3 (612883) on chromosome 9q31. [from OMIM]

MedGen UID:
373423
Concept ID:
C1970484
Disease or Syndrome; Finding
14.

Stature quantitative trait locus 9

MedGen UID:
370591
Concept ID:
C1969061
Disease or Syndrome; Finding
15.

Stature quantitative trait locus 8

MedGen UID:
355269
Concept ID:
C1864691
Disease or Syndrome; Finding
16.

Stature quantitative trait locus 2

MedGen UID:
344057
Concept ID:
C1853476
Disease or Syndrome; Finding
17.

Stature quantitative trait locus 3

MedGen UID:
342888
Concept ID:
C1853475
Disease or Syndrome; Finding
18.

Stature quantitative trait locus 4

MedGen UID:
342887
Concept ID:
C1853474
Disease or Syndrome; Finding
19.

Body mass index quantitative trait locus 2

MedGen UID:
338304
Concept ID:
C1847733
Disease or Syndrome; Finding
20.

Stature quantitative trait locus 6

MedGen UID:
337161
Concept ID:
C1845115
Disease or Syndrome; Finding
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...