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Results: 1 to 20 of 34

1.

Wnt beta-Catenin Signaling Pathway

MedGen UID:
465428
Concept ID:
C3178960
Molecular Function
2.

Tyrosine

Amino acid with side chain -CH2-C6H4OH. [from NCI]

MedGen UID:
21746
Concept ID:
C0041485
Pharmacologic Substance
3.

Phosphorylation

A process in which a phosphate group is added to a molecule, such as a sugar or a protein. [from NCI]

MedGen UID:
10742
Concept ID:
C0031715
Molecular Function
4.

Heterogeneous

Made up of elements or ingredients that are not alike. [from NCI_NCI-GLOSS]

MedGen UID:
5539
Concept ID:
C0019409
5.

ERBB2 expression

MedGen UID:
776921
Concept ID:
CN186049
Finding
6.

Poor prognosis

MedGen UID:
548766
Concept ID:
C0278252
Finding
7.

EGFR-related lung cancer

MedGen UID:
472093
Concept ID:
CN130014
Disease or Syndrome
8.

Disease Response

The pathologic and/or clinical changes that result from treatment. The changes may include eradication of detectable disease, stabilization of disease, or disease progression. [from NCI]

MedGen UID:
309976
Concept ID:
C1704632
Finding
9.

c-erbB2 Gene Amplification

A molecular genetic abnormality indicating the presence of multiple copies of the ERBB2 gene. [from NCI]

MedGen UID:
268775
Concept ID:
C1512127
Cell or Molecular Dysfunction
10.

Thymus Epithelial Neoplasm

MedGen UID:
220416
Concept ID:
C1266101
Neoplastic Process
11.

Trichorhinophalangeal dysplasia type I

Trichorhinophalangeal syndrome type I is a malformation syndrome characterized by distinctive craniofacial and skeletal abnormalities and is inherited as an autosomal dominant (Momeni et al., 2000). TRPS I patients have sparse scalp hair, bulbous tip of the nose, long flat philtrum, thin upper vermilion border, and protruding ears. Skeletal abnormalities include cone-shaped epiphyses at the phalanges, hip malformations, and short stature. [from OMIM]

MedGen UID:
140929
Concept ID:
C0432233
Disease or Syndrome
12.

Corneal fragility keratoglobus, blue sclerae AND joint hypermobility

Brittle cornea syndrome (BCS) is characterized by blue sclerae, corneal rupture after minor trauma, keratoconus or keratoglobus, hyperelasticity of the skin, and hypermobility of the joints (Al-Hussain et al., 2004). Genetic Heterogeneity of Brittle Cornea Syndrome Brittle cornea syndrome-2 (BCS2; 614170) is caused by mutation in the PRDM5 gene (614161) on chromosome 4q25-q26. [from OMIM]

MedGen UID:
78661
Concept ID:
C0268344
Disease or Syndrome
13.

Signal Transduction Pathways

Describes a group of molecules in a cell that work together to control one or more cell functions, such as cell division or cell death. After the first molecule in a pathway receives a signal, it activates another molecule. This process is repeated until the last molecule is activated and the cell function involved is carried out. Abnormal activation of signaling pathways can lead to cancer, and drugs are being developed to block these pathways. This may help block cancer cell growth and kill cancer cells. [from NCI]

MedGen UID:
39530
Concept ID:
C0086982
Molecular Function
14.

Estrogens

A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI) [from NCI]

MedGen UID:
8701
Concept ID:
C0014939
Pharmacologic Substance
15.

Epithelial Neoplasm

neoplasm of epithelial origin, ranging from benign (adenoma and papilloma) to malignant (carcinoma). [from CRISP]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
16.

Neoplasm of breast

Tumors or cancer of the human BREAST. [from MeSH]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
17.

Carcinomatosis

A condition in which cancer is spread widely throughout the body. [from NCI]

MedGen UID:
104704
Concept ID:
C0205699
Neoplastic Process
18.

Cribriform Carcinoma

A carcinoma characterized by the presence of a cribriform architectural pattern. Representative examples include the intraductal cribriform breast carcinoma and invasive cribriform breast carcinoma. [from NCI]

MedGen UID:
104694
Concept ID:
C0205643
Neoplastic Process
19.

Tubular Adenocarcinoma

A malignant glandular neoplasm exhibiting tubular structures. [from NCI]

MedGen UID:
61428
Concept ID:
C0205645
Neoplastic Process
20.

Oxyphilic Adenocarcinoma

A malignant neoplasm composed of large epithelial cells with abundant granular eosinophilic cytoplasm (oncocytes). [from NCI]

MedGen UID:
61427
Concept ID:
C0205642
Neoplastic Process

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