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Hemangioblastoma

MedGen UID:
104929
Concept ID:
C0206734
Neoplastic Process
Synonyms: Haemangioblastoma
SNOMED CT: Hemangioblastoma (81201000); Angioblastoma (81201000)
 
HPO: HP:0010797
Orphanet: ORPHA252054

Definition

A hemangioblastoma is a benign vascular neoplasm that arises almost exclusively in the central nervous system. Hemangioblastomas consist of a tightly packed cluster of small blood vessels forming a mass of up to 1 or 2 cm in diameter. [from HPO]

Recent clinical studies

Etiology

Huntoon K, Wu T, Elder JB, Butman JA, Chew EY, Linehan WM, Oldfield EH, Lonser RR
J Neurosurg 2016 Apr;124(4):971-6. Epub 2015 Oct 30 doi: 10.3171/2015.4.JNS1533. [Epub ahead of print] PMID: 26517769Free PMC Article
Wang Y, Abu-Asab MS, Shen D, Zhuang Z, Chew EY, Chan CC
Graefes Arch Clin Exp Ophthalmol 2014 Aug;252(8):1319-27. Epub 2014 May 24 doi: 10.1007/s00417-014-2660-0. [Epub ahead of print] PMID: 24859386
Seystahl K, Weller M, Bozinov O, Reimann R, Rushing E
Oncol Res Treat 2014;37(4):209-12. Epub 2014 Mar 20 doi: 10.1159/000360780. [Epub ahead of print] PMID: 24732646
Ding D, Starke RM, Evans AJ, Liu KC
J Clin Neurosci 2014 Jun;21(6):1040-3. Epub 2013 Nov 11 doi: 10.1016/j.jocn.2013.08.028. [Epub ahead of print] PMID: 24370504
Tang Z, Wang C, Shi J
J Clin Neurosci 2014 Feb;21(2):333-5. Epub 2013 Sep 4 doi: 10.1016/j.jocn.2013.01.017. [Epub ahead of print] PMID: 24012244

Diagnosis

Wu Y, Wang T, Zhang PP, Yang X, Wang J, Wang CF
J Clin Pathol 2015 Dec;68(12):1020-5. Epub 2015 Jul 22 doi: 10.1136/jclinpath-2015-202900. [Epub ahead of print] PMID: 26201545Free PMC Article
Goo HW, Ra YS
J Neurosurg Pediatr 2015 Jul;16(1):50-3. Epub 2015 Apr 17 doi: 10.3171/2014.12.PEDS14609. [Epub ahead of print] PMID: 25885801
Tomono A, Hara S, Hirose T, Itoh T
Brain Tumor Pathol 2015 Apr;32(2):145-50. Epub 2014 Jun 1 doi: 10.1007/s10014-014-0193-1. [Epub ahead of print] PMID: 24880233
Gluf WM, Dailey AT
J Spinal Cord Med 2014 Nov;37(6):791-4. Epub 2014 Jul 16 doi: 10.1179/2045772314Y.0000000210. [Epub ahead of print] PMID: 25029412Free PMC Article
Montironi R, Lopez-Beltran A, Cheng L, Galosi AB, Montorsi F, Scarpelli M
Eur Urol 2014 Nov;66(5):806-10. Epub 2014 May 2 doi: 10.1016/j.eururo.2014.04.022. [Epub ahead of print] PMID: 24821578

Therapy

Albiñana V, Villar Gómez de Las Heras K, Serrano-Heras G, Segura T, Perona-Moratalla AB, Mota-Pérez M, de Campos JM, Botella LM
Orphanet J Rare Dis 2015 Sep 22;10:118. doi: 10.1186/s13023-015-0343-5. [Epub ahead of print] PMID: 26394686Free PMC Article
Wang Y, Abu-Asab MS, Shen D, Zhuang Z, Chew EY, Chan CC
Graefes Arch Clin Exp Ophthalmol 2014 Aug;252(8):1319-27. Epub 2014 May 24 doi: 10.1007/s00417-014-2660-0. [Epub ahead of print] PMID: 24859386
Seystahl K, Weller M, Bozinov O, Reimann R, Rushing E
Oncol Res Treat 2014;37(4):209-12. Epub 2014 Mar 20 doi: 10.1159/000360780. [Epub ahead of print] PMID: 24732646
Ding D, Starke RM, Evans AJ, Liu KC
J Clin Neurosci 2014 Jun;21(6):1040-3. Epub 2013 Nov 11 doi: 10.1016/j.jocn.2013.08.028. [Epub ahead of print] PMID: 24370504
Yin L, Zhang L, Hao S, Zhang J, Wu Z
J Clin Neurosci 2014 Feb;21(2):250-5. Epub 2013 Nov 8 doi: 10.1016/j.jocn.2013.03.037. [Epub ahead of print] PMID: 24210696

Prognosis

Huntoon K, Wu T, Elder JB, Butman JA, Chew EY, Linehan WM, Oldfield EH, Lonser RR
J Neurosurg 2016 Apr;124(4):971-6. Epub 2015 Oct 30 doi: 10.3171/2015.4.JNS1533. [Epub ahead of print] PMID: 26517769Free PMC Article
Wu Y, Wang T, Zhang PP, Yang X, Wang J, Wang CF
J Clin Pathol 2015 Dec;68(12):1020-5. Epub 2015 Jul 22 doi: 10.1136/jclinpath-2015-202900. [Epub ahead of print] PMID: 26201545Free PMC Article
Schaller T, Bode M, Berlis A, Frühwald MC, Lichtmannegger I, Endhardt K, Märkl B
Pathol Res Pract 2015 Jul;211(7):513-20. Epub 2015 Apr 1 doi: 10.1016/j.prp.2015.03.003. [Epub ahead of print] PMID: 25888144
Rasulic L, Samardzic M, Bascarevic V, Micovic M, Cvrkota I, Zivkovic B
Neurosurg Rev 2015 Jan;38(1):205-9; discussion 209. Epub 2014 Oct 17 doi: 10.1007/s10143-014-0587-x. [Epub ahead of print] PMID: 25323100
Montironi R, Lopez-Beltran A, Cheng L, Galosi AB, Montorsi F, Scarpelli M
Eur Urol 2014 Nov;66(5):806-10. Epub 2014 May 2 doi: 10.1016/j.eururo.2014.04.022. [Epub ahead of print] PMID: 24821578

Clinical prediction guides

Li Z, Feng T, Teng H, Hu Y, Yao Y, Liu Y
Int J Clin Exp Pathol 2015;8(6):7553-8. Epub 2015 Jun 1 PMID: 26261668Free PMC Article
Schaller T, Bode M, Berlis A, Frühwald MC, Lichtmannegger I, Endhardt K, Märkl B
Pathol Res Pract 2015 Jul;211(7):513-20. Epub 2015 Apr 1 doi: 10.1016/j.prp.2015.03.003. [Epub ahead of print] PMID: 25888144
Shi H, Li H, Zhen T, Zhang F, Han A
Int J Clin Exp Pathol 2014;7(10):7054-8. Epub 2014 Sep 15 PMID: 25400795Free PMC Article
Montironi R, Lopez-Beltran A, Cheng L, Galosi AB, Montorsi F, Scarpelli M
Eur Urol 2014 Nov;66(5):806-10. Epub 2014 May 2 doi: 10.1016/j.eururo.2014.04.022. [Epub ahead of print] PMID: 24821578
Doyle LA, Fletcher CD
Am J Surg Pathol 2014 Jan;38(1):119-27. doi: 10.1097/PAS.0b013e3182a266c1. PMID: 24145646

Recent systematic reviews

Slim E, Antoun J, Kourie HR, Schakkal A, Cherfan G
Can J Ophthalmol 2014 Oct;49(5):450-7. doi: 10.1016/j.jcjo.2014.07.007. PMID: 25284102
Sun Hİ, Özduman K, Usseli Mİ, Özgen S, Pamir MN
World Neurosurg 2014 Nov;82(5):836-47. Epub 2014 May 24 doi: 10.1016/j.wneu.2014.05.024. [Epub ahead of print] PMID: 24866229
Binderup ML, Bisgaard ML, Harbud V, Møller HU, Gimsing S, Friis-Hansen L, Hansen Tv, Bagi P, Knigge U, Kosteljanetz M, Bøgeskov L, Thomsen C, Gerdes AM, Ousager LB, Sunde L; Danish vHL Coordination Group
Dan Med J 2013 Dec;60(12):B4763. PMID: 24355456
Tucer B, Ekici MA, Kazanci B, Guclu B
Turk Neurosurg 2013;23(5):672-5. doi: 10.5137/1019-5149.JTN.6172-12.1. PMID: 24101317
Mills SA, Oh MC, Rutkowski MJ, Sughrue ME, Barani IJ, Parsa AT
Neuro Oncol 2012 Aug;14(8):1097-104. Epub 2012 Jun 21 doi: 10.1093/neuonc/nos133. [Epub ahead of print] PMID: 22723428Free PMC Article

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