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Results: 7

1.

platelet-derived growth factor BB

MedGen UID:
67785
Concept ID:
C0246681
Pharmacologic Substance
2.

vessel (polysaccharide)

MedGen UID:
56099
Concept ID:
C0148346
Pharmacologic Substance
3.

Up-Regulation (Physiology)

A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. [from MeSH]

MedGen UID:
12003
Concept ID:
C0041904
Molecular Function
4.

Phosphorylation

A process in which a phosphate group is added to a molecule, such as a sugar or a protein. [from NCI]

MedGen UID:
10742
Concept ID:
C0031715
Molecular Function
5.

Smith McCort dysplasia

Smith-McCort dysplasia is a rare autosomal recessive osteochondrodysplasia characterized by short limbs and trunk with barrel-shaped chest. The radiographic phenotype includes platyspondyly, generalized abnormalities of the epiphyses and metaphyses, and a distinctive lacy appearance of the iliac crest, features identical to those of Dyggve-Melchior-Clausen disease. Spinal cord compression due to atlantoaxial instability occurs in both SMC and DMC (Spranger et al., 1976; Nakamura et al., 1997). Genetic Heterogeneity of Smith-McCort Dysplasia Smith-McCort dysplasia-2 (SMC2; 615222) is caused by mutation in the RAB33B gene (605950) on chromosome 18p. [from OMIM]

MedGen UID:
375887
Concept ID:
C1846431
Disease or Syndrome
6.

Becaplermin

The recombinant analog of endogenous beta (B) chain of the cytokine platelet-derived growth factor (PDGF). Synthesized primarily by megakaryocytes, endogenous PDGF consists of two related peptide chains, PDGF-A and PDGF-B. PDGF functions as a local autocrine and paracrine growth factor in many cellular processes. Recombinant PDGF, alone and in combination with other agents, may be useful in promoting bone formation and soft tissue repair. (NCI04) [from NCI]

MedGen UID:
138472
Concept ID:
C0379135
Pharmacologic Substance
7.

platelet-derived growth factor BB, recombinant

MedGen UID:
99506
Concept ID:
C0140908
Pharmacologic Substance

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