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1.

Lymphoma

Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called Hodgkin disease. The rest are called non-Hodgkin lymphoma. . Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors can't determine why a person gets non-Hodgkin lymphoma. . Non-Hodgkin lymphoma can cause many symptoms, such as : -Swollen, painless lymph nodes in the neck, armpits or groin. -Unexplained weight loss . -Fever . -Soaking night sweats . -Coughing, trouble breathing or chest pain . -Weakness and tiredness that don't go away . -Pain, swelling or a feeling of fullness in the abdomen . Your doctor will perform an exam and lab tests to determine if you have lymphoma. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
44223
Concept ID:
C0024299
Neoplastic Process
2.

Malignant Neoplasm

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body. . Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, biologic therapy, or stem cell transplantation. . NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
14297
Concept ID:
C0006826
Neoplastic Process
3.

Alive

MedGen UID:
749206
Concept ID:
C2584946
Finding
4.

Dead

MedGen UID:
736056
Concept ID:
C1546956
Finding
5.

B-cell lymphoma

A type of lymphoma that originates in B-cells. [from HPO]

MedGen UID:
506689
Concept ID:
CN167917
Finding
6.

Lymphoma

A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells. [from HPO]

MedGen UID:
505322
Concept ID:
CN002422
Finding
7.

Somatotrophinoma, Familial

MedGen UID:
483583
Concept ID:
C3489630
Neoplastic Process
8.

Somatotroph adenoma

AIP-related isolated familial pituitary adenoma (AIP-related FIPA) is defined as the presence of an AIP germline mutation in an individual with a pituitary adenoma (regardless of family history). The most commonly occurring pituitary adenomas in this disorder are growth hormone-secreting adenomas (somatotropinoma), followed by prolactin-secreting adenomas (prolactinoma), growth hormone and prolactin co-secreting adenomas (somatomammotropinoma), and non-functioning pituitary adenomas (NFPA). Rarely TSH- or ACTH-secreting adenomas (thyrotropinoma and corticotropinoma) are observed. Clinical findings result from excess hormone secretion, lack of hormone secretion, and/or mass effects (e.g., headaches, visual field loss). Within the same family, pituitary adenomas can be of the same or different type. Age of onset in AIP-related FIPA is around 20-24 years (age range: 6-66 years). [from GeneReviews]

MedGen UID:
91097
Concept ID:
C0346302
Neoplastic Process
9.

Malignant lymphoma, large B-cell, diffuse

A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that is usually aggressive (fast-growing). It is the most common type of non-Hodgkin lymphoma, and is marked by rapidly growing tumors in the lymph nodes, spleen, liver, bone marrow, or other organs. Other symptoms include fever, night sweats, and weight loss. There are several subtypes of diffuse large B-cell lymphoma. [from NCI]

MedGen UID:
86954
Concept ID:
C0079744
Neoplastic Process
10.

Lymphosarcoma

An antiquated term referring to non-Hodgkin lymphomas composed of small and medium sized lymphocytes. [from NCI]

MedGen UID:
811370
Concept ID:
C3714542
Neoplastic Process
11.

Lymphatism

MedGen UID:
141817
Concept ID:
C0524631
Disease or Syndrome
12.

Lymphadenopathy

A clinical finding indicating that a lymph node is enlarged. Causes include viral and bacterial infections and cancers that affect the lymph nodes. [from NCI]

MedGen UID:
96929
Concept ID:
C0497156
Finding
13.

B-Cell Lymphomas

A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. [from MeSH]

MedGen UID:
86953
Concept ID:
C0079731
Neoplastic Process
14.

Diffuse non-Hodgkin's lymphoma, undifferentiated

MedGen UID:
44226
Concept ID:
C0024306
Neoplastic Process
15.

Mixed Cell Lymphoma

MedGen UID:
44225
Concept ID:
C0024304
Neoplastic Process
16.

Diffuse Mixed Cell Lymphoma

An antiquated term referring to non-Hodgkin lymphomas with a mixed cellular composition. This term applies to both B- and T- cell non-Hodgkin lymphomas. [from NCI]

MedGen UID:
42542
Concept ID:
C0079757
Neoplastic Process
17.

Low Grade Lymphoma

A type of lymphoma that tends to grow and spread slowly, and has few symptoms. Also called indolent lymphoma. [from NCI]

MedGen UID:
42540
Concept ID:
C0079747
Neoplastic Process
18.

Lymphosarcoma

MedGen UID:
42539
Concept ID:
C0079734
Neoplastic Process
19.

Intermediate Grade Lymphoma

A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma and high-grade lymphoma. [from NCI]

MedGen UID:
38239
Concept ID:
C0079741
Neoplastic Process
20.

High Grade Lymphoma

A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma and intermediate-grade lymphoma. [from NCI]

MedGen UID:
38238
Concept ID:
C0079740
Neoplastic Process

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