Display Settings:

Format
Items per page

Send to:

Choose Destination

Results: 1 to 20 of 22

1.

Oxidative Stress

A condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma. [from NCI_NCI-GLOSS]

MedGen UID:
66929
Concept ID:
C0242606
Cell or Molecular Dysfunction
2.

Stress

Everyone feels stressed from time to time. Not all stress is bad. All animals have a stress response, and it can be life-saving. But chronic stress can cause both physical and mental harm. There are at least three different types of stress:: -Routine stress related to the pressures of work, family, and other daily responsibilities. -Stress brought about by a sudden negative change, such as losing a job, divorce, or illness. -Traumatic stress, which happens when you are in danger of being seriously hurt or killed. Examples include a major accident, war, assault, or a natural disaster. This type of stress can cause post-traumatic stress disorder (PTSD). Different people may feel stress in different ways. Some people experience digestive symptoms. Others may have headaches, sleeplessness, depressed mood, anger, and irritability. People under chronic stress get more frequent and severe viral infections, such as the flu or common cold. Vaccines, such as the flu shot, are less effective for them. Some people cope with stress more effectively than others. It's important to know your limits when it comes to stress, so you can avoid more serious health effects. NIH: National Institute of Mental Health.  [from MedlinePlus]

MedGen UID:
20971
Concept ID:
C0038435
Finding
3.

Retinaldehyde

A carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration. [from MeSH]

MedGen UID:
19764
Concept ID:
C0035331
Pharmacologic Substance
4.

Thiazolidinediones

THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). [from MeSH]

MedGen UID:
226242
Concept ID:
C1257987
Pharmacologic Substance
5.

rosiglitazone

The active ingredient in a drug that helps control the amount of glucose (sugar) in the blood and is being studied in the prevention and treatment of some types of cancer. Rosiglitazone stops cells from growing and may prevent the growth of new blood vessels that tumors need to grow. It is a type of thiazolidinedione and a type of antiangiogenesis agent. [from NCI]

MedGen UID:
129650
Concept ID:
C0289313
Pharmacologic Substance
6.

agonists

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
7.

troglitazone

A drug used in diabetes treatment that is being studied for its effect on reducing the risk of cancer cell growth in fat tissue. [from NCI]

MedGen UID:
69969
Concept ID:
C0245514
Pharmacologic Substance
8.

pioglitazone

A drug that is used to treat type 2 diabetes and is being studied in the prevention of head and neck cancer. It may be able to stop leukoplakia (a condition affecting the mouth ) from developing into cancer. It is a type of thiazolidinedione. [from NCI]

MedGen UID:
20220
Concept ID:
C0071097
Pharmacologic Substance
9.

Disease Response

The pathologic and/or clinical changes that result from treatment. The changes may include eradication of detectable disease, stabilization of disease, or disease progression. [from NCI]

MedGen UID:
309976
Concept ID:
C1704632
Finding
10.

Cytoprotective agent

Agents administered before, with, or after cancer therapy to reduce or prevent damage or toxicity to the normal cells. (NCI) [from NCI]

MedGen UID:
224782
Concept ID:
C1268903
Pharmacologic Substance
11.

Drug Interactions

A change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods, or when taken with certain medical conditions. Drug interactions may cause the drug to be more or less effective, or cause effects on the body that are not expected. [from NCI]

MedGen UID:
146913
Concept ID:
C0687133
Molecular Function
12.

Physiological stress

The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions. [from MeSH]

MedGen UID:
105278
Concept ID:
C0449430
Pathologic Function
13.

Endopeptidases

nonEC category which corresponds to EC 3.4.21, EC 3.4.22, EC 3.4.23, EC 3.4.24, and EC 3.4.99. [from CRISP]

MedGen UID:
45389
Concept ID:
C0030946
Pharmacologic Substance
14.

Drug Synergism

The action of a drug in promoting or enhancing the effectiveness of another drug. [from MeSH]

MedGen UID:
41666
Concept ID:
C0013215
Molecular Function
15.

Prelay

MedGen UID:
242819
Concept ID:
C1097080
Pharmacologic Substance
16.

Actos

A drug that is used to treat type 2 diabetes and is being studied in the prevention of head and neck cancer. It may be able to stop leukoplakia (a condition affecting the mouth ) from developing into cancer. It is a type of thiazolidinedione. [from NCI]

MedGen UID:
209066
Concept ID:
C0875954
Pharmacologic Substance
17.

Avandia

MedGen UID:
163734
Concept ID:
C0875967
Pharmacologic Substance
18.

Rezulin

MedGen UID:
147238
Concept ID:
C0701265
Pharmacologic Substance
19.

U 72107A

MedGen UID:
56038
Concept ID:
C0147546
Pharmacologic Substance
20.

Rosiglitazone Cholinate

The cholinate salt form of rosiglitazone, an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. In addition to its ability to lower blood glucose levels, rosiglitazone also exerts anti-inflammatory activity through its ability to inhibit nuclear factor-kappaB (NF-KB) activity and increase I-kappaB levels. In addition, rosiglitazone may cause fluid retention and may worsen congestive heart failure. This agent is also associated with an increased risk of heart attacks. [from NCI]

MedGen UID:
474723
Concept ID:
C3273090
Pharmacologic Substance

Display Settings:

Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...