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Neuroendocrine neoplasm

MedGen UID:
64652
Concept ID:
C0206754
Neoplastic Process
Synonyms: Neuroendocrine Tumor; Neuroendocrine Tumors; Tumor, Neuroendocrine; Tumors, Neuroendocrine
SNOMED CT: Neuroendocrine neoplasm (128928004); Neuroendocrine tumor (255046005)
 

Definition

Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Neuroendocrine neoplasm

Recent clinical studies

Etiology

Sheng R, Xie Y, Zeng M, Ji Y, Rao S, Chen C
Radiol Med 2015 Nov;120(11):1012-20. Epub 2015 Apr 24 doi: 10.1007/s11547-015-0544-y. [Epub ahead of print] PMID: 25907993
Kaemmerer D, Posorski N, von Eggeling F, Ernst G, Hörsch D, Baum RP, Prasad V, Langer R, Esposito I, Klöppel G, Sehner S, Knösel T, Hommann M
Clin Exp Metastasis 2014 Oct;31(7):817-27. Epub 2014 Aug 7 doi: 10.1007/s10585-014-9672-3. [Epub ahead of print] PMID: 25098566
Paik WH, Ryu JK, Song BJ, Kim J, Park JK, Kim YT, Yoon YB
J Korean Med Sci 2013 May;28(5):750-4. Epub 2013 May 2 doi: 10.3346/jkms.2013.28.5.750. PMID: 23678268Free PMC Article
Tatsumoto S, Kodama Y, Sakurai Y, Shinohara T, Katanuma A, Maguchi H
Abdom Imaging 2013 Apr;38(2):358-66. doi: 10.1007/s00261-012-9953-8. PMID: 22945422
Saxena A, Chua TC, Chu F, Al-Zahrani A, Morris DL
Am J Clin Oncol 2012 Oct;35(5):439-45. doi: 10.1097/COC.0b013e31821bc8dd. PMID: 21654315

Diagnosis

Sheng R, Xie Y, Zeng M, Ji Y, Rao S, Chen C
Radiol Med 2015 Nov;120(11):1012-20. Epub 2015 Apr 24 doi: 10.1007/s11547-015-0544-y. [Epub ahead of print] PMID: 25907993
Wang YH, Yang QC, Lin Y, Xue L, Chen MH, Chen J
Medicine (Baltimore) 2014 Dec;93(27):e247. doi: 10.1097/MD.0000000000000247. PMID: 25501094Free PMC Article
Kaemmerer D, Posorski N, von Eggeling F, Ernst G, Hörsch D, Baum RP, Prasad V, Langer R, Esposito I, Klöppel G, Sehner S, Knösel T, Hommann M
Clin Exp Metastasis 2014 Oct;31(7):817-27. Epub 2014 Aug 7 doi: 10.1007/s10585-014-9672-3. [Epub ahead of print] PMID: 25098566
Paik WH, Ryu JK, Song BJ, Kim J, Park JK, Kim YT, Yoon YB
J Korean Med Sci 2013 May;28(5):750-4. Epub 2013 May 2 doi: 10.3346/jkms.2013.28.5.750. PMID: 23678268Free PMC Article
Imperiale A, Addeo P, Averous G, Namer IJ, Bachellier P
J Clin Endocrinol Metab 2013 Jul;98(7):2643-4. Epub 2013 May 13 doi: 10.1210/jc.2013-1942. [Epub ahead of print] PMID: 23671317

Therapy

D'Haese JG, Tosolini C, Ceyhan GO, Kong B, Esposito I, Michalski CW, Kleeff J
World J Gastroenterol 2014 Oct 14;20(38):13893-8. doi: 10.3748/wjg.v20.i38.13893. PMID: 25320524Free PMC Article
Hooper K, Mukhtar F, Li S, Eltoum IA
Cancer Cytopathol 2013 Nov;121(11):653-60. Epub 2013 Jul 9 doi: 10.1002/cncy.21332. [Epub ahead of print] PMID: 23839928
Saxena A, Chua TC, Zhao J, Morris DL
J Surg Oncol 2012 Mar 15;105(4):342-50. Epub 2011 Oct 17 doi: 10.1002/jso.22114. [Epub ahead of print] PMID: 22006355
Forslund T, Kellokumpu I, Elomaa E, Arola J, Nuorva K
Clin Nephrol 2011 Feb;75 Suppl 1:42-6. PMID: 21269593
Mitzner LD, Nohria A, Chacho M, Inzucchi SE
Endocr Pract 2000 Sep-Oct;6(5):370-4. doi: 10.4158/EP.6.5.370. PMID: 11141588

Prognosis

Sheng R, Xie Y, Zeng M, Ji Y, Rao S, Chen C
Radiol Med 2015 Nov;120(11):1012-20. Epub 2015 Apr 24 doi: 10.1007/s11547-015-0544-y. [Epub ahead of print] PMID: 25907993
Wang YH, Yang QC, Lin Y, Xue L, Chen MH, Chen J
Medicine (Baltimore) 2014 Dec;93(27):e247. doi: 10.1097/MD.0000000000000247. PMID: 25501094Free PMC Article
Yang QC, Wang YH, Lin Y, Xue L, Chen YJ, Chen MH, Chen J
Int J Clin Exp Pathol 2014;7(7):4204-12. Epub 2014 Jun 15 PMID: 25120800Free PMC Article
Kaemmerer D, Posorski N, von Eggeling F, Ernst G, Hörsch D, Baum RP, Prasad V, Langer R, Esposito I, Klöppel G, Sehner S, Knösel T, Hommann M
Clin Exp Metastasis 2014 Oct;31(7):817-27. Epub 2014 Aug 7 doi: 10.1007/s10585-014-9672-3. [Epub ahead of print] PMID: 25098566
Paik WH, Ryu JK, Song BJ, Kim J, Park JK, Kim YT, Yoon YB
J Korean Med Sci 2013 May;28(5):750-4. Epub 2013 May 2 doi: 10.3346/jkms.2013.28.5.750. PMID: 23678268Free PMC Article

Clinical prediction guides

Sheng R, Xie Y, Zeng M, Ji Y, Rao S, Chen C
Radiol Med 2015 Nov;120(11):1012-20. Epub 2015 Apr 24 doi: 10.1007/s11547-015-0544-y. [Epub ahead of print] PMID: 25907993
Wang YH, Yang QC, Lin Y, Xue L, Chen MH, Chen J
Medicine (Baltimore) 2014 Dec;93(27):e247. doi: 10.1097/MD.0000000000000247. PMID: 25501094Free PMC Article
Yang QC, Wang YH, Lin Y, Xue L, Chen YJ, Chen MH, Chen J
Int J Clin Exp Pathol 2014;7(7):4204-12. Epub 2014 Jun 15 PMID: 25120800Free PMC Article
Kaemmerer D, Posorski N, von Eggeling F, Ernst G, Hörsch D, Baum RP, Prasad V, Langer R, Esposito I, Klöppel G, Sehner S, Knösel T, Hommann M
Clin Exp Metastasis 2014 Oct;31(7):817-27. Epub 2014 Aug 7 doi: 10.1007/s10585-014-9672-3. [Epub ahead of print] PMID: 25098566
Paik WH, Ryu JK, Song BJ, Kim J, Park JK, Kim YT, Yoon YB
J Korean Med Sci 2013 May;28(5):750-4. Epub 2013 May 2 doi: 10.3346/jkms.2013.28.5.750. PMID: 23678268Free PMC Article

Recent systematic reviews

Fields RC, Busam KJ, Chou JF, Panageas KS, Pulitzer MP, Allen PJ, Kraus DH, Brady MS, Coit DG
Cancer 2012 Jul 1;118(13):3311-20. Epub 2011 Nov 9 doi: 10.1002/cncr.26626. [Epub ahead of print] PMID: 22072529
Saxena A, Chua TC, Chu F, Al-Zahrani A, Morris DL
Am J Clin Oncol 2012 Oct;35(5):439-45. doi: 10.1097/COC.0b013e31821bc8dd. PMID: 21654315

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