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Results: 11

1.

DNA damage

Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand (PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired (DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS. [from MeSH]

MedGen UID:
3880
Concept ID:
C0012860
Cell or Molecular Dysfunction
2.

Mediator brand of benfluorex hydrochloride

An agent that acts as a link between parties, objects, or actions. [from NCI]

MedGen UID:
93010
Concept ID:
C0127400
Pharmacologic Substance
3.

DNA Breaks

Interruptions in the sugar-phosphate backbone of DNA. [from MeSH]

MedGen UID:
354581
Concept ID:
C1721104
Molecular Function
4.

Shock

Shock happens when your blood pressure is too low and not enough blood and oxygen can get to your organs and tissues. Causes of shock include internal or external bleeding, dehydration, burns, or severe vomiting and/or diarrhea. All of these involve the loss of large amounts of body fluids. Shock often accompanies injury. Specific types of shock include: -Hypovolemic shock, caused by internal or external bleeding. -Septic shock, caused by infections in the bloodstream. -Anaphylactic shock, caused by a severe allergic reaction. -Cardiogenic shock, caused by the inability of the heart to pump blood effectively. -Neurogenic shock, caused by damage to the nervous system. Symptoms of shock include cold and sweaty skin, weak but rapid pulse, irregular breathing, dry mouth, dilated pupils and reduced urine flow. Shock is life threatening and it is important to get help right away. Treatment of shock depends on the cause. National Institute of General Medical Sciences.  [from MedlinePlus]

MedGen UID:
20738
Concept ID:
C0036974
Pathologic Function
5.

Phosphorylation

A process in which a phosphate group is added to a molecule, such as a sugar or a protein. [from NCI]

MedGen UID:
10742
Concept ID:
C0031715
Molecular Function
6.

Disease Response

The pathologic and/or clinical changes that result from treatment. The changes may include eradication of detectable disease, stabilization of disease, or disease progression. [from NCI]

MedGen UID:
309976
Concept ID:
C1704632
Finding
7.

Hypertonia

MedGen UID:
115988
Concept ID:
C0235396
Finding
8.

Mass of body structure

In medicine, a lump in the body. It may be caused by the abnormal growth of cells, a cyst, hormonal changes, or an immune reaction. A mass may be benign (not cancer) or malignant (cancer). [from NCI]

MedGen UID:
108287
Concept ID:
C0577559
Finding
9.

Sodium Chloride

A metal halide composed of sodium and chloride with sodium and chloride replacement capabilities. When depleted in the body, sodium must be replaced in order to maintain intracellular osmolarity, nerve conduction, muscle contraction and normal renal function. [from NCI]

MedGen UID:
11483
Concept ID:
C0037494
Pharmacologic Substance
10.

sodium(trans-isoquinolinetetramethylensulfoxidetetrachlororuthenate)

MedGen UID:
194255
Concept ID:
C0676049
Pharmacologic Substance
11.

sodium(trans-indazoletetramethylensulfoxidetetrachlororuthenate)

MedGen UID:
151664
Concept ID:
C0676045
Pharmacologic Substance

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