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Acetylcholine

MedGen UID:
7841
Concept ID:
C0001041
Pharmacologic Substance
Synonyms: 2-(Acetyloxy)-N,N,N-trimethylethanaminium; Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-
SNOMED CT: Acetylcholine preparation (13525006); Acetylcholine (13525006); Acetylcholine (57308006)
 

Definition

A chemical made by some types of nerve cells. It is used to send messages to other cells, including other nerve cells, muscle cells, and gland cells. It is released from the nerve ending and carries signals to cells on the other side of a synapse (space between nerve cells and other cells). Acetylcholine helps control memory and the action of certain muscles. It is a type of neurotransmitter. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGAcetylcholine

Recent clinical studies

Etiology

Profita M, Albano GD, Riccobono L, Di Sano C, Montalbano AM, Gagliardo R, Anzalone G, Bonanno A, Pieper MP, Gjomarkaj M
Immunobiology 2014 May;219(5):392-401. Epub 2014 Jan 25 doi: 10.1016/j.imbio.2014.01.004. [Epub ahead of print] PMID: 24529390
Pienaar PR, Micklesfield LK, Levitt NS, Gooding K, Shore AC, Goedecke JH, Gill JM, Lambert EV
Metab Syndr Relat Disord 2014 Apr;12(3):178-84. Epub 2014 Jan 24 doi: 10.1089/met.2013.0126. [Epub ahead of print] PMID: 24460367
Shin YO, Lee JB
Muscle Nerve 2014 Sep;50(3):407-12. Epub 2014 Jun 16 doi: 10.1002/mus.24173. [Epub ahead of print] PMID: 24408747
Laursen B, Mørk A, Plath N, Kristiansen U, Bastlund JF
Brain Res 2014 Jan 16;1543:253-62. Epub 2013 Nov 11 doi: 10.1016/j.brainres.2013.10.055. [Epub ahead of print] PMID: 24231553
Bäckström G, Lundberg B, Behndig A
Acta Ophthalmol 2013 Mar;91(2):123-6. Epub 2012 Mar 16 doi: 10.1111/j.1755-3768.2011.02376.x. [Epub ahead of print] PMID: 22429618

Diagnosis

Li H, Guo Y, Xiao L, Chen B
Biosens Bioelectron 2014 Sep 15;59:289-92. Epub 2014 Apr 2 doi: 10.1016/j.bios.2014.03.054. [Epub ahead of print] PMID: 24747203
Ong P, Athanasiadis A, Borgulya G, Vokshi I, Bastiaenen R, Kubik S, Hill S, Schäufele T, Mahrholdt H, Kaski JC, Sechtem U
Circulation 2014 Apr 29;129(17):1723-30. Epub 2014 Feb 26 doi: 10.1161/CIRCULATIONAHA.113.004096. [Epub ahead of print] PMID: 24573349
Wei J, Ren J, Liu J, Meng X, Ren X, Chen Z, Tang F
Biosens Bioelectron 2014 Feb 15;52:304-9. Epub 2013 Sep 14 doi: 10.1016/j.bios.2013.09.006. [Epub ahead of print] PMID: 24080209
Weltzin MM, Huang Y, Schulte MK
Eur J Pharmacol 2014 Jun 5;732:159-68. Epub 2012 Jun 23 doi: 10.1016/j.ejphar.2012.06.001. [Epub ahead of print] PMID: 22732654Free PMC Article
Grupe M, Paolone G, Jensen AA, Sandager-Nielsen K, Sarter M, Grunnet M
Biochem Pharmacol 2013 Nov 15;86(10):1487-96. Epub 2013 Sep 16 doi: 10.1016/j.bcp.2013.09.005. [Epub ahead of print] PMID: 24051136Free PMC Article

Therapy

Chernyavsky AI, Galitovskiy V, Shchepotin IB, Jester JV, Grando SA
Invest Ophthalmol Vis Sci 2014 Sep 30;55(10):6921-33. doi: 10.1167/iovs.14-14667. PMID: 25270189
Ong P, Athanasiadis A, Borgulya G, Vokshi I, Bastiaenen R, Kubik S, Hill S, Schäufele T, Mahrholdt H, Kaski JC, Sechtem U
Circulation 2014 Apr 29;129(17):1723-30. Epub 2014 Feb 26 doi: 10.1161/CIRCULATIONAHA.113.004096. [Epub ahead of print] PMID: 24573349
Pienaar PR, Micklesfield LK, Levitt NS, Gooding K, Shore AC, Goedecke JH, Gill JM, Lambert EV
Metab Syndr Relat Disord 2014 Apr;12(3):178-84. Epub 2014 Jan 24 doi: 10.1089/met.2013.0126. [Epub ahead of print] PMID: 24460367
Deflorio C, Catalano M, Fucile S, Limatola C, Grassi F
Muscle Nerve 2014 Jan;49(1):90-7. Epub 2013 Jul 15 doi: 10.1002/mus.23870. [Epub ahead of print] PMID: 23559277
Bäckström G, Lundberg B, Behndig A
Acta Ophthalmol 2013 Mar;91(2):123-6. Epub 2012 Mar 16 doi: 10.1111/j.1755-3768.2011.02376.x. [Epub ahead of print] PMID: 22429618

Prognosis

Yoneyama K, Akashi YJ, Kida K, Ashikaga K, Musha H, Suzuki K, Harada T, Miyake F
Int Heart J 2014;55(2):113-8. Epub 2014 Mar 14 [Epub ahead of print] PMID: 24632951
Sun YX, Gong CH, Liu S, Yuan XP, Yin LJ, Yan L, Shi TT, Dai JH
J Trop Pediatr 2014 Apr;60(2):141-7. Epub 2013 Dec 16 doi: 10.1093/tropej/fmt099. [Epub ahead of print] PMID: 24343824
Park JY, Rha SW, Li YJ, Chen KY, Choi BG, Choi SY, Ryu SK, Choi JW, Kim TK, Kim JM, Bak YS, Lee JH, Im SI, Kim SW, Na JO, Choi CU, Lim HE, Kim JW, Kim EJ, Park CG, Seo HS, Oh DJ
Yonsei Med J 2013 Nov;54(6):1299-304. doi: 10.3349/ymj.2013.54.6.1299. PMID: 24142631Free PMC Article
Sato K, Kaikita K, Nakayama N, Horio E, Yoshimura H, Ono T, Ohba K, Tsujita K, Kojima S, Tayama S, Hokimoto S, Matsui K, Sugiyama S, Yamabe H, Ogawa H
J Am Heart Assoc 2013 Jul 15;2(4):e000227. doi: 10.1161/JAHA.113.000227. PMID: 23858100Free PMC Article
Pochini L, Scalise M, Galluccio M, Pani G, Siminovitch KA, Indiveri C
Biochim Biophys Acta 2012 Mar;1818(3):559-65. Epub 2011 Dec 21 doi: 10.1016/j.bbamem.2011.12.014. [Epub ahead of print] PMID: 22206629

Clinical prediction guides

Sun YX, Gong CH, Liu S, Yuan XP, Yin LJ, Yan L, Shi TT, Dai JH
J Trop Pediatr 2014 Apr;60(2):141-7. Epub 2013 Dec 16 doi: 10.1093/tropej/fmt099. [Epub ahead of print] PMID: 24343824
Weltzin MM, Huang Y, Schulte MK
Eur J Pharmacol 2014 Jun 5;732:159-68. Epub 2012 Jun 23 doi: 10.1016/j.ejphar.2012.06.001. [Epub ahead of print] PMID: 22732654Free PMC Article
Sato K, Kaikita K, Nakayama N, Horio E, Yoshimura H, Ono T, Ohba K, Tsujita K, Kojima S, Tayama S, Hokimoto S, Matsui K, Sugiyama S, Yamabe H, Ogawa H
J Am Heart Assoc 2013 Jul 15;2(4):e000227. doi: 10.1161/JAHA.113.000227. PMID: 23858100Free PMC Article
Kang SH, Chess-Williams R, Anoopkumar-Dukie S, McDermott C
Eur J Pharmacol 2013 Jan 30;700(1-3):102-9. Epub 2012 Dec 5 doi: 10.1016/j.ejphar.2012.11.053. [Epub ahead of print] PMID: 23219793
Esterlis I, Hannestad JO, Bois F, Sewell RA, Tyndale RF, Seibyl JP, Picciotto MR, Laruelle M, Carson RE, Cosgrove KP
J Nucl Med 2013 Jan;54(1):78-82. Epub 2012 Nov 15 doi: 10.2967/jnumed.112.111922. [Epub ahead of print] PMID: 23160789Free PMC Article

Recent systematic reviews

Nocente R, Vitali M, Balducci G, Enea D, Kranzler HR, Ceccanti M
Am J Addict 2013 Sep-Oct;22(5):453-9. Epub 2013 May 15 doi: 10.1111/j.1521-0391.2013.12037.x. [Epub ahead of print] PMID: 23952890
Lewis AS, Picciotto MR
Psychopharmacology (Berl) 2013 Oct;229(3):477-85. Epub 2013 Apr 28 doi: 10.1007/s00213-013-3126-5. [Epub ahead of print] PMID: 23624811Free PMC Article
Nunes EJ, Randall PA, Podurgiel S, Correa M, Salamone JD
Neurosci Biobehav Rev 2013 Nov;37(9 Pt A):2015-25. Epub 2013 Apr 10 doi: 10.1016/j.neubiorev.2013.04.002. [Epub ahead of print] PMID: 23583616
Brunzell DH
Nicotine Tob Res 2012 Nov;14(11):1258-69. Epub 2012 Apr 6 doi: 10.1093/ntr/nts089. [Epub ahead of print] PMID: 22492084Free PMC Article
Zhang J, Summah H, Zhu YG, Qu JM
Respir Res 2011 Dec 17;12:158. doi: 10.1186/1465-9921-12-158. [Epub ahead of print] PMID: 22176972Free PMC Article

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