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Malaria

MedGen UID:
7443
Concept ID:
C0024530
Disease or Syndrome
Synonyms: Fever, Marsh; Fever, Remittent; Infection, Plasmodium; Infections, Plasmodium; Marsh Fever; Paludism; Plasmodium Infection; Plasmodium Infections; Remittent Fever
Modes of inheritance:
not inherited
MedGen UID:
832438
Concept ID:
CN227390
Intellectual Product
Source: Orphanet
Describes a disorder that is not inherited.
not inherited (Orphanet)
SNOMED CT: Malaria (61462000); Paludism (61462000); Plasmodiosis (61462000); Disease due to Plasmodiidae (105649009); Malarial fever (248437004)
 
Orphanet: ORPHA673

Definition

Malaria is a serious disease caused by a parasite. You get it when an infected mosquito bites you. Malaria is a major cause of death worldwide, but it is almost wiped out in the United States. The disease is mostly a problem in developing countries with warm climates. If you travel to these countries, you are at risk. There are four different types of malaria caused by four related parasites. The most deadly type occurs in Africa south of the Sahara Desert. Malaria symptoms include chills, flu-like symptoms, fever, vomiting, diarrhea, and jaundice. A blood test can diagnose it. It can be life-threatening. However, you can treat malaria with drugs. The type of drug depends on which kind of malaria you have and where you were infected. Malaria can be prevented. When traveling to malaria-prone regions. - See your doctor for medicines that protect you . - Wear insect repellent with DEET . - Cover up. - Sleep under mosquito netting . Centers for Disease Control and Prevention.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGMalaria
Follow this link to review classifications for Malaria in Orphanet.

Recent clinical studies

Etiology

Cairns M, Cheung YB, Xu Y, Asante KP, Owusu-Agyei S, Diallo D, Konate AT, Dicko A, Chandramohan D, Greenwood B, Milligan P
Am J Epidemiol 2015 Jun 15;181(12):1008-17. Epub 2015 May 27 doi: 10.1093/aje/kwv010. [Epub ahead of print] PMID: 26022663Free PMC Article
Larsen DA, Bennett A, Silumbe K, Hamainza B, Yukich JO, Keating J, Littrell M, Miller JM, Steketee RW, Eisele TP
Am J Trop Med Hyg 2015 May;92(5):913-21. Epub 2015 Mar 23 doi: 10.4269/ajtmh.14-0347. [Epub ahead of print] PMID: 25802434Free PMC Article
Requena P, Barrios D, Robinson LJ, Samol P, Umbers AJ, Wangnapi R, Ome-Kaius M, Rosanas-Urgell A, Mayor A, López M, de Lazzari E, Arévalo-Herrera M, Fernández-Becerra C, del Portillo H, Chitnis CE, Siba PM, Rogerson S, Mueller I, Bardají A, Menéndez C, Dobaño C
J Immunol 2015 Apr 1;194(7):3275-85. Epub 2015 Feb 27 doi: 10.4049/jimmunol.1401038. [Epub ahead of print] PMID: 25725110
Lynch CA, Bruce J, Bhasin A, Roper C, Cox J, Abeku TA
Trop Med Int Health 2015 Jun;20(6):773-80. Epub 2015 Mar 17 doi: 10.1111/tmi.12480. [Epub ahead of print] PMID: 25689689
Jagannathan P, Nankya F, Stoyanov C, Eccles-James I, Sikyomu E, Naluwu K, Wamala S, Nalubega M, Briggs J, Bowen K, Bigira V, Kapisi J, Kamya MR, Dorsey G, Feeney ME
J Infect Dis 2015 Jun 15;211(12):1987-96. Epub 2014 Dec 17 doi: 10.1093/infdis/jiu814. [Epub ahead of print] PMID: 25520427

Diagnosis

Wangdi K, Gatton ML, Kelly GC, Clements AC
Adv Parasitol 2015 Jun;89:79-107. Epub 2015 May 8 doi: 10.1016/bs.apar.2015.04.002. [Epub ahead of print] PMID: 26003036
Larsen DA, Bennett A, Silumbe K, Hamainza B, Yukich JO, Keating J, Littrell M, Miller JM, Steketee RW, Eisele TP
Am J Trop Med Hyg 2015 May;92(5):913-21. Epub 2015 Mar 23 doi: 10.4269/ajtmh.14-0347. [Epub ahead of print] PMID: 25802434Free PMC Article
Ansah EK, Narh-Bana S, Affran-Bonful H, Bart-Plange C, Cundill B, Gyapong M, Whitty CJ
BMJ 2015 Mar 4;350:h1019. PMID: 25739769Free PMC Article
Lynch CA, Bruce J, Bhasin A, Roper C, Cox J, Abeku TA
Trop Med Int Health 2015 Jun;20(6):773-80. Epub 2015 Mar 17 doi: 10.1111/tmi.12480. [Epub ahead of print] PMID: 25689689
Barber BE, Bird E, Wilkes CS, William T, Grigg MJ, Paramaswaran U, Menon J, Jelip J, Yeo TW, Anstey NM
J Infect Dis 2015 Apr 1;211(7):1104-10. Epub 2014 Oct 9 doi: 10.1093/infdis/jiu562. [Epub ahead of print] PMID: 25301955

Therapy

Cairns M, Cheung YB, Xu Y, Asante KP, Owusu-Agyei S, Diallo D, Konate AT, Dicko A, Chandramohan D, Greenwood B, Milligan P
Am J Epidemiol 2015 Jun 15;181(12):1008-17. Epub 2015 May 27 doi: 10.1093/aje/kwv010. [Epub ahead of print] PMID: 26022663Free PMC Article
Wu Y, Sinden RE, Churcher TS, Tsuboi T, Yusibov V
Adv Parasitol 2015 Jun;89:109-52. Epub 2015 May 8 doi: 10.1016/bs.apar.2015.04.001. [Epub ahead of print] PMID: 26003037
Larsen DA, Bennett A, Silumbe K, Hamainza B, Yukich JO, Keating J, Littrell M, Miller JM, Steketee RW, Eisele TP
Am J Trop Med Hyg 2015 May;92(5):913-21. Epub 2015 Mar 23 doi: 10.4269/ajtmh.14-0347. [Epub ahead of print] PMID: 25802434Free PMC Article
Jagannathan P, Nankya F, Stoyanov C, Eccles-James I, Sikyomu E, Naluwu K, Wamala S, Nalubega M, Briggs J, Bowen K, Bigira V, Kapisi J, Kamya MR, Dorsey G, Feeney ME
J Infect Dis 2015 Jun 15;211(12):1987-96. Epub 2014 Dec 17 doi: 10.1093/infdis/jiu814. [Epub ahead of print] PMID: 25520427
Pinder M, Jawara M, Jarju LB, Salami K, Jeffries D, Adiamoh M, Bojang K, Correa S, Kandeh B, Kaur H, Conway DJ, D'Alessandro U, Lindsay SW
Lancet 2015 Apr 11;385(9976):1436-46. Epub 2014 Dec 9 doi: 10.1016/S0140-6736(14)61007-2. [Epub ahead of print] PMID: 25498847

Prognosis

Cairns M, Cheung YB, Xu Y, Asante KP, Owusu-Agyei S, Diallo D, Konate AT, Dicko A, Chandramohan D, Greenwood B, Milligan P
Am J Epidemiol 2015 Jun 15;181(12):1008-17. Epub 2015 May 27 doi: 10.1093/aje/kwv010. [Epub ahead of print] PMID: 26022663Free PMC Article
Snyman K, Mwangwa F, Bigira V, Kapisi J, Clark TD, Osterbauer B, Greenhouse B, Sturrock H, Gosling R, Liu J, Dorsey G
Am J Trop Med Hyg 2015 Jun;92(6):1207-13. Epub 2015 Apr 13 doi: 10.4269/ajtmh.14-0828. [Epub ahead of print] PMID: 25870429Free PMC Article
Larsen DA, Bennett A, Silumbe K, Hamainza B, Yukich JO, Keating J, Littrell M, Miller JM, Steketee RW, Eisele TP
Am J Trop Med Hyg 2015 May;92(5):913-21. Epub 2015 Mar 23 doi: 10.4269/ajtmh.14-0347. [Epub ahead of print] PMID: 25802434Free PMC Article
Kamya MR, Arinaitwe E, Wanzira H, Katureebe A, Barusya C, Kigozi SP, Kilama M, Tatem AJ, Rosenthal PJ, Drakeley C, Lindsay SW, Staedke SG, Smith DL, Greenhouse B, Dorsey G
Am J Trop Med Hyg 2015 May;92(5):903-12. Epub 2015 Mar 16 doi: 10.4269/ajtmh.14-0312. [Epub ahead of print] PMID: 25778501Free PMC Article
Peak CM, Thuan PD, Britton A, Nguyen TD, Wolbers M, Thanh NV, Buckee CO, Boni MF
Am J Trop Med Hyg 2015 Apr;92(4):811-7. Epub 2015 Feb 9 doi: 10.4269/ajtmh.14-0461. [Epub ahead of print] PMID: 25667053Free PMC Article

Clinical prediction guides

Peak CM, Thuan PD, Britton A, Nguyen TD, Wolbers M, Thanh NV, Buckee CO, Boni MF
Am J Trop Med Hyg 2015 Apr;92(4):811-7. Epub 2015 Feb 9 doi: 10.4269/ajtmh.14-0461. [Epub ahead of print] PMID: 25667053Free PMC Article
Wotodjo AN, Diagne N, Gaudart J, Richard V, Raoult D, Sokhna C
Am J Trop Med Hyg 2015 Mar;92(3):565-8. Epub 2015 Jan 12 doi: 10.4269/ajtmh.14-0485. [Epub ahead of print] PMID: 25582690Free PMC Article
Fernandes RC, Hasan M, Gupta H, Geetha K, Rai PS, Hande MH, D'Souza SC, Adhikari P, Brand A, Satyamoorthy K
Mol Genet Genomics 2015 Jun;290(3):1155-68. Epub 2015 Jan 9 doi: 10.1007/s00438-014-0984-4. [Epub ahead of print] PMID: 25573779
Keating J, Finn TP, Eisele TP, Dery G, Biney E, Kêdoté M, Fayomi B, Yukich JO
Trans R Soc Trop Med Hyg 2014 Oct;108(10):662-9. Epub 2014 Aug 8 doi: 10.1093/trstmh/tru127. [Epub ahead of print] PMID: 25106643
Krzych U, Zarling S, Pichugin A
Immunol Lett 2014 Oct;161(2):189-95. Epub 2014 Apr 5 doi: 10.1016/j.imlet.2014.03.011. [Epub ahead of print] PMID: 24709142

Recent systematic reviews

Saadani Hassani A, Marston BJ
J Acquir Immune Defic Syndr 2015 Apr 15;68 Suppl 3:S306-17. doi: 10.1097/QAI.0000000000000522. PMID: 25768870
Abba K, Kirkham AJ, Olliaro PL, Deeks JJ, Donegan S, Garner P, Takwoingi Y
Cochrane Database Syst Rev 2014 Dec 18;12:CD011431. doi: 10.1002/14651858.CD011431. PMID: 25519857Free PMC Article
Visser BJ, van Vugt M, Grobusch MP
Expert Opin Pharmacother 2014 Oct;15(15):2219-54. Epub 2014 Aug 11 doi: 10.1517/14656566.2014.944499. [Epub ahead of print] PMID: 25110058
Murray CJ, Ortblad KF, Guinovart C, Lim SS, Wolock TM, Roberts DA, Dansereau EA, Graetz N, Barber RM, Brown JC, Wang H, Duber HC, Naghavi M, Dicker D, Dandona L, Salomon JA, Heuton KR, Foreman K, Phillips DE, Fleming TD, Flaxman AD, Phillips BK, Johnson EK, Coggeshall MS, Abd-Allah F, Abera SF, Abraham JP, Abubakar I, Abu-Raddad LJ, Abu-Rmeileh NM, Achoki T, Adeyemo AO, Adou AK, Adsuar JC, Agardh EE, Akena D, Al Kahbouri MJ, Alasfoor D, Albittar MI, Alcalá-Cerra G, Alegretti MA, Alemu ZA, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allen PJ, Alsharif U, Alvarez E, Alvis-Guzman N, Amankwaa AA, Amare AT, Amini H, Ammar W, Anderson BO, Antonio CA, Anwari P, Arnlöv J, Arsenijevic VS, Artaman A, Asghar RJ, Assadi R, Atkins LS, Badawi A, Balakrishnan K, Banerjee A, Basu S, Beardsley J, Bekele T, Bell ML, Bernabe E, Beyene TJ, Bhala N, Bhalla A, Bhutta ZA, Abdulhak AB, Binagwaho A, Blore JD, Basara BB, Bose D, Brainin M, Breitborde N, Castañeda-Orjuela CA, Catalá-López F, Chadha VK, Chang JC, Chiang PP, Chuang TW, Colomar M, Cooper LT, Cooper C, Courville KJ, Cowie BC, Criqui MH, Dandona R, Dayama A, De Leo D, Degenhardt L, Del Pozo-Cruz B, Deribe K, Des Jarlais DC, Dessalegn M, Dharmaratne SD, Dilmen U, Ding EL, Driscoll TR, Durrani AM, Ellenbogen RG, Ermakov SP, Esteghamati A, Faraon EJ, Farzadfar F, Fereshtehnejad SM, Fijabi DO, Forouzanfar MH, Fra Paleo U, Gaffikin L, Gamkrelidze A, Gankpé FG, Geleijnse JM, Gessner BD, Gibney KB, Ginawi IA, Glaser EL, Gona P, Goto A, Gouda HN, Gugnani HC, Gupta R, Gupta R, Hafezi-Nejad N, Hamadeh RR, Hammami M, Hankey GJ, Harb HL, Haro JM, Havmoeller R, Hay SI, Hedayati MT, Pi IB, Hoek HW, Hornberger JC, Hosgood HD, Hotez PJ, Hoy DG, Huang JJ, Iburg KM, Idrisov BT, Innos K, Jacobsen KH, Jeemon P, Jensen PN, Jha V, Jiang G, Jonas JB, Juel K, Kan H, Kankindi I, Karam NE, Karch A, Karema CK, Kaul A, Kawakami N, Kazi DS, Kemp AH, Kengne AP, Keren A, Kereselidze M, Khader YS, Khalifa SE, Khan EA, Khang YH, Khonelidze I, Kinfu Y, Kinge JM, Knibbs L, Kokubo Y, Kosen S, Defo BK, Kulkarni VS, Kulkarni C, Kumar K, Kumar RB, Kumar GA, Kwan GF, Lai T, Balaji AL, Lam H, Lan Q, Lansingh VC, Larson HJ, Larsson A, Lee JT, Leigh J, Leinsalu M, Leung R, Li Y, Li Y, De Lima GM, Lin HH, Lipshultz SE, Liu S, Liu Y, Lloyd BK, Lotufo PA, Machado VM, Maclachlan JH, Magis-Rodriguez C, Majdan M, Mapoma CC, Marcenes W, Marzan MB, Masci JR, Mashal MT, Mason-Jones AJ, Mayosi BM, Mazorodze TT, Mckay AC, Meaney PA, Mehndiratta MM, Mejia-Rodriguez F, Melaku YA, Memish ZA, Mendoza W, Miller TR, Mills EJ, Mohammad KA, Mokdad AH, Mola GL, Monasta L, Montico M, Moore AR, Mori R, Moturi WN, Mukaigawara M, Murthy KS, Naheed A, Naidoo KS, Naldi L, Nangia V, Narayan KM, Nash D, Nejjari C, Nelson RG, Neupane SP, Newton CR, Ng M, Nisar MI, Nolte S, Norheim OF, Nowaseb V, Nyakarahuka L, Oh IH, Ohkubo T, Olusanya BO, Omer SB, Opio JN, Orisakwe OE, Pandian JD, Papachristou C, Caicedo AJ, Patten SB, Paul VK, Pavlin BI, Pearce N, Pereira DM, Pervaiz A, Pesudovs K, Petzold M, Pourmalek F, Qato D, Quezada AD, Quistberg DA, Rafay A, Rahimi K, Rahimi-Movaghar V, Ur Rahman S, Raju M, Rana SM, Razavi H, Reilly RQ, Remuzzi G, Richardus JH, Ronfani L, Roy N, Sabin N, Saeedi MY, Sahraian MA, Samonte GM, Sawhney M, Schneider IJ, Schwebel DC, Seedat S, Sepanlou SG, Servan-Mori EE, Sheikhbahaei S, Shibuya K, Shin HH, Shiue I, Shivakoti R, Sigfusdottir ID, Silberberg DH, Silva AP, Simard EP, Singh JA, Skirbekk V, Sliwa K, Soneji S, Soshnikov SS, Sreeramareddy CT, Stathopoulou VK, Stroumpoulis K, Swaminathan S, Sykes BL, Tabb KM, Talongwa RT, Tenkorang EY, Terkawi AS, Thomson AJ, Thorne-Lyman AL, Towbin JA, Traebert J, Tran BX, Dimbuene ZT, Tsilimbaris M, Uchendu US, Ukwaja KN, Uzun SB, Vallely AJ, Vasankari TJ, Venketasubramanian N, Violante FS, Vlassov VV, Vollset SE, Waller S, Wallin MT, Wang L, Wang X, Wang Y, Weichenthal S, Weiderpass E, Weintraub RG, Westerman R, White RA, Wilkinson JD, Williams TN, Woldeyohannes SM, Wong JQ, Xu G, Yang YC, Yano Y, Yentur GK, Yip P, Yonemoto N, Yoon SJ, Younis M, Yu C, Jin KY, El Sayed Zaki M, Zhao Y, Zheng Y, Zhou M, Zhu J, Zou XN, Lopez AD, Vos T
Lancet 2014 Sep 13;384(9947):1005-70. Epub 2014 Jul 22 doi: 10.1016/S0140-6736(14)60844-8. [Epub ahead of print] PMID: 25059949Free PMC Article
Mbeye NM, ter Kuile FO, Davies MA, Phiri KS, Egger M, Wandeler G; IeDEA-Southern Africa
Trop Med Int Health 2014 Sep;19(9):1057-67. Epub 2014 Jul 8 doi: 10.1111/tmi.12352. [Epub ahead of print] PMID: 25039469Free PMC Article

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