Display Settings:

Format

Send to:

Choose Destination

Antidepressive Agents

MedGen UID:
1588
Concept ID:
C0003289
Pharmacologic Substance
Synonyms: Agents, Antidepressive; Antidepressant Drugs; Antidepressants; Drugs, Antidepressant
SNOMED CT: Antidepressant (372720008); Antidepressant (36236003)
 

Definition

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They work to balance some of the natural chemicals in our brains. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try a few before finding what works best for you. Antidepressants may cause mild side effects that usually do not last long. These may include headache, nausea, sleep problems, restlessness, and sexual problems. Tell your doctor if you have any side effects. You should also let your doctor know if you take any other medicines, vitamins, or herbal supplements. It is important to keep taking your medicines, even if you feel better. Do not stop taking your medicines without talking to your doctor. You often need to stop antidepressants gradually. NIH: National Institute of Mental Health.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews
  • CROGAntidepressive Agents

Recent clinical studies

Etiology

Wong ML, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein S, Arcos-Burgos M, Licinio J
Am J Psychiatry 2014 Dec 1;171(12):1297-309. Epub 2014 Oct 31 doi: 10.1176/appi.ajp.2014.12091165. [Epub ahead of print] PMID: 25220861
Ban L, Gibson JE, West J, Fiaschi L, Sokal R, Smeeth L, Doyle P, Hubbard RB, Tata LJ
BJOG 2014 Nov;121(12):1471-81. Epub 2014 Mar 11 doi: 10.1111/1471-0528.12682. [Epub ahead of print] PMID: 24612301Free PMC Article
Guaiana G, Gupta S, Chiodo D, Davies SJ, Haederle K, Koesters M
Cochrane Database Syst Rev 2013 Dec 17;12:CD008851. doi: 10.1002/14651858.CD008851.pub2. PMID: 24343836
Tsai CJ, Loh el-W, Lin CH, Yu TM, Chan CH, Lan TH
Nephrology (Carlton) 2012 May;17(4):390-7. doi: 10.1111/j.1440-1797.2012.01571.x. PMID: 22260522
Watanabe N, Omori IM, Nakagawa A, Cipriani A, Barbui C, Churchill R, Furukawa TA
Cochrane Database Syst Rev 2011 Dec 7;(12):CD006528. doi: 10.1002/14651858.CD006528.pub2. PMID: 22161405Free PMC Article

Diagnosis

Wong ML, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein S, Arcos-Burgos M, Licinio J
Am J Psychiatry 2014 Dec 1;171(12):1297-309. Epub 2014 Oct 31 doi: 10.1176/appi.ajp.2014.12091165. [Epub ahead of print] PMID: 25220861
Lobo ED, Quinlan T, Prakash A
Clin Pharmacokinet 2014 Aug;53(8):731-40. doi: 10.1007/s40262-014-0149-y. PMID: 24989060
Nagane A, Baba H, Nakano Y, Maeshima H, Hukatsu M, Ozawa K, Suzuki T, Arai H
Psychiatry Res 2014 Aug 15;218(1-2):101-5. Epub 2014 Apr 16 doi: 10.1016/j.psychres.2014.04.013. [Epub ahead of print] PMID: 24768252
Ban L, Gibson JE, West J, Fiaschi L, Sokal R, Smeeth L, Doyle P, Hubbard RB, Tata LJ
BJOG 2014 Nov;121(12):1471-81. Epub 2014 Mar 11 doi: 10.1111/1471-0528.12682. [Epub ahead of print] PMID: 24612301Free PMC Article
Tsai CJ, Loh el-W, Lin CH, Yu TM, Chan CH, Lan TH
Nephrology (Carlton) 2012 May;17(4):390-7. doi: 10.1111/j.1440-1797.2012.01571.x. PMID: 22260522

Therapy

Wong ML, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein S, Arcos-Burgos M, Licinio J
Am J Psychiatry 2014 Dec 1;171(12):1297-309. Epub 2014 Oct 31 doi: 10.1176/appi.ajp.2014.12091165. [Epub ahead of print] PMID: 25220861
Spina E, de Leon J
Expert Opin Drug Metab Toxicol 2014 May;10(5):721-46. Epub 2014 Feb 5 doi: 10.1517/17425255.2014.885504. [Epub ahead of print] PMID: 24494611
Guaiana G, Gupta S, Chiodo D, Davies SJ, Haederle K, Koesters M
Cochrane Database Syst Rev 2013 Dec 17;12:CD008851. doi: 10.1002/14651858.CD008851.pub2. PMID: 24343836
Tsai CJ, Loh el-W, Lin CH, Yu TM, Chan CH, Lan TH
Nephrology (Carlton) 2012 May;17(4):390-7. doi: 10.1111/j.1440-1797.2012.01571.x. PMID: 22260522
Watanabe N, Omori IM, Nakagawa A, Cipriani A, Barbui C, Churchill R, Furukawa TA
Cochrane Database Syst Rev 2011 Dec 7;(12):CD006528. doi: 10.1002/14651858.CD006528.pub2. PMID: 22161405Free PMC Article

Prognosis

Wong ML, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein S, Arcos-Burgos M, Licinio J
Am J Psychiatry 2014 Dec 1;171(12):1297-309. Epub 2014 Oct 31 doi: 10.1176/appi.ajp.2014.12091165. [Epub ahead of print] PMID: 25220861
Lobo ED, Quinlan T, Prakash A
Clin Pharmacokinet 2014 Aug;53(8):731-40. doi: 10.1007/s40262-014-0149-y. PMID: 24989060
Huang CC, Wei IH, Huang CL, Chen KT, Tsai MH, Tsai P, Tun R, Huang KH, Chang YC, Lane HY, Tsai GE
Biol Psychiatry 2013 Nov 15;74(10):734-41. Epub 2013 Apr 3 doi: 10.1016/j.biopsych.2013.02.020. [Epub ahead of print] PMID: 23562005
Bschor T, Uhr M, Baethge C, Lewitzka U, Ising M, Erbe S, Winkelmann P, Ritter D
J Clin Psychopharmacol 2013 Feb;33(1):38-44. doi: 10.1097/JCP.0b013e31827b9495. PMID: 23277245
Tsai CJ, Loh el-W, Lin CH, Yu TM, Chan CH, Lan TH
Nephrology (Carlton) 2012 May;17(4):390-7. doi: 10.1111/j.1440-1797.2012.01571.x. PMID: 22260522

Clinical prediction guides

Wong ML, Dong C, Flores DL, Ehrhart-Bornstein M, Bornstein S, Arcos-Burgos M, Licinio J
Am J Psychiatry 2014 Dec 1;171(12):1297-309. Epub 2014 Oct 31 doi: 10.1176/appi.ajp.2014.12091165. [Epub ahead of print] PMID: 25220861
Huybrechts KF, Palmsten K, Avorn J, Cohen LS, Holmes LB, Franklin JM, Mogun H, Levin R, Kowal M, Setoguchi S, Hernández-Díaz S
N Engl J Med 2014 Jun 19;370(25):2397-407. doi: 10.1056/NEJMoa1312828. PMID: 24941178Free PMC Article
Chua EW, Foulds J, Miller AL, Kennedy MA
Pharmacogenet Genomics 2013 Sep;23(9):494-7. doi: 10.1097/FPC.0b013e328363688d. PMID: 23799451
Huang CC, Wei IH, Huang CL, Chen KT, Tsai MH, Tsai P, Tun R, Huang KH, Chang YC, Lane HY, Tsai GE
Biol Psychiatry 2013 Nov 15;74(10):734-41. Epub 2013 Apr 3 doi: 10.1016/j.biopsych.2013.02.020. [Epub ahead of print] PMID: 23562005
Tsai CJ, Loh el-W, Lin CH, Yu TM, Chan CH, Lan TH
Nephrology (Carlton) 2012 May;17(4):390-7. doi: 10.1111/j.1440-1797.2012.01571.x. PMID: 22260522

Recent systematic reviews

Leong C
Consult Pharm 2014 Apr;29(4):254-63. doi: 10.4140/TCP.n.2014.254. PMID: 24704894
Magni LR, Purgato M, Gastaldon C, Papola D, Furukawa TA, Cipriani A, Barbui C
Cochrane Database Syst Rev 2013 Jul 17;7:CD004185. PMID: 24353997
Guaiana G, Gupta S, Chiodo D, Davies SJ, Haederle K, Koesters M
Cochrane Database Syst Rev 2013 Dec 17;12:CD008851. doi: 10.1002/14651858.CD008851.pub2. PMID: 24343836
Watanabe N, Omori IM, Nakagawa A, Cipriani A, Barbui C, Churchill R, Furukawa TA
Cochrane Database Syst Rev 2011 Dec 7;(12):CD006528. doi: 10.1002/14651858.CD006528.pub2. PMID: 22161405Free PMC Article
Cipriani A, La Ferla T, Furukawa TA, Signoretti A, Nakagawa A, Churchill R, McGuire H, Barbui C
Cochrane Database Syst Rev 2010 Apr 14;(4):CD006117. doi: 10.1002/14651858.CD006117.pub4. PMID: 20393946Free PMC Article

Supplemental Content

Table of contents

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...