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Results: 6

1.

Osteoarthritis susceptibility 1

Osteoarthritis (OA) is a degenerative disease of the joints characterized by degradation of the hyaline articular cartilage and remodeling of the subchondral bone with sclerosis (Meulenbelt et al., 2006). Clinical problems include pain and joint stiffness often leading to significant disability and joint replacement. Osteoarthritis exhibits a clear predilection for specific joints; it appears most commonly in the hip and knee joints and lumbar and cervical spine, as well as in the distal interphalangeal and the first carpometacarpal (base of thumb) and proximal interphalangeal joints of the hand; however, patients with osteoarthritis may have 1, a few, or all of these sites affected (Stefansson et al., 2003). According to a conservative estimate, greater than 70% of the population of the United States at age 65 years is affected by the disease, reflecting its age dependence. [from OMIM]

MedGen UID:
45244
Concept ID:
C0029408
Disease or Syndrome
2.

Cyst

A sac or capsule in the body. It may be filled with fluid or other material. [from NCI]

MedGen UID:
41396
Concept ID:
C0010709
Disease or Syndrome
3.

Bone Cysts

Benign unilocular lytic areas in the proximal end of a long bone with well defined and narrow endosteal margins. The cysts contain fluid and the cyst walls may contain some giant cells. Bone cysts usually occur in males between the ages 3-15 years. [from MeSH]

MedGen UID:
2696
Concept ID:
C0005937
Disease or Syndrome
4.

Bone cyst

A fluid filled cavity that develops with a bone. [from HPO]

MedGen UID:
506659
Concept ID:
CN167788
Finding
5.

Knee osteoarthritis

MedGen UID:
505747
Concept ID:
CN004513
Finding
6.

Osteoarthritis

MedGen UID:
505348
Concept ID:
CN002503
Finding

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