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Results: 1 to 20 of 25

1.

agonists

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
2.

Malignant Breast Neoplasm

Breast cancer affects one in eight women during their lives. Breast cancer kills more women in the United States than any cancer except lung cancer. No one knows why some women get breast cancer, but there are a number of risk factors. Risks that you cannot change include: -Age - the chance of getting breast cancer rises as a woman gets older . -Genes - there are two genes, BRCA1 and BRCA2, that greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested. . -Personal factors - beginning periods before age 12 or going through menopause after age 55. Other risks include being overweight, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35 or having dense breasts. Symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast or discharge from a nipple. Breast self-exam and mammography can help find breast cancer early when it is most treatable. Treatment may consist of radiation, lumpectomy, mastectomy, chemotherapy and hormone therapy. Men can have breast cancer, too, but the number of cases is small. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
651
Concept ID:
C0006142
Neoplastic Process
3.

Breast cancer

MedGen UID:
808165
Concept ID:
CN221572
Disease or Syndrome
4.

Breast carcinoma

The presence of a carcinoma of the breast. [from HPO]

MedGen UID:
428324
Concept ID:
CN002714
Finding
5.

Neoplasm of breast

Tumors or cancer of the human BREAST. [from MeSH]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
6.

Related

MedGen UID:
619805
Concept ID:
C0445223
Finding
7.

Agonist

A drug or substance that binds to a receptor inside a cell or on its surface and causes the same action as the substance that normally binds to the receptor. [from NCI]

MedGen UID:
459858
Concept ID:
C2987634
Pharmacologic Substance
8.

Tamoxifen

MedGen UID:
450034
Concept ID:
CN077559
Pharmacologic Substance
9.

Myeloproliferative syndrome, transient

A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission. [from NCI]

MedGen UID:
331782
Concept ID:
C1834582
Disease or Syndrome
10.

Histone Acetylation

Histone Acetylation involves covalent linkage of acetyl groups to highly basic histone proteins associated with DNA, particularly in active chromatin, and may be involved in regulation of gene expression. [from NCI]

MedGen UID:
257867
Concept ID:
C1156200
Molecular Function
11.

Proliferation

Growth and reproduction of new similar forms, e.g. cells, buds, or offspring. [from NCI]

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
12.

Myopathy with tubular aggregates

Tubular aggregates in muscle, first described by Engel (1964), are structures of variable appearance consisting of an outer tubule containing either one or more microtubule-like structures or amorphous material. They are a nonspecific pathologic finding that may occur in a variety of circumstances, including alcohol- and drug-induced myopathies, exercise-induced cramps or muscle weakness, and inherited myopathies. Tubular aggregates are derived from the sarcoplasmic reticulum (Salviati et al., 1985) and are believed to represent an adaptive mechanism aimed at regulating an increased intracellular level of calcium in order to prevent the muscle fibers from hypercontraction and necrosis (Martin et al., 1997; Muller et al., 2001). Genetic Heterogeneity of Tubular Aggregate Myopathy See also TAM2 (615883), caused by mutation in the ORAI1 gene (610277) on chromosome 12q24. [from OMIM]

MedGen UID:
98050
Concept ID:
C0410207
Disease or Syndrome
13.

Recruitment

MedGen UID:
78772
Concept ID:
C0271510
Disease or Syndrome
14.

Aerodiol

MedGen UID:
365356
Concept ID:
C1951509
Pharmacologic Substance
15.

Soltamox

MedGen UID:
271750
Concept ID:
C1515205
Pharmacologic Substance
16.

Vivelle

MedGen UID:
196344
Concept ID:
C0724374
Pharmacologic Substance
17.

Nolvadex

MedGen UID:
181561
Concept ID:
C0919390
Pharmacologic Substance
18.

ICI-46474

MedGen UID:
152180
Concept ID:
C0700621
Pharmacologic Substance
19.

Ovocyclin

MedGen UID:
148487
Concept ID:
C0699359
Pharmacologic Substance
20.

Estrace

MedGen UID:
148486
Concept ID:
C0699352
Pharmacologic Substance

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