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Mucopolysaccharide

MedGen UID:
9061
Concept ID:
C0017973
Pharmacologic Substance
Synonyms: Glycosaminoglycans; Mucopolysaccharides
SNOMED CT: GAG - Glycosaminoglycan (82565009); Mucopolysaccharide (82565009); Glycosaminoglycan (82565009)
 

Definition

A type of long, unbranched polysaccharide molecule. Glycosaminoglycans are major structural components of cartilage and are also found in the cornea of the eye. [from NCI]

Recent clinical studies

Etiology

Cross EM, Hare DJ
J Inherit Metab Dis 2013 Mar;36(2):189-200. Epub 2013 Feb 6 doi: 10.1007/s10545-012-9572-0. [Epub ahead of print] PMID: 23385295
White KK, Sousa T
J Am Acad Orthop Surg 2013 Jan;21(1):12-22. doi: 10.5435/JAAOS-21-01-12. PMID: 23281467
Kakkis ED
Expert Opin Investig Drugs 2002 May;11(5):675-85. doi: 10.1517/13543784.11.5.675 . PMID: 11996648
Bax MC, Colville GA
Arch Dis Child 1995 Jul;73(1):77-81. PMID: 7639557Free PMC Article
Johnson LA, Lavin PT, Dayal YY, Geller SA, Doos WG, Cooper HS, Gerber JE, Masse ST, Weiland LH, Moertel CG
J Surg Oncol 1986 Dec;33(4):243-5. PMID: 2946897

Diagnosis

White KK, Sousa T
J Am Acad Orthop Surg 2013 Jan;21(1):12-22. doi: 10.5435/JAAOS-21-01-12. PMID: 23281467
Lee YH, Sahu J, O'Brien MS, D'Agati VD, Jimenez SA
J Clin Rheumatol 2011 Sep;17(6):318-22. doi: 10.1097/RHU.0b013e31822be61e. PMID: 21869708
Van Heest AE, House J, Krivit W, Walker K
J Hand Surg Am 1998 Mar;23(2):236-43. doi: 10.1016/S0363-5023(98)80120-2. PMID: 9556262
Lowden JA, Rudd N, Cutz E, Doran TA
Can Med Assoc J 1975 Sep 20;113(6):507-11. PMID: 808260Free PMC Article
Williams HE
Calif Med 1967 Apr;106(4):306-11. PMID: 4227712Free PMC Article

Therapy

Lee YH, Sahu J, O'Brien MS, D'Agati VD, Jimenez SA
J Clin Rheumatol 2011 Sep;17(6):318-22. doi: 10.1097/RHU.0b013e31822be61e. PMID: 21869708
Kumokawa T, Hirata K, Sato K, Kano S
Arzneimittelforschung 2011;61(2):85-91. doi: 10.1055/s-0031-1296172. PMID: 21428242
Zhang W, Lu Y, Xu B, Wu J, Zhang L, Gao M, Zheng S, Wang A, Zhang C, Chen L, Lei N
Cancer Biol Ther 2009 Aug;8(15):1489-99. Epub 2009 Aug 8 [Epub ahead of print] PMID: 19483477
Lu Y, Wang BL
Am J Med Sci 2009 Mar;337(3):195-8. doi: 10.1097/MAJ.0b013e318182ee45. PMID: 19174693
Johnson LA, Lavin PT, Dayal YY, Geller SA, Doos WG, Cooper HS, Gerber JE, Masse ST, Weiland LH, Moertel CG
J Surg Oncol 1986 Dec;33(4):243-5. PMID: 2946897

Prognosis

Bartoloni G, Pucci A, Giorlandino A, Berretta M, Mignosa C, Italia F, Carbone A, Canzonieri V
Cardiovasc Pathol 2013 May-Jun;22(3):e5-10. Epub 2012 Sep 28 doi: 10.1016/j.carpath.2012.08.002. [Epub ahead of print] PMID: 23022500
White KK
Rheumatology (Oxford) 2011 Dec;50 Suppl 5:v26-33. doi: 10.1093/rheumatology/ker393. PMID: 22210667
Lee YH, Sahu J, O'Brien MS, D'Agati VD, Jimenez SA
J Clin Rheumatol 2011 Sep;17(6):318-22. doi: 10.1097/RHU.0b013e31822be61e. PMID: 21869708
Van Heest AE, House J, Krivit W, Walker K
J Hand Surg Am 1998 Mar;23(2):236-43. doi: 10.1016/S0363-5023(98)80120-2. PMID: 9556262
Johnson LA, Lavin PT, Dayal YY, Geller SA, Doos WG, Cooper HS, Gerber JE, Masse ST, Weiland LH, Moertel CG
J Surg Oncol 1986 Dec;33(4):243-5. PMID: 2946897

Clinical prediction guides

Cross EM, Hare DJ
J Inherit Metab Dis 2013 Mar;36(2):189-200. Epub 2013 Feb 6 doi: 10.1007/s10545-012-9572-0. [Epub ahead of print] PMID: 23385295
Langford-Smith KJ, Mercer J, Petty J, Tylee K, Church H, Roberts J, Moss G, Jones S, Wynn R, Wraith JE, Bigger BW
J Inherit Metab Dis 2011 Apr;34(2):499-508. Epub 2010 Dec 18 doi: 10.1007/s10545-010-9254-8. [Epub ahead of print] PMID: 21170681Free PMC Article
Tanzi EL, Perez M
Dermatol Surg 2002 Apr;28(4):305-8. PMID: 11966786
Graf J, Neusel E, Schneider E, Niethard FU
Clin Exp Rheumatol 1993 Jul-Aug;11(4):367-72. PMID: 8403580
Walker V, Smythe PJ, Cook NJ, Ball NA, Veall RM, Whiteman P
J Ment Defic Res 1983 Jun;27 (Pt 2):105-14. PMID: 6225873

Recent systematic reviews

Cross EM, Hare DJ
J Inherit Metab Dis 2013 Mar;36(2):189-200. Epub 2013 Feb 6 doi: 10.1007/s10545-012-9572-0. [Epub ahead of print] PMID: 23385295
Knox DL, Eagle RC Jr, Green WR
Arch Ophthalmol 2007 Mar;125(3):347-53. doi: 10.1001/archopht.125.3.347. PMID: 17353405

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