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Results: 1 to 20 of 62

1.

Vitamins

NOTE: The "vitamin B, other" subclassification (VT109) includes combinations containing only vitamin B complex. Combinations containing only vitamin D are included in subclassification (VT509). Subclassification (VT709) includes combinations of vitamin K only. The "vitamins, other" subclassification (VT809) includes any product in which a vitamin is found in combination with an ingredient which is neither a vitamin nor a mineral. [from NDF-RT]

MedGen UID:
12117
Concept ID:
C0042890
Pharmacologic Substance
2.

Pyridoxal

The 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [from MeSH]

MedGen UID:
48278
Concept ID:
C0034263
Pharmacologic Substance
3.

Vitamin B6

VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine. [from MeSH]

MedGen UID:
39559
Concept ID:
C0087162
Pharmacologic Substance
4.

Seizure

the most dramatic type of seizure [from CHV]

MedGen UID:
20693
Concept ID:
C0036572
Sign or Symptom
5.

pyridoxine

The 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). [from MeSH]

MedGen UID:
19607
Concept ID:
C0034272
Pharmacologic Substance
6.

Pyridoxal Phosphate

This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). [from MeSH]

MedGen UID:
11060
Concept ID:
C0034266
Pharmacologic Substance
7.

Death

Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions. [from MeSH]

MedGen UID:
3696
Concept ID:
C0011065
8.

Neonatal encephalopathy

MedGen UID:
536453
Concept ID:
C0235820
Disease or Syndrome
9.

Seizures

MedGen UID:
472115
Concept ID:
CN130037
Disease or Syndrome
10.

Seizure

MedGen UID:
409523
Concept ID:
C1959629
Finding
11.

Encephalopathy

MedGen UID:
368408
Concept ID:
C1963101
Finding
12.

Pyridoxine-dependent epilepsy

Pyridoxine-dependent epilepsy is characterized by intractable seizures that are not controlled with antiepileptic drugs but that respond both clinically and electrographically to large daily supplements of pyridoxine (vitamin B6). Multiple types of clinical seizures have been reported in individuals with pyridoxine-dependent epilepsy. Dramatic presentations consisting of prolonged seizures and recurrent episodes of status epilepticus are typical; recurrent self-limited events including partial seizures, generalized seizures, atonic seizures, myoclonic events, and infantile spasms also occur. Affected individuals may have electrographic seizures without clinical correlates. Infants with the classic neonatal presentation begin to experience seizures soon after birth. Atypical features include: late-onset seizures (age =3 years); seizures that initially respond to antiepileptic drugs and then become intractable; seizures during early life that do not respond to pyridoxine but that are then controlled with pyridoxine several months later; and prolonged seizure-free intervals (=5 1/2 months) that occur after pyridoxine discontinuation. Intellectual disability is common. [from GeneReviews]

MedGen UID:
340341
Concept ID:
C1849508
Disease or Syndrome
13.

Vitamin B Complex

A group of water-soluble vitamins, some of which are COENZYMES. [from MeSH]

MedGen UID:
53039
Concept ID:
C0042849
Pharmacologic Substance
14.

Leucovorin

The active metabolite of FOLIC ACID. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. [from MeSH]

MedGen UID:
44118
Concept ID:
C0023413
Pharmacologic Substance
15.

Encephalopathy

Degenerative diseases of the brain. [from PSY]

MedGen UID:
39314
Concept ID:
C0085584
Disease or Syndrome
16.

Phosphate

Inorganic salts of phosphoric acid. [from MeSH]

MedGen UID:
18434
Concept ID:
C0031603
Pharmacologic Substance
17.

Anticonvulsants

Medicine to stop, prevent, or control seizures (convulsions). [from NCI]

MedGen UID:
1972
Concept ID:
C0003286
Pharmacologic Substance
18.

Partial seizure

Partial seizure. [from NCI]

MedGen UID:
199670
Concept ID:
C0751495
Sign or Symptom
19.

MedGen UID:
155571
Concept ID:
C0751496
20.

A drug used to lessen the toxic effects of substances that block the action of folic acid, especially the anticancer drug methotrexate. Leucovorin calcium is used to treat some types of anemia and is also used with fluorouracil to treat colorectal cancer. It is also being studied in the treatment of other types of cancer and other conditions. Leucovorin calcium is a form of folic acid. It is a type of chemoprotective agent and a type of chemosensitizing agent. [from NCI]

MedGen UID:
152304
Concept ID:
C0701377

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