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Results: 1 to 20 of 32

1.

Copper

A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. [from MeSH]

MedGen UID:
40479
Concept ID:
C0009968
Pharmacologic Substance
2.

Ubiquitination

The process in which one or more ubiquitin groups are added to a protein. [GOC:ai] [from GO]

MedGen UID:
276919
Concept ID:
C1519751
Molecular Function
3.

bortezomib

A drug that is being studied as a treatment for cancer. It belongs to the family of drugs called dipeptidyl boronic acids. Also called PS-341. [from NCI]

MedGen UID:
222095
Concept ID:
C1176309
Pharmacologic Substance
4.

Cisplatin

An alkylating-like inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. [from NCI]

MedGen UID:
40318
Concept ID:
C0008838
Pharmacologic Substance
5.

Carboplatin

A drug that is used to treat advanced ovarian cancer that has never been treated or symptoms of ovarian cancer that has come back after treatment with other anticancer drugs. It is also used with other drugs to treat advanced, metastatic, or recurrent non-small cell lung cancer and is being studied in the treatment of other types of cancer. Paraplatin is a form of the anticancer drug cisplatin and causes fewer side effects in patients. It attaches to DNA in cells and may kill cancer cells. It is a type of platinum compound. [from NCI]

MedGen UID:
38172
Concept ID:
C0079083
Pharmacologic Substance
6.

oxaliplatin

A drug used with other drugs to treat colorectal cancer that is advanced or has come back. It is also being studied in the treatment of other types of cancer. Eloxatin attaches to DNA in cells and may kill cancer cells. It is a type of platinum compound. [from NCI]

MedGen UID:
19128
Concept ID:
C0069717
Pharmacologic Substance
7.

Malignant Neoplasm

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body. . Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, biologic therapy, or stem cell transplantation. . NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
14297
Concept ID:
C0006826
Neoplastic Process
8.

Sulfur

a kind of isotope [from CHV]

MedGen UID:
11653
Concept ID:
C0038774
Pharmacologic Substance
9.

Down-regulation

A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. [from MeSH]

MedGen UID:
4386
Concept ID:
C0013081
Molecular Function
10.

Related

MedGen UID:
619805
Concept ID:
C0445223
Finding
11.

Ovarian cancer

The ovaries are part of the female reproductive system. They produce a woman's eggs and female hormones. Each ovary is about the size and shape of an almond. Cancer of the ovary is not common, but it causes more deaths than other female reproductive cancers. The sooner ovarian cancer is found and treated, the better your chance for recovery. But ovarian cancer is hard to detect early. Women with ovarian cancer may have no symptoms or just mild symptoms until the disease is in an advanced stage. Then it is hard to treat. Symptoms may include: -A heavy feeling in the pelvis. -Pain in the lower abdomen. - Bleeding from the vagina. - Weight gain or loss. - Abnormal periods. - Unexplained back pain that gets worse. - Gas, nausea, vomiting, or loss of appetite. To diagnose ovarian cancer, doctors do one or more tests. They include a physical exam, a pelvic exam, lab tests, ultrasound, or a biopsy. Treatment is usually surgery followed by chemotherapy. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
216027
Concept ID:
C1140680
Neoplastic Process
12.

Neoplasm of ovary

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008). [from OMIM]

MedGen UID:
181539
Concept ID:
C0919267
Neoplastic Process
13.

cytotoxicity

The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to kill rapidly growing tumor cells. In the killing of tumor cells, other cells that are rapidly growing e.g hair, mucous membranes are also killed. [from NCI]

MedGen UID:
108579
Concept ID:
C0596402
Cell or Molecular Dysfunction
14.

Antioxidants

Antioxidants are substances that may protect your cells against the effects of free radicals. Free radicals are molecules produced when your body breaks down food, or by environmental exposures like tobacco smoke and radiation. Free radicals can damage cells, and may play a role in heart disease, cancer and other diseases. . Antioxidant substances include : - Beta-carotene . - Lutein . - Lycopene. - Selenium. - Vitamin A. - Vitamin C. - Vitamin E. Antioxidants are found in many foods. These include fruits and vegetables, nuts, grains, and some meats, poultry and fish. .  [from MedlinePlus]

MedGen UID:
1608
Concept ID:
C0003402
Pharmacologic Substance
15.

Nealorin

MedGen UID:
308906
Concept ID:
C1516258
Pharmacologic Substance
16.

Neocarbo

MedGen UID:
289846
Concept ID:
C1564517
Pharmacologic Substance
17.

Carbotec

MedGen UID:
275675
Concept ID:
C1516255
Pharmacologic Substance
18.

Carbosin

MedGen UID:
275673
Concept ID:
C1516253
Pharmacologic Substance
19.

Ercar

MedGen UID:
273867
Concept ID:
C1516257
Pharmacologic Substance
20.

Blastocarb

MedGen UID:
273866
Concept ID:
C1516252
Pharmacologic Substance

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